CRCGN014_HEPG2_24H:H02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-phenylenediamine.2hcl 40.8 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1069 genes differentially expressed following the CRCGN014_HEPG2_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BLCAP bladder cancer associated protein 10.0
INPP1 inositol polyphosphate-1-phosphatase 9.78618
ABHD4 abhydrolase domain containing 4 9.66401
CCDC92 coiled-coil domain containing 92 9.41934
DUSP14 dual specificity phosphatase 14 8.76384
KLHL21 kelch-like family member 21 8.56428
TUBB6 tubulin, beta 6 class V 8.2483
LCN2 lipocalin 2 7.68439
DDB2 damage-specific DNA binding protein 2, 48kDa 7.64811
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 7.15379
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 7.08906
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.74697
MICALL1 MICAL-like 1 6.71847
KHDC4 KH domain containing 4, pre-mRNA splicing factor 6.46954
KIFBP kinesin family binding protein 6.14527
MCOLN1 mucolipin 1 6.12905
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 6.09083
PRAF2 PRA1 domain family, member 2 5.97679
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.9731
TIMP2 TIMP metallopeptidase inhibitor 2 5.95365
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.73658
KEAP1 kelch-like ECH-associated protein 1 5.63273
IL4R interleukin 4 receptor 5.61187
STX1A syntaxin 1A (brain) 5.49763
GPC1 glypican 1 5.29142
FOSL1 FOS-like antigen 1 5.19848
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 5.17675
ALAS1 5'-aminolevulinate synthase 1 5.1462
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 5.13517
CASC3 cancer susceptibility candidate 3 5.04216
TESK1 testis-specific kinase 1 4.98537
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.96185
ZW10 zw10 kinetochore protein 4.90548
IGFBP3 insulin-like growth factor binding protein 3 4.87068
TERF2IP telomeric repeat binding factor 2, interacting protein 4.86289
RALGDS ral guanine nucleotide dissociation stimulator 4.74775
CCP110 centriolar coiled coil protein 110kDa 4.73734
PRKCD protein kinase C, delta 4.65245
GADD45A growth arrest and DNA-damage-inducible, alpha 4.64472
NOTCH1 notch 1 4.63066
CNPY3 canopy FGF signaling regulator 3 4.62571
IGHMBP2 immunoglobulin mu binding protein 2 4.52473
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.51202
TBPL1 TBP-like 1 4.46208
PLK3 polo-like kinase 3 4.45657
ANKRD10 ankyrin repeat domain 10 4.42492
CEMIP2 cell migration inducing hyaluronidase 2 4.4004
FBXL12 F-box and leucine-rich repeat protein 12 4.24696
SCAND1 SCAN domain containing 1 4.22072
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.15214
PPIE peptidylprolyl isomerase E (cyclophilin E) 4.10169
RNF25 ring finger protein 25 4.10044
BAX BCL2-associated X protein 4.08911
RGS2 regulator of G-protein signaling 2 4.07655
MAP7D1 MAP7 domain containing 1 4.02262
TXNRD1 thioredoxin reductase 1 4.01916
TOMM34 translocase of outer mitochondrial membrane 34 3.97821
NIT1 nitrilase 1 3.9444
TIGAR TP53 induced glycolysis regulatory phosphatase 3.94405
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 3.84012
KDM3A lysine (K)-specific demethylase 3A 3.80969
CCND3 cyclin D3 3.78234
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.75199
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 3.74947
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 3.74727
FASTKD5 FAST kinase domains 5 3.73212
KDM5A lysine (K)-specific demethylase 5A 3.70237
ATG2A autophagy related 2A 3.69451
MAPK13 mitogen-activated protein kinase 13 3.65059
IER3 immediate early response 3 3.643
DNM1L dynamin 1-like 3.62393
ATG9A autophagy related 9A 3.5949
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.57236
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.52539
LSR lipolysis stimulated lipoprotein receptor 3.49716
RIC8A RIC8 guanine nucleotide exchange factor A 3.48077
PORCN porcupine homolog (Drosophila) 3.45554
RIN1 Ras and Rab interactor 1 3.44997
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.44509
FOXJ3 forkhead box J3 3.43877
PTGES prostaglandin E synthase 3.4262
DUSP6 dual specificity phosphatase 6 3.40877
LAMB3 laminin, beta 3 3.40021
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 3.37185
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.37144
SKIC2 SKI2 subunit of superkiller complex 3.35107
TOR1A torsin family 1, member A (torsin A) 3.34702
GABARAPL1 GABA(A) receptor-associated protein like 1 3.34105
CCDC93 coiled-coil domain containing 93 3.33545
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.31377
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.3067
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 3.29365
FDXR ferredoxin reductase 3.27504
TEX10 testis expressed 10 3.26842
MBD1 methyl-CpG binding domain protein 1 3.25923
ZNF646 zinc finger protein 646 3.23343
TSPYL2 TSPY-like 2 3.22939
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.22521
ULK1 unc-51 like autophagy activating kinase 1 3.22308
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.20929
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 3.20687
SNAI2 snail family zinc finger 2 3.20156
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 3.19045
LRP10 low density lipoprotein receptor-related protein 10 3.16494
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.15773
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 3.14381
ZFP36 ZFP36 ring finger protein 3.13738
SCPEP1 serine carboxypeptidase 1 3.11632
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 3.10878
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.10839
COL17A1 collagen, type XVII, alpha 1 3.07105
FRS2 fibroblast growth factor receptor substrate 2 3.05761
TRIM8 tripartite motif containing 8 3.05026
BAD BCL2-associated agonist of cell death 3.04862
EAPP E2F-associated phosphoprotein 3.04597
SURF2 surfeit 2 3.0407
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 3.03615
CSRNP2 cysteine-serine-rich nuclear protein 2 3.02843
ASB6 ankyrin repeat and SOCS box containing 6 3.01718
PHF1 PHD finger protein 1 2.99594
NISCH nischarin 2.99211
CDPF1 cysteine-rich, DPF motif domain containing 1 2.96899
HBEGF heparin-binding EGF-like growth factor 2.95706
SETD1A SET domain containing 1A 2.94411
XPC xeroderma pigmentosum, complementation group C 2.94139
CCNJL cyclin J-like 2.93719
ZBTB43 zinc finger and BTB domain containing 43 2.93466
BBC3 BCL2 binding component 3 2.93434
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.93414
PRKCQ protein kinase C, theta 2.92257
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.9145
CIC capicua transcriptional repressor 2.91306
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.87729
RALB v-ral simian leukemia viral oncogene homolog B 2.87474
PRKD2 protein kinase D2 2.87412
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.87159
TNIP1 TNFAIP3 interacting protein 1 2.86676
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.85507
SMAD3 SMAD family member 3 2.85116
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.8436
NPDC1 neural proliferation, differentiation and control, 1 2.84187
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.83956
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.81942
UBA1 ubiquitin-like modifier activating enzyme 1 2.81634
CLK3 CDC-like kinase 3 2.81583
CDK9 cyclin-dependent kinase 9 2.81552
CXCL2 chemokine (C-X-C motif) ligand 2 2.81352
AVPI1 arginine vasopressin-induced 1 2.80149
ASCC3 activating signal cointegrator 1 complex subunit 3 2.79439
ZNF79 zinc finger protein 79 2.77961
HDAC7 histone deacetylase 7 2.77712
CPNE7 copine VII 2.76642
FBRS fibrosin 2.75602
MAD2L1BP MAD2L1 binding protein 2.75514
PARP6 poly (ADP-ribose) polymerase family, member 6 2.75389
NOP2 NOP2 nucleolar protein 2.74846
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.73776
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.73388
MICA MHC class I polypeptide-related sequence A 2.73004
TXLNA taxilin alpha 2.72815
CDK5RAP1 CDK5 regulatory subunit associated protein 1 2.72711
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.72386
CLBA1 clathrin binding box of aftiphilin containing 1 2.71931
FASN fatty acid synthase 2.71192
CYBRD1 cytochrome b reductase 1 2.70837
LRRC41 leucine rich repeat containing 41 2.68526
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.67772
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.67481
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.67293
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.65729
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.65023
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.64898
GSDME gasdermin E 2.64337
ATF3 activating transcription factor 3 2.64128
INTS5 integrator complex subunit 5 2.63677
KDM5C lysine (K)-specific demethylase 5C 2.63598
OGFR opioid growth factor receptor 2.6274
TRIM11 tripartite motif containing 11 2.62189
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.62178
MVP major vault protein 2.61744
TMC5 transmembrane channel-like 5 2.61105
DGKA diacylglycerol kinase, alpha 80kDa 2.60883
MED15 mediator complex subunit 15 2.59598
VAT1 vesicle amine transport 1 2.59533
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.59482
GOLT1B golgi transport 1B 2.57737
BECN1 beclin 1, autophagy related 2.57677
RPP38 ribonuclease P/MRP 38kDa subunit 2.57639
PPARG peroxisome proliferator-activated receptor gamma 2.57583
PRPF3 pre-mRNA processing factor 3 2.56795
RGPD1 RANBP2-like and GRIP domain containing 1 2.56605
CCNF cyclin F 2.56482
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.56143
LIF leukemia inhibitory factor 2.55916
RBM22 RNA binding motif protein 22 2.55687
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.54971
STK16 serine/threonine kinase 16 2.54909
ADGRG1 adhesion G protein-coupled receptor G1 2.54566
FOXK2 forkhead box K2 2.54125
MXRA7 matrix-remodelling associated 7 2.54104
GRWD1 glutamate-rich WD repeat containing 1 2.53902
ZNF358 zinc finger protein 358 2.53601
DOHH deoxyhypusine hydroxylase/monooxygenase 2.53298
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.53022
TP53I3 tumor protein p53 inducible protein 3 2.5296
TFE3 transcription factor binding to IGHM enhancer 3 2.52819
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.52099
DOLK dolichol kinase 2.51992
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.51863
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.5176
BRMS1L breast cancer metastasis-suppressor 1-like 2.50317
RTL10 retrotransposon Gag like 10 2.50247
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.50213
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.49235
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.49188
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.48566
ELAC2 elaC ribonuclease Z 2 2.47907
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.4753
ERCC3 excision repair cross-complementation group 3 2.47031
MEA1 male-enhanced antigen 1 2.46961
TJAP1 tight junction associated protein 1 (peripheral) 2.46934
BYSL bystin-like 2.46853
HMGXB3 HMG box domain containing 3 2.46729
UTP11 UTP11 small subunit processome component 2.46536
CRY2 cryptochrome circadian clock 2 2.46136
CDC25B cell division cycle 25B 2.46089
TRAPPC14 trafficking protein particle complex subunit 14 2.45419
KDSR 3-ketodihydrosphingosine reductase 2.43532
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.43196
TBC1D10B TBC1 domain family, member 10B 2.42987
MOCS3 molybdenum cofactor synthesis 3 2.42888
MTCH1 mitochondrial carrier 1 2.42646
USP19 ubiquitin specific peptidase 19 2.42391
BRD2 bromodomain containing 2 2.42343
RETREG2 reticulophagy regulator family member 2 2.42185
PLAUR plasminogen activator, urokinase receptor 2.41928
ZNF282 zinc finger protein 282 2.41808
COL7A1 collagen, type VII, alpha 1 2.41203
FAM53C family with sequence similarity 53, member C 2.4111
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.41045
FUZ fuzzy planar cell polarity protein 2.40991
TMEM115 transmembrane protein 115 2.40739
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.40648
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.40589
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.39735
ZNHIT2 zinc finger, HIT-type containing 2 2.39614
TOE1 target of EGR1, member 1 (nuclear) 2.39421
SIRT1 sirtuin 1 2.38997
VEGFB vascular endothelial growth factor B 2.38857
VPS35L VPS35 endosomal protein sorting factor like 2.38416
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.38078
ZNF557 zinc finger protein 557 2.37914
ZNF212 zinc finger protein 212 2.37589
CYTH1 cytohesin 1 2.36331
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.36315
CDR2L cerebellar degeneration-related protein 2-like 2.36091
NUP58 nucleoporin 58 2.36021
GOLM1 golgi membrane protein 1 2.3597
THUMPD2 THUMP domain containing 2 2.35968
ELMO3 engulfment and cell motility 3 2.35841
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 2.35791
RING1 ring finger protein 1 2.35165
DDR1 discoidin domain receptor tyrosine kinase 1 2.34623
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.34282
RNF19B ring finger protein 19B 2.34261
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 2.33956
MIDEAS mitotic deacetylase associated SANT domain protein 2.33403
ESS2 ess-2 splicing factor homolog 2.33207
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.32955
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.32832
TTC4 tetratricopeptide repeat domain 4 2.32477
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.31997
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 2.3178
MADD MAP-kinase activating death domain 2.30623
TRIM38 tripartite motif containing 38 2.30548
KRT17 keratin 17, type I 2.30478
NKAPD1 NKAP domain containing 1 2.30387
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.30331
TWIST1 twist family bHLH transcription factor 1 2.30165
TUT7 terminal uridylyl transferase 7 2.30115
TTF1 transcription termination factor, RNA polymerase I 2.29752
CSNK1E casein kinase 1, epsilon 2.29705
MICB MHC class I polypeptide-related sequence B 2.29213
TRAFD1 TRAF-type zinc finger domain containing 1 2.29179
ZNF226 zinc finger protein 226 2.29146
TCF15 transcription factor 15 (basic helix-loop-helix) 2.28884
ANGPTL4 angiopoietin-like 4 2.28773
ITPKC inositol-trisphosphate 3-kinase C 2.2877
ARID5A AT rich interactive domain 5A (MRF1-like) 2.28728
RXYLT1 ribitol xylosyltransferase 1 2.28403
OSGIN1 oxidative stress induced growth inhibitor 1 2.27954
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.27533
DEAF1 DEAF1 transcription factor 2.27494
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.27485
AKIP1 A kinase (PRKA) interacting protein 1 2.2659
S100A11 S100 calcium binding protein A11 2.26516
NPTXR neuronal pentraxin receptor 2.26463
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.26238
AEN apoptosis enhancing nuclease 2.26214
JAG2 jagged 2 2.25901
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.25899
STX4 syntaxin 4 2.2585
WDR73 WD repeat domain 73 2.25623
MOK MOK protein kinase 2.25474
LGMN legumain 2.25097
SPATA20 spermatogenesis associated 20 2.25049
TRIM13 tripartite motif containing 13 2.24976
FPGS folylpolyglutamate synthase 2.24803
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.24413
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.24344
KLHL36 kelch-like family member 36 2.24238
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.24162
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.23807
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.23708
CAVIN1 caveolae associated protein 1 2.23124
CYTH2 cytohesin 2 2.23041
KCTD2 potassium channel tetramerization domain containing 2 2.23004
H2BC21 H2B clustered histone 21 2.22979
FAM131A family with sequence similarity 131, member A 2.22963
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.22765
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 2.22598
ITGA6 integrin, alpha 6 2.22479
KIF21B kinesin family member 21B 2.22468
RBM15B RNA binding motif protein 15B 2.20612
FURIN furin (paired basic amino acid cleaving enzyme) 2.20061
NTAN1 N-terminal asparagine amidase 2.20042
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.19825
COL16A1 collagen, type XVI, alpha 1 2.19596
INTS11 integrator complex subunit 11 2.19474
SGSH N-sulfoglucosamine sulfohydrolase 2.18639
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.17889
COPS8 COP9 signalosome subunit 8 2.17863
CDC45 cell division cycle 45 2.17797
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.17719
MED17 mediator complex subunit 17 2.17464
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.17278
PRRC2A proline-rich coiled-coil 2A 2.17197
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 2.17038
FBXW4 F-box and WD repeat domain containing 4 2.17008
USP20 ubiquitin specific peptidase 20 2.16988
HSPB11 heat shock protein family B (small), member 11 2.1668
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.16669
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 2.16602
TSC22D3 TSC22 domain family, member 3 2.1654
BAG3 BCL2-associated athanogene 3 2.16501
RAP1GAP RAP1 GTPase activating protein 2.16204
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 2.16132
LBHD1 LBH domain containing 1 2.16062
IQCC IQ motif containing C 2.15963
RNASE7 ribonuclease, RNase A family, 7 2.15838
GSTM2 glutathione S-transferase mu 2 (muscle) 2.15697
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 2.1569
EXOSC10 exosome component 10 2.1568
THSD1 thrombospondin, type I, domain containing 1 2.15268
CSF3 colony stimulating factor 3 (granulocyte) 2.15122
SAFB2 scaffold attachment factor B2 2.14957
TCEA2 transcription elongation factor A (SII), 2 2.14767
HCFC2 host cell factor C2 2.14619
TICAM1 toll-like receptor adaptor molecule 1 2.14191
XYLT2 xylosyltransferase II 2.14008
PEX26 peroxisomal biogenesis factor 26 2.13678
C6ORF89 chromosome 6 open reading frame 89 2.13596
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.1339
LIPE lipase, hormone-sensitive 2.12683
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.12484
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.12407
TOM1 target of myb1 (chicken) 2.12397
PICK1 protein interacting with PRKCA 1 2.12208
TRIM21 tripartite motif containing 21 2.11519
MINDY1 MINDY lysine 48 deubiquitinase 1 2.10614
IL17RA interleukin 17 receptor A 2.10591
NRBF2 nuclear receptor binding factor 2 2.10587
CCDC90B coiled-coil domain containing 90B 2.10572
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.10276
SF1 splicing factor 1 2.10263
RHOG ras homolog family member G 2.10248
SBNO1 strawberry notch homolog 1 (Drosophila) 2.09908
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 2.09905
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.09457
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.09288
FCMR Fc fragment of IgM receptor 2.0927
ZDHHC4 zinc finger, DHHC-type containing 4 2.0875
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.08552
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.08354
PLXNA1 plexin A1 2.07993
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.07839
CPTP ceramide-1-phosphate transfer protein 2.07635
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 2.07627
ISYNA1 inositol-3-phosphate synthase 1 2.07624
LRRC42 leucine rich repeat containing 42 2.07572
PTK7 protein tyrosine kinase 7 (inactive) 2.07254
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 2.07068
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.06882
ATG101 autophagy related 101 2.06784
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.06439
POMZP3 POM121 and ZP3 fusion 2.0623
CPM carboxypeptidase M 2.0616
MRGBP MRG/MORF4L binding protein 2.06003
ELMO2 engulfment and cell motility 2 2.05844
RCOR3 REST corepressor 3 2.0558
GOLT1A golgi transport 1A 2.05425
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.05078
RBM10 RNA binding motif protein 10 2.05075
GPR87 G protein-coupled receptor 87 2.04923
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 2.04706
PRPF4 pre-mRNA processing factor 4 2.04442
POMP proteasome maturation protein 2.0414
WDR44 WD repeat domain 44 2.03871
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.03799
TEAD3 TEA domain family member 3 2.03401
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.0327
FNBP4 formin binding protein 4 2.03043
LYRM2 LYR motif containing 2 2.0304
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.02989
HRAS Harvey rat sarcoma viral oncogene homolog 2.02693
FHOD1 formin homology 2 domain containing 1 2.02568
BANP BTG3 associated nuclear protein 2.024
SDF2 stromal cell-derived factor 2 2.02349
KPNA6 karyopherin alpha 6 (importin alpha 7) 2.02213
CBX4 chromobox homolog 4 2.02181
SP140L SP140 nuclear body protein-like 2.01742
CCNJ cyclin J 2.01709
BMS1 BMS1 ribosome biogenesis factor 2.0133
PILRB paired immunoglobin-like type 2 receptor beta 2.01022
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.00985
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.00854
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 2.00842
CIB1 calcium and integrin binding 1 (calmyrin) 2.00773
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.00516
NGRN neugrin, neurite outgrowth associated 2.00465
MED24 mediator complex subunit 24 2.00431
IP6K2 inositol hexakisphosphate kinase 2 2.00271

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -9.88324
PCCB propionyl CoA carboxylase, beta polypeptide -9.06183
FGFR4 fibroblast growth factor receptor 4 -8.43762
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -8.19864
NIPSNAP1 nipsnap homolog 1 (C. elegans) -7.6549
PROS1 protein S (alpha) -7.65315
HEATR1 HEAT repeat containing 1 -7.55168
HMGA2 high mobility group AT-hook 2 -7.45392
PEG10 paternally expressed 10 -7.32567
BLMH bleomycin hydrolase -7.19942
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -6.97679
SLC35F2 solute carrier family 35, member F2 -6.94659
RPIA ribose 5-phosphate isomerase A -6.70787
MNAT1 MNAT CDK-activating kinase assembly factor 1 -6.4812
C2CD5 C2 calcium-dependent domain containing 5 -6.42397
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.27637
ANO10 anoctamin 10 -6.24979
PARP1 poly (ADP-ribose) polymerase 1 -6.24637
RSU1 Ras suppressor protein 1 -6.24318
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.92167
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.90944
LBR lamin B receptor -5.89765
TM9SF3 transmembrane 9 superfamily member 3 -5.88481
TCTN1 tectonic family member 1 -5.87006
PLS1 plastin 1 -5.74789
PGM1 phosphoglucomutase 1 -5.70065
ACAA1 acetyl-CoA acyltransferase 1 -5.55439
PYCR1 pyrroline-5-carboxylate reductase 1 -5.5184
DSG2 desmoglein 2 -5.47562
PHKB phosphorylase kinase, beta -5.37149
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -5.36428
CDC20 cell division cycle 20 -5.35791
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.32235
USP6NL USP6 N-terminal like -5.25894
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -5.19842
C5 complement component 5 -5.16376
CCNA2 cyclin A2 -5.15843
ECH1 enoyl CoA hydratase 1, peroxisomal -4.96373
MSRA methionine sulfoxide reductase A -4.90358
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.89505
ZMIZ1 zinc finger, MIZ-type containing 1 -4.8907
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.79865
PSRC1 proline/serine-rich coiled-coil 1 -4.74797
VTN vitronectin -4.56339
CHEK2 checkpoint kinase 2 -4.5273
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -4.52606
APOH apolipoprotein H (beta-2-glycoprotein I) -4.45757
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.43568
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.42711
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -4.39443
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.31149
ANXA7 annexin A7 -4.30901
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -4.30767
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -4.30097
SOAT2 sterol O-acyltransferase 2 -4.29448
PLK1 polo-like kinase 1 -4.24259
APOC3 apolipoprotein C-III -4.21562
ICAM3 intercellular adhesion molecule 3 -4.21298
APOA2 apolipoprotein A-II -4.20311
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.18845
FGA fibrinogen alpha chain -4.15923
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.15681
AMBP alpha-1-microglobulin/bikunin precursor -4.1351
AHSG alpha-2-HS-glycoprotein -4.12859
THAP11 THAP domain containing 11 -4.11784
ADH6 alcohol dehydrogenase 6 (class V) -4.08778
MELK maternal embryonic leucine zipper kinase -4.07905
SLC30A10 solute carrier family 30, member 10 -4.07042
MYC v-myc avian myelocytomatosis viral oncogene homolog -4.06315
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -4.05417
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -4.04155
FGB fibrinogen beta chain -3.97055
DPYS dihydropyrimidinase -3.96298
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.95752
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.93521
CDK4 cyclin-dependent kinase 4 -3.92175
PAH phenylalanine hydroxylase -3.90636
ADI1 acireductone dioxygenase 1 -3.88964
ENOPH1 enolase-phosphatase 1 -3.88953
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -3.87973
A1CF APOBEC1 complementation factor -3.87694
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.87031
PLG plasminogen -3.84035
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.83849
SPAG4 sperm associated antigen 4 -3.83081
HYOU1 hypoxia up-regulated 1 -3.82528
ANG angiogenin, ribonuclease, RNase A family, 5 -3.81637
NR1H4 nuclear receptor subfamily 1, group H, member 4 -3.80817
LIPC lipase, hepatic -3.79153
MRPL12 mitochondrial ribosomal protein L12 -3.78138
COMMD10 COMM domain containing 10 -3.76943
CPB2 carboxypeptidase B2 (plasma) -3.76903
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -3.76744
RPS5 ribosomal protein S5 -3.76403
CLIC4 chloride intracellular channel 4 -3.76152
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -3.72271
MYO10 myosin X -3.69677
HADH hydroxyacyl-CoA dehydrogenase -3.69151
FBF1 Fas (TNFRSF6) binding factor 1 -3.6897
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.64439
MBL2 mannose-binding lectin (protein C) 2, soluble -3.59907
ITGB5 integrin, beta 5 -3.58473
ASGR1 asialoglycoprotein receptor 1 -3.57721
ZNF586 zinc finger protein 586 -3.56676
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.5513
FGG fibrinogen gamma chain -3.5461
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -3.54547
KIF4A kinesin family member 4A -3.54257
ADTRP androgen-dependent TFPI-regulating protein -3.51847
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -3.50939
SKIC8 SKI8 subunit of superkiller complex -3.48922
ASGR2 asialoglycoprotein receptor 2 -3.46865
PECR peroxisomal trans-2-enoyl-CoA reductase -3.46535
CDK1 cyclin-dependent kinase 1 -3.46199
APOA1 apolipoprotein A-I -3.46141
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.452
TLR4 toll-like receptor 4 -3.44646
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.43461
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -3.43425
SAA4 serum amyloid A4, constitutive -3.43164
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.42485
ERBB3 erb-b2 receptor tyrosine kinase 3 -3.41362
KANK1 KN motif and ankyrin repeat domains 1 -3.4125
NNT nicotinamide nucleotide transhydrogenase -3.41098
BZW2 basic leucine zipper and W2 domains 2 -3.3924
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -3.38953
TM4SF5 transmembrane 4 L six family member 5 -3.37955
AKR1D1 aldo-keto reductase family 1, member D1 -3.36514
RGN regucalcin -3.36169
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -3.35824
HPD 4-hydroxyphenylpyruvate dioxygenase -3.35698
GPHN gephyrin -3.35497
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -3.35279
APOM apolipoprotein M -3.34648
ORM2 orosomucoid 2 -3.33583
SERP1 stress-associated endoplasmic reticulum protein 1 -3.33384
ACLY ATP citrate lyase -3.33013
LDHD lactate dehydrogenase D -3.32096
FABP1 fatty acid binding protein 1, liver -3.30531
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -3.30044
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -3.29401
F9 coagulation factor IX -3.27989
MRPS30 mitochondrial ribosomal protein S30 -3.27273
GMDS GDP-mannose 4,6-dehydratase -3.27213
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -3.26055
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -3.23806
DENND2D DENN/MADD domain containing 2D -3.21793
OXCT1 3-oxoacid CoA transferase 1 -3.21607
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.21024
RNASE4 ribonuclease, RNase A family, 4 -3.19794
CTNND2 catenin (cadherin-associated protein), delta 2 -3.19495
CDKN2A cyclin-dependent kinase inhibitor 2A -3.18713
KIF15 kinesin family member 15 -3.18209
SCARB1 scavenger receptor class B, member 1 -3.17683
GPD1L glycerol-3-phosphate dehydrogenase 1-like -3.16906
BFSP2 beaded filament structural protein 2, phakinin -3.168
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.16536
AMDHD2 amidohydrolase domain containing 2 -3.15695
SYNE2 spectrin repeat containing, nuclear envelope 2 -3.15685
CPNE2 copine II -3.15458
CFHR2 complement factor H-related 2 -3.14642
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -3.12878
KLHDC2 kelch domain containing 2 -3.12089
GC group-specific component (vitamin D binding protein) -3.11997
TOP2A topoisomerase (DNA) II alpha 170kDa -3.11899
PTGES3 prostaglandin E synthase 3 (cytosolic) -3.11238
AK4 adenylate kinase 4 -3.10554
RPL36AL ribosomal protein L36a-like -3.1007
RHOBTB1 Rho-related BTB domain containing 1 -3.09291
CRIPTO3 cripto, EGF-CFC family member 3 -3.09189
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -3.08538
AMT aminomethyltransferase -3.07918
ZNF835 zinc finger protein 835 -3.06796
CER1 cerberus 1, DAN family BMP antagonist -3.04832
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.04325
SNTG1 syntrophin, gamma 1 -3.02622
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -3.02431
GIPC2 GIPC PDZ domain containing family, member 2 -3.02355
FGL1 fibrinogen-like 1 -3.01985
APOB apolipoprotein B -3.00542
TFB1M transcription factor B1, mitochondrial -2.99315
TPM1 tropomyosin 1 (alpha) -2.96976
STX7 syntaxin 7 -2.96795
CANX calnexin -2.96645
PXMP2 peroxisomal membrane protein 2, 22kDa -2.94931
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.94822
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.93119
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.93118
DCK deoxycytidine kinase -2.9292
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.92886
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.92807
ATRNL1 attractin-like 1 -2.92511
ADGRG6 adhesion G protein-coupled receptor G6 -2.92249
MTTP microsomal triglyceride transfer protein -2.91237
ADAM10 ADAM metallopeptidase domain 10 -2.91013
AURKB aurora kinase B -2.9091
COBL cordon-bleu WH2 repeat protein -2.89399
TOMM70 translocase of outer mitochondrial membrane 70 -2.89162
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.88554
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.88286
TOP2B topoisomerase (DNA) II beta 180kDa -2.87971
HPX hemopexin -2.87296
ETFA electron-transfer-flavoprotein, alpha polypeptide -2.87191
SLC17A2 solute carrier family 17, member 2 -2.87146
MAT1A methionine adenosyltransferase I, alpha -2.8707
PIPOX pipecolic acid oxidase -2.86791
NRIP1 nuclear receptor interacting protein 1 -2.86486
FBL fibrillarin -2.83531
AGMAT agmatine ureohydrolase (agmatinase) -2.83496
CFHR5 complement factor H-related 5 -2.82687
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.82615
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.82494
DCTPP1 dCTP pyrophosphatase 1 -2.81596
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.81397
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.80623
ACSM2A acyl-CoA synthetase medium-chain family member 2A -2.79429
USO1 USO1 vesicle transport factor -2.78962
PCNA proliferating cell nuclear antigen -2.78294
AGXT alanine-glyoxylate aminotransferase -2.77873
DMAC2L distal membrane arm assembly component 2 like -2.77542
RAB4A RAB4A, member RAS oncogene family -2.77102
TTF2 transcription termination factor, RNA polymerase II -2.76761
INHBE inhibin, beta E -2.76507
CDK14 cyclin-dependent kinase 14 -2.76022
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.75432
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.74389
ARB2A ARB2 cotranscriptional regulator A -2.74389
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.74342
ZNF253 zinc finger protein 253 -2.73237
TMEM97 transmembrane protein 97 -2.72874
SELENOT selenoprotein T -2.7261
RFC2 replication factor C (activator 1) 2, 40kDa -2.72512
BIRC5 baculoviral IAP repeat containing 5 -2.72222
NUP93 nucleoporin 93kDa -2.72213
BMP4 bone morphogenetic protein 4 -2.71957
MYL9 myosin, light chain 9, regulatory -2.71956
RUNDC3B RUN domain containing 3B -2.7185
E2F5 E2F transcription factor 5, p130-binding -2.71541
HAVCR1 hepatitis A virus cellular receptor 1 -2.71481
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.70723
NLGN4Y neuroligin 4, Y-linked -2.68955
TPD52-MRPS28 TPD52-MRPS28 readthrough -2.68631
PMP2 peripheral myelin protein 2 -2.68571
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -2.68083
FMO1 flavin containing monooxygenase 1 -2.67088
GET1 guided entry of tail-anchored proteins factor 1 -2.67064
C8A complement component 8, alpha polypeptide -2.66858
HPR haptoglobin-related protein -2.6657
TM9SF2 transmembrane 9 superfamily member 2 -2.66531
VRK2 vaccinia related kinase 2 -2.65994
ARL2 ADP-ribosylation factor-like 2 -2.65984
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -2.65708
S100A4 S100 calcium binding protein A4 -2.65596
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.65594
C8B complement component 8, beta polypeptide -2.65337
GLDC glycine dehydrogenase (decarboxylating) -2.65061
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.64993
CNTLN centlein, centrosomal protein -2.64728
OSBPL10 oxysterol binding protein-like 10 -2.64554
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.63899
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.63801
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.63633
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.63532
MRPL19 mitochondrial ribosomal protein L19 -2.63519
USP46 ubiquitin specific peptidase 46 -2.62393
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.61992
GRIA3 glutamate receptor, ionotropic, AMPA 3 -2.61865
MYLK3 myosin light chain kinase 3 -2.6148
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -2.60873
PRODH2 proline dehydrogenase (oxidase) 2 -2.60693
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -2.59701
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.59416
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.59259
SNX11 sorting nexin 11 -2.59147
BNC2 basonuclin 2 -2.5911
BMP6 bone morphogenetic protein 6 -2.58972
AMOT angiomotin -2.58726
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.58713
NUBPL nucleotide binding protein-like -2.57845
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.57039
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.56639
GDF7 growth differentiation factor 7 -2.5652
EIF5 eukaryotic translation initiation factor 5 -2.55752
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.55648
ELOVL6 ELOVL fatty acid elongase 6 -2.55331
NTAQ1 N-terminal glutamine amidase 1 -2.55277
FABP7 fatty acid binding protein 7, brain -2.54644
NUP133 nucleoporin 133kDa -2.53958
GLYAT glycine-N-acyltransferase -2.53698
GLRX5 glutaredoxin 5 -2.5323
HBG1 hemoglobin, gamma A -2.53182
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.53147
DOCK2 dedicator of cytokinesis 2 -2.52511
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.52422
APOC1 apolipoprotein C-I -2.5214
GPC3 glypican 3 -2.51672
FAM114A1 family with sequence similarity 114, member A1 -2.51642
ANKRD46 ankyrin repeat domain 46 -2.51452
RELN reelin -2.51321
NHP2 NHP2 ribonucleoprotein -2.51193
MASP2 mannan-binding lectin serine peptidase 2 -2.51032
TMX1 thioredoxin-related transmembrane protein 1 -2.50881
TRIM24 tripartite motif containing 24 -2.50698
PCDHGA3 protocadherin gamma subfamily A, 3 -2.49378
NCAPD2 non-SMC condensin I complex, subunit D2 -2.49091
ITGB7 integrin, beta 7 -2.48637
EVL Enah/Vasp-like -2.48635
STAP2 signal transducing adaptor family member 2 -2.48556
KIF5A kinesin family member 5A -2.48474
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.48456
GPR6 G protein-coupled receptor 6 -2.4804
TBC1D5 TBC1 domain family, member 5 -2.47697
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.47156
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.47034
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -2.4686
CD5L CD5 molecule-like -2.46608
CDH19 cadherin 19, type 2 -2.46089
STIMATE STIM activating enhancer -2.45463
FKBP3 FK506 binding protein 3, 25kDa -2.45109
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.44998
ELP4 elongator acetyltransferase complex subunit 4 -2.44303
KNG1 kininogen 1 -2.4405
PNN pinin, desmosome associated protein -2.44022
FGL2 fibrinogen-like 2 -2.43421
FHL5 four and a half LIM domains 5 -2.43087
LEPROT leptin receptor overlapping transcript -2.427
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.41974
FIG4 FIG4 phosphoinositide 5-phosphatase -2.41957
CCR2 chemokine (C-C motif) receptor 2 -2.41597
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.41405
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.41195
TRIP13 thyroid hormone receptor interactor 13 -2.4065
SEC23A Sec23 homolog A (S. cerevisiae) -2.40421
NOTCH2 notch 2 -2.40332
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.40165
CXCL6 chemokine (C-X-C motif) ligand 6 -2.40102
CLASP2 cytoplasmic linker associated protein 2 -2.40097
IL17RB interleukin 17 receptor B -2.40095
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -2.40066
OR5I1 olfactory receptor, family 5, subfamily I, member 1 -2.4003
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -2.39542
COPZ1 coatomer protein complex, subunit zeta 1 -2.39512
VCAM1 vascular cell adhesion molecule 1 -2.39341
LAG3 lymphocyte-activation gene 3 -2.39275
ENDOU endonuclease, polyU-specific -2.39172
AGPS alkylglycerone phosphate synthase -2.39158
PKLR pyruvate kinase, liver and RBC -2.38896
DCPH1 damage control phosphatase 1 -2.38883
CRTAP cartilage associated protein -2.38844
ACOX2 acyl-CoA oxidase 2, branched chain -2.38558
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.38353
CFHR3 complement factor H-related 3 -2.38332
NCOA3 nuclear receptor coactivator 3 -2.38225
FAM110A family with sequence similarity 110, member A -2.381
C8G complement component 8, gamma polypeptide -2.37924
QSER1 glutamine and serine rich 1 -2.37794
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.37774
GLOD4 glyoxalase domain containing 4 -2.37765
PGK1 phosphoglycerate kinase 1 -2.37664
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.37298
PLA2G3 phospholipase A2, group III -2.37228
CLCC1 chloride channel CLIC-like 1 -2.36708
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -2.36686
ZFP91 ZFP91 zinc finger protein -2.36364
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.36168
ANO3 anoctamin 3 -2.35898
NPC1L1 NPC1-like 1 -2.35836
ARMC8 armadillo repeat containing 8 -2.35685
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -2.35641
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -2.35618
PLSCR4 phospholipid scramblase 4 -2.35504
IQGAP2 IQ motif containing GTPase activating protein 2 -2.35158
RBMX RNA binding motif protein, X-linked -2.34759
TTC27 tetratricopeptide repeat domain 27 -2.34628
U2SURP U2 snRNP-associated SURP domain containing -2.34611
THOC7 THO complex 7 -2.34582
FHIT fragile histidine triad -2.34525
TSPAN4 tetraspanin 4 -2.34401
TRIB3 tribbles pseudokinase 3 -2.34181
CPED1 cadherin-like and PC-esterase domain containing 1 -2.34133
PEBP1 phosphatidylethanolamine binding protein 1 -2.34075
RERGL RERG/RAS-like -2.33831
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.33786
STMN1 stathmin 1 -2.33688
FBXO5 F-box protein 5 -2.33497
PUM2 pumilio RNA-binding family member 2 -2.33448
TSPO2 translocator protein 2 -2.33009
SYN3 synapsin III -2.32982
LARS1 leucyl-tRNA synthetase 1 -2.32751
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -2.32235
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.32061
MTNR1A melatonin receptor 1A -2.31494
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -2.31039
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -2.30957
MSH2 mutS homolog 2 -2.30677
IGFBP1 insulin-like growth factor binding protein 1 -2.30644
EEA1 early endosome antigen 1 -2.30258
GDI2 GDP dissociation inhibitor 2 -2.30186
OTC ornithine carbamoyltransferase -2.29865
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -2.29581
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -2.29388
OIP5 Opa interacting protein 5 -2.29349
MRPS27 mitochondrial ribosomal protein S27 -2.28676
RGS7 regulator of G-protein signaling 7 -2.28333
DCN decorin -2.28282
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.28212
SYNPO2L synaptopodin 2-like -2.28209
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -2.27935
SNCAIP synuclein, alpha interacting protein -2.27772
MYRIP myosin VIIA and Rab interacting protein -2.27656
SV2C synaptic vesicle glycoprotein 2C -2.27421
GNAS GNAS complex locus -2.27331
ZNF287 zinc finger protein 287 -2.27201
UBE2C ubiquitin-conjugating enzyme E2C -2.27031
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.27028
ZNF175 zinc finger protein 175 -2.26918
RHOT1 ras homolog family member T1 -2.26785
TF transferrin -2.2674
CD163 CD163 molecule -2.25734
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.25499
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough -2.25225
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.25188
ZNF528 zinc finger protein 528 -2.25
MYL4 myosin, light chain 4, alkali; atrial, embryonic -2.24981
CDK6 cyclin-dependent kinase 6 -2.24925
SLC38A4 solute carrier family 38, member 4 -2.24902
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -2.24612
ABI3BP ABI family, member 3 (NESH) binding protein -2.24598
ZIM2 zinc finger, imprinted 2 -2.24562
TTR transthyretin -2.24252
SCN1A sodium channel, voltage gated, type I alpha subunit -2.242
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -2.24185
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.24181
ANGPTL8 angiopoietin like 8 -2.24153
TRMT9B tRNA methyltransferase 9B (putative) -2.23544
EML4 echinoderm microtubule associated protein like 4 -2.23321
VASH2 vasohibin 2 -2.23261
GLB1 galactosidase, beta 1 -2.22914
VSIG4 V-set and immunoglobulin domain containing 4 -2.22726
CTPS2 CTP synthase 2 -2.22511
L2HGDH L-2-hydroxyglutarate dehydrogenase -2.22442
LRRC8D leucine rich repeat containing 8 family, member D -2.22434
KRT36 keratin 36, type I -2.22294
DHPS deoxyhypusine synthase -2.22173
ECHDC2 enoyl CoA hydratase domain containing 2 -2.22027
CUX1 cut-like homeobox 1 -2.21872
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -2.21771
PEG3 paternally expressed 3 -2.21757
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 -2.21514
AFM afamin -2.2126
NENF neudesin neurotrophic factor -2.2123
IL36RN interleukin 36 receptor antagonist -2.21092
TTC9 tetratricopeptide repeat domain 9 -2.20732
HBD hemoglobin, delta -2.20695
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.20191
ASCL3 achaete-scute family bHLH transcription factor 3 -2.19848
TEX28 testis expressed 28 -2.19847
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.19787
TRAPPC3 trafficking protein particle complex 3 -2.1973
KIF18B kinesin family member 18B -2.19186
VPS26C VPS26 endosomal protein sorting factor C -2.1918
PLPPR1 phospholipid phosphatase related 1 -2.19083
GCA grancalcin, EF-hand calcium binding protein -2.18738
XPO7 exportin 7 -2.18355
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -2.18343
TMPRSS11E transmembrane protease, serine 11E -2.18262
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.18188
VAV3 vav 3 guanine nucleotide exchange factor -2.18094
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -2.17795
RYR3 ryanodine receptor 3 -2.17764
GATA4 GATA binding protein 4 -2.17735
UNC93A unc-93 homolog A (C. elegans) -2.1771
APEH acylaminoacyl-peptide hydrolase -2.17708
PRKG2 protein kinase, cGMP-dependent, type II -2.17654
PBK PDZ binding kinase -2.17494
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 -2.1723
ZNF236 zinc finger protein 236 -2.17044
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -2.16972
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.16643
TTC28 tetratricopeptide repeat domain 28 -2.16552
LYZ lysozyme -2.16534
PPP1R9A protein phosphatase 1, regulatory subunit 9A -2.16438
UGDH UDP-glucose 6-dehydrogenase -2.16382
HLF hepatic leukemia factor -2.16363
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -2.16286
KHK ketohexokinase (fructokinase) -2.16274
ORM1 orosomucoid 1 -2.15802
SGCE sarcoglycan, epsilon -2.15584
APOE apolipoprotein E -2.15232
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.15194
VRK1 vaccinia related kinase 1 -2.15018
ZNF460 zinc finger protein 460 -2.14974
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.14894
ASXL3 additional sex combs like transcriptional regulator 3 -2.14764
CPVL carboxypeptidase, vitellogenic-like -2.14683
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 -2.14535
PLA2R1 phospholipase A2 receptor 1, 180kDa -2.14521
GNRHR gonadotropin-releasing hormone receptor -2.14446
DEPDC1 DEP domain containing 1 -2.14348
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.13884
PRUNE1 prune exopolyphosphatase 1 -2.13713
MYO1D myosin ID -2.13668
CCDC170 coiled-coil domain containing 170 -2.13551
TMEM176B transmembrane protein 176B -2.13486
ECSIT ECSIT signalling integrator -2.13439
SUSD5 sushi domain containing 5 -2.13411
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -2.13384
EIF2D eukaryotic translation initiation factor 2D -2.13327
AVPR1B arginine vasopressin receptor 1B -2.13318
ADAMTSL3 ADAMTS-like 3 -2.13309
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -2.12984
ZBTB38 zinc finger and BTB domain containing 38 -2.12794
EXOSC5 exosome component 5 -2.12689
NCF4 neutrophil cytosolic factor 4, 40kDa -2.12571
PFAS phosphoribosylformylglycinamidine synthase -2.12447
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.12333
MYO5C myosin VC -2.1219
PIGU phosphatidylinositol glycan anchor biosynthesis, class U -2.12154
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -2.12122
TMPRSS5 transmembrane protease, serine 5 -2.12084
SLC35A5 solute carrier family 35, member A5 -2.11913
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 -2.11878
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -2.11775
PCDHGA10 protocadherin gamma subfamily A, 10 -2.11744
PRSS2 protease, serine, 2 (trypsin 2) -2.11659
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.11534
VIL1 villin 1 -2.11517
NOX1 NADPH oxidase 1 -2.11153
PTPRK protein tyrosine phosphatase, receptor type, K -2.11135
ZFP2 ZFP2 zinc finger protein -2.11107
DHFR dihydrofolate reductase -2.11077
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.1104
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.10989
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.10885
ATL2 atlastin GTPase 2 -2.10861
CHMP6 charged multivesicular body protein 6 -2.10697
TMOD2 tropomodulin 2 (neuronal) -2.10642
PEAK1 pseudopodium-enriched atypical kinase 1 -2.10545
GSTCD glutathione S-transferase, C-terminal domain containing -2.10504
PALS1 protein associated with LIN7 1, MAGUK p55 family member -2.10454
ZNF443 zinc finger protein 443 -2.10428
BHMT betaine--homocysteine S-methyltransferase -2.10258
ADGRL3 adhesion G protein-coupled receptor L3 -2.10246
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -2.10016
TMEM176A transmembrane protein 176A -2.09975
GASK1B golgi associated kinase 1B -2.09816
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -2.0981
ZNF83 zinc finger protein 83 -2.09807
SEPHS1 selenophosphate synthetase 1 -2.0974
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.09718
CA5A carbonic anhydrase VA, mitochondrial -2.09663
SLITRK2 SLIT and NTRK-like family, member 2 -2.09636
KRT33B keratin 33B, type I -2.09558
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.09286
TEDC2 tubulin epsilon and delta complex 2 -2.09257
ATP10A ATPase, class V, type 10A -2.09051
PLXDC2 plexin domain containing 2 -2.09031
LECT2 leukocyte cell-derived chemotaxin 2 -2.08911
MACROD1 MACRO domain containing 1 -2.08477
TBCE tubulin folding cofactor E -2.08417
CARM1 coactivator-associated arginine methyltransferase 1 -2.08285
KRT76 keratin 76, type II -2.08192
CLDN16 claudin 16 -2.08104
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -2.08102
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.07985
ATF6 activating transcription factor 6 -2.07873
RTRAF RNA transcription, translation and transport factor -2.07823
LATS1 large tumor suppressor kinase 1 -2.0774
AIG1 androgen-induced 1 -2.07587
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.07524
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -2.0715
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough -2.07124
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.0708
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.06904
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.06891
NOVA1 neuro-oncological ventral antigen 1 -2.06818
APOC2 apolipoprotein C-II -2.06778
ZIC4 Zic family member 4 -2.0666
TNIK TRAF2 and NCK interacting kinase -2.06386
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -2.06349
SOX5 SRY (sex determining region Y)-box 5 -2.06265
FNBP1L formin binding protein 1-like -2.05999
SUOX sulfite oxidase -2.05971
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.05716
PF4V1 platelet factor 4 variant 1 -2.0567
MOCS2 molybdenum cofactor synthesis 2 -2.05518
NIPAL2 NIPA-like domain containing 2 -2.05469
NCAM2 neural cell adhesion molecule 2 -2.05436
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -2.05289
TK1 thymidine kinase 1, soluble -2.05279
BRD7 bromodomain containing 7 -2.05228
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.04936
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.0482
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.04762
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -2.04561
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.04526
FAM162A family with sequence similarity 162, member A -2.04192
NT5DC2 5'-nucleotidase domain containing 2 -2.0381
FAM184A family with sequence similarity 184, member A -2.03709
CDO1 cysteine dioxygenase type 1 -2.03704
ECEL1 endothelin converting enzyme-like 1 -2.03626
ASB4 ankyrin repeat and SOCS box containing 4 -2.03554
FOS FBJ murine osteosarcoma viral oncogene homolog -2.03466
TRIM58 tripartite motif containing 58 -2.03402
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.03356
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -2.03239
TFF2 trefoil factor 2 -2.03148
RAPSN receptor-associated protein of the synapse -2.02882
SNX5 sorting nexin 5 -2.0277
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -2.02724
LRRC31 leucine rich repeat containing 31 -2.02531
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 -2.02321
LUZP2 leucine zipper protein 2 -2.0229
ZMYM3 zinc finger, MYM-type 3 -2.0225
BCL2L14 BCL2-like 14 (apoptosis facilitator) -2.02034
MEX3D mex-3 RNA binding family member D -2.0201
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.01945
CFI complement factor I -2.0186
VAMP5 vesicle-associated membrane protein 5 -2.0181
TMPRSS6 transmembrane protease, serine 6 -2.01673
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) -2.0156
ZNF480 zinc finger protein 480 -2.01513
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.01354
IMPACT impact RWD domain protein -2.01352
MARCHF1 membrane associated ring-CH-type finger 1 -2.01215
TNS3 tensin 3 -2.01201
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -2.01155
EXOC5 exocyst complex component 5 -2.0112
DET1 de-etiolated homolog 1 (Arabidopsis) -2.0103
VN1R1 vomeronasal 1 receptor 1 -2.00883
ANGPTL3 angiopoietin-like 3 -2.00803
FTCD formimidoyltransferase cyclodeaminase -2.00685
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.00575
RUVBL1 RuvB-like AAA ATPase 1 -2.0054
MSMO1 methylsterol monooxygenase 1 -2.00427
EVI5 ecotropic viral integration site 5 -2.00202
MAPK6 mitogen-activated protein kinase 6 -2.00184