CRCGN014_HEPG2_24H:H04 Gene Set
Genes
53 genes differentially expressed following the CRCGN014_HEPG2_24H:H04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.90212
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.28562
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
5.21799
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
4.96888
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
4.17334
|
|
MYLK
|
myosin light chain kinase
|
3.88202
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.79821
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.54708
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.5242
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.9507
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.84921
|
|
EPHB2
|
EPH receptor B2
|
2.83226
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.55421
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.45143
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.39697
|
|
KDM1A
|
lysine (K)-specific demethylase 1A
|
2.26029
|
|
CYCS
|
cytochrome c, somatic
|
2.24575
|
|
TMEM176A
|
transmembrane protein 176A
|
2.19892
|
|
NENF
|
neudesin neurotrophic factor
|
2.18667
|
|
CHN1
|
chimerin 1
|
2.17268
|
|
LRRC20
|
leucine rich repeat containing 20
|
2.15567
|
|
FOXO3
|
forkhead box O3
|
2.13102
|
|
TMEM176B
|
transmembrane protein 176B
|
2.1021
|
|
SNTA1
|
syntrophin, alpha 1
|
2.06208
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.04938
|
|
ECHDC2
|
enoyl CoA hydratase domain containing 2
|
2.04104
|
|
STIMATE
|
STIM activating enhancer
|
2.01213
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.71504
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.87809
|
|
CCNB2
|
cyclin B2
|
-5.09134
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.59111
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-4.10034
|
|
GOLT1B
|
golgi transport 1B
|
-3.86339
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.73892
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.69286
|
|
LDHD
|
lactate dehydrogenase D
|
-3.27157
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.25486
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.21239
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.12918
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.96007
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.72316
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.53694
|
|
MMP2
|
matrix metallopeptidase 2
|
-2.50734
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.25268
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.23899
|
|
ACLY
|
ATP citrate lyase
|
-2.21732
|
|
ZNF514
|
zinc finger protein 514
|
-2.2135
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.1576
|
|
GNAS
|
GNAS complex locus
|
-2.12996
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.0893
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.07804
|
|
PGM1
|
phosphoglucomutase 1
|
-2.07299
|
|
PARP6
|
poly (ADP-ribose) polymerase family, member 6
|
-2.04952
|
