CRCGN014_HEPG2_24H:H06 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.07345
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.75355
|
|
GPATCH8
|
G patch domain containing 8
|
3.13128
|
|
TRAM2
|
translocation associated membrane protein 2
|
2.50687
|
|
EPHA3
|
EPH receptor A3
|
2.19246
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.16958
|
|
DCXR
|
dicarbonyl/L-xylulose reductase
|
2.15312
|
|
KLHL9
|
kelch-like family member 9
|
2.13519
|
|
PMM2
|
phosphomannomutase 2
|
2.12799
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.10655
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.06191
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.93791
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.14628
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.06906
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.05349
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.87079
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.79585
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.60538
|
|
LDHD
|
lactate dehydrogenase D
|
-4.58846
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.14046
|
|
COG7
|
component of oligomeric golgi complex 7
|
-4.10099
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.91973
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.63057
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.48154
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.77756
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.67008
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.59436
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.55103
|
|
TLR4
|
toll-like receptor 4
|
-2.48818
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.36864
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.3453
|
|
CERT1
|
ceramide transporter 1
|
-2.29853
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.14971
|
|
MGMT
|
O-6-methylguanine-DNA methyltransferase
|
-2.10136
|
|
SNCB
|
synuclein, beta
|
-2.04635
|
|
VPS35
|
vacuolar protein sorting 35 homolog (S. cerevisiae)
|
-2.0268
|
