CRCGN014_HEPG2_24H:H07 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_24H:H07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
7.10011
|
|
CBR3
|
carbonyl reductase 3
|
6.39021
|
|
HMOX1
|
heme oxygenase 1
|
5.43906
|
|
LCN2
|
lipocalin 2
|
4.50648
|
|
TXNRD1
|
thioredoxin reductase 1
|
4.47582
|
|
ABHD4
|
abhydrolase domain containing 4
|
4.41957
|
|
CTSL
|
cathepsin L
|
3.97287
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.93244
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
3.83916
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.51965
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
3.49884
|
|
UBQLN2
|
ubiquilin 2
|
3.02927
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.01351
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.00207
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.94448
|
|
KEAP1
|
kelch-like ECH-associated protein 1
|
2.6306
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.61869
|
|
RRAGA
|
Ras-related GTP binding A
|
2.52477
|
|
FZD7
|
frizzled class receptor 7
|
2.49839
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.49811
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.40502
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.39491
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
2.28521
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
2.25222
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.13893
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.12886
|
|
IDE
|
insulin-degrading enzyme
|
2.11476
|
|
BLMH
|
bleomycin hydrolase
|
2.08147
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.0077
|
|
NUP85
|
nucleoporin 85kDa
|
-4.12388
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.50514
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.29756
|
|
CD320
|
CD320 molecule
|
-3.18249
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.85887
|
|
CCNB2
|
cyclin B2
|
-2.65643
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.41315
|
|
BMP4
|
bone morphogenetic protein 4
|
-2.38351
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.37923
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.2951
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.2612
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.22921
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.18143
|
|
PPP1R3C
|
protein phosphatase 1, regulatory subunit 3C
|
-2.16314
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.15297
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
-2.10641
|
|
DCK
|
deoxycytidine kinase
|
-2.06994
|
