| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nifedipine 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN014_HEPG2_24H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.93934 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.99218 |
| MYLK | myosin light chain kinase | 3.65658 |
| CHMP6 | charged multivesicular body protein 6 | 3.55073 |
| GPATCH8 | G patch domain containing 8 | 3.44568 |
| MOK | MOK protein kinase | 3.44525 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.43462 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.18921 |
| E2F2 | E2F transcription factor 2 | 3.14715 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.13674 |
| LSR | lipolysis stimulated lipoprotein receptor | 3.10191 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.99785 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.98551 |
| UBQLN2 | ubiquilin 2 | 2.98015 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.96716 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.8228 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.77463 |
| STK10 | serine/threonine kinase 10 | 2.58847 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.55843 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.54672 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.53138 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.41332 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.40856 |
| NENF | neudesin neurotrophic factor | 2.40227 |
| JADE2 | jade family PHD finger 2 | 2.35161 |
| CEP57 | centrosomal protein 57kDa | 2.20249 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 2.00379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.35174 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -6.78554 |
| CCNB2 | cyclin B2 | -4.53728 |
| GNAS | GNAS complex locus | -4.45541 |
| ADI1 | acireductone dioxygenase 1 | -4.32453 |
| GOLT1B | golgi transport 1B | -4.23138 |
| DSG2 | desmoglein 2 | -3.75936 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.66404 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.45646 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.43398 |
| DNM1L | dynamin 1-like | -3.29058 |
| CCDC86 | coiled-coil domain containing 86 | -3.0681 |
| ENOPH1 | enolase-phosphatase 1 | -2.99392 |
| CD320 | CD320 molecule | -2.96851 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.92489 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.85395 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.65954 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.65198 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | -2.54914 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.45632 |
| SNX11 | sorting nexin 11 | -2.28317 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | -2.26181 |
| EGF | epidermal growth factor | -2.25317 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.24662 |
| RCAN3 | RCAN family member 3 | -2.22535 |
| VTA1 | vesicle (multivesicular body) trafficking 1 | -2.21877 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.17353 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -2.1097 |
