CRCGN014_HEPG2_24H:H14 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
4.09638
|
|
UBQLN2
|
ubiquilin 2
|
3.32772
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.18936
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.06247
|
|
NOTCH1
|
notch 1
|
3.02726
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.01099
|
|
MAP7
|
microtubule-associated protein 7
|
2.52854
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.44099
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.38111
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.30785
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.26958
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.26424
|
|
PRR15L
|
proline rich 15-like
|
2.20807
|
|
TRIB3
|
tribbles pseudokinase 3
|
2.15002
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-4.83576
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.7729
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.5794
|
|
CD320
|
CD320 molecule
|
-3.32363
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.3078
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.16084
|
|
CDC25B
|
cell division cycle 25B
|
-2.93463
|
|
LYPLA1
|
lysophospholipase I
|
-2.80613
|
|
ZNF586
|
zinc finger protein 586
|
-2.71115
|
|
LDHD
|
lactate dehydrogenase D
|
-2.70019
|
|
TEX10
|
testis expressed 10
|
-2.25839
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.24507
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.22757
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.22332
|
|
SNX11
|
sorting nexin 11
|
-2.21695
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.16521
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.0783
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.01765
|
|
CCNB2
|
cyclin B2
|
-2.0085
|
