CRCGN014_HEPG2_24H:H17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzoic acid, sodium 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN014_HEPG2_24H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.73788
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 4.45697
FZD7 frizzled class receptor 7 4.07723
PNKP polynucleotide kinase 3'-phosphatase 4.00364
ABHD6 abhydrolase domain containing 6 3.83806
NOTCH1 notch 1 3.29847
CHN1 chimerin 1 3.04493
CDPF1 cysteine-rich, DPF motif domain containing 1 3.02122
PLSCR3 phospholipid scramblase 3 2.97494
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.97174
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.3101
UFM1 ubiquitin-fold modifier 1 2.29249
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.2117
CYCS cytochrome c, somatic 2.07812

decreased expression

Symbol Name Standardized Value
DNM1L dynamin 1-like -4.85186
THAP11 THAP domain containing 11 -4.29849
LDHD lactate dehydrogenase D -4.13806
LAP3 leucine aminopeptidase 3 -3.77342
CCNB1 cyclin B1 -3.68758
GNAS GNAS complex locus -2.96132
PECR peroxisomal trans-2-enoyl-CoA reductase -2.7948
TLR4 toll-like receptor 4 -2.65853
REEP5 receptor accessory protein 5 -2.29395
OXA1L oxidase (cytochrome c) assembly 1-like -2.28735
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.10718
ADGRG6 adhesion G protein-coupled receptor G6 -2.02812