CRCGN014_HEPG2_24H:H19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mepyramine 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the CRCGN014_HEPG2_24H:H19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 8.01464
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.70614
SNAP25 synaptosomal-associated protein, 25kDa 3.99734
UBQLN2 ubiquilin 2 3.67696
PPARG peroxisome proliferator-activated receptor gamma 3.30314
RPP38 ribonuclease P/MRP 38kDa subunit 3.21304
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.08485
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 2.99745
CHN1 chimerin 1 2.83366
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.68229
GATA3 GATA binding protein 3 2.61259
DIPK1A divergent protein kinase domain 1A 2.58741
FZD7 frizzled class receptor 7 2.50293
DENND2D DENN/MADD domain containing 2D 2.475
FAIM Fas apoptotic inhibitory molecule 2.46793
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.33333
DMTF1 cyclin D binding myb-like transcription factor 1 2.32749
BPHL biphenyl hydrolase-like (serine hydrolase) 2.32647
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.31381
CEP57 centrosomal protein 57kDa 2.21859
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.1428
ACYP1 acylphosphatase 1, erythrocyte (common) type 2.12247
PLSCR1 phospholipid scramblase 1 2.10469

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.86946
LDHD lactate dehydrogenase D -7.43824
ZNF586 zinc finger protein 586 -6.45815
CCNB2 cyclin B2 -5.34299
DNM1L dynamin 1-like -4.6791
TLCD3A TLC domain containing 3A -4.43333
TP53BP2 tumor protein p53 binding protein 2 -4.1076
TRIB3 tribbles pseudokinase 3 -3.55768
RGS2 regulator of G-protein signaling 2 -3.47925
UGDH UDP-glucose 6-dehydrogenase -3.20012
EGF epidermal growth factor -2.90522
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.74012
MAPK13 mitogen-activated protein kinase 13 -2.55061
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.31397
ATF5 activating transcription factor 5 -2.31137
SNX11 sorting nexin 11 -2.21363
TES testin LIM domain protein -2.18303
C5 complement component 5 -2.14737
OXA1L oxidase (cytochrome c) assembly 1-like -2.12351
TXNDC9 thioredoxin domain containing 9 -2.11588
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.10012
CHODL chondrolectin -2.03991
GDF15 growth differentiation factor 15 -2.00877