CRCGN014_HEPG2_24H:H21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description auramine-o 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

435 genes differentially expressed following the CRCGN014_HEPG2_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP1 inositol polyphosphate-1-phosphatase 8.18237
CCDC92 coiled-coil domain containing 92 8.12737
SQOR sulfide quinone oxidoreductase 7.53007
CNPY3 canopy FGF signaling regulator 3 7.15564
GFOD1 glucose-fructose oxidoreductase domain containing 1 6.09382
LRP10 low density lipoprotein receptor-related protein 10 6.01734
TIMP2 TIMP metallopeptidase inhibitor 2 5.7484
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.36837
DDIT4 DNA-damage-inducible transcript 4 5.07791
IGFBP3 insulin-like growth factor binding protein 3 5.06728
MICALL1 MICAL-like 1 4.99511
NPC1 Niemann-Pick disease, type C1 4.981
STAP2 signal transducing adaptor family member 2 4.78231
UBQLN2 ubiquilin 2 4.77732
STX1A syntaxin 1A (brain) 4.67285
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.6419
ZFP36 ZFP36 ring finger protein 4.42206
SHB Src homology 2 domain containing adaptor protein B 4.41186
ABHD4 abhydrolase domain containing 4 4.36273
C2CD2 C2 calcium-dependent domain containing 2 4.2351
CASC3 cancer susceptibility candidate 3 4.15202
PPARG peroxisome proliferator-activated receptor gamma 4.1182
LOXL1 lysyl oxidase-like 1 3.9528
CCL2 chemokine (C-C motif) ligand 2 3.94234
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.85754
PRAF2 PRA1 domain family, member 2 3.74532
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.63858
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.50547
CSNK1E casein kinase 1, epsilon 3.43836
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.4377
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.34864
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.33973
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.33262
GPC1 glypican 1 3.30693
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.28658
FOSL1 FOS-like antigen 1 3.28438
LCN2 lipocalin 2 3.25421
KLHL21 kelch-like family member 21 3.23741
H2BC21 H2B clustered histone 21 3.21004
CLIP3 CAP-GLY domain containing linker protein 3 3.20582
SARS1 seryl-tRNA synthetase 1 3.19662
ZBTB35 zinc finger and BTB domain containing 35 3.10746
ALAS1 5'-aminolevulinate synthase 1 3.09116
NVL nuclear VCP-like 3.08673
LYN LYN proto-oncogene, Src family tyrosine kinase 3.06358
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.05978
ST18 suppression of tumorigenicity 18, zinc finger 3.05379
CSRNP2 cysteine-serine-rich nuclear protein 2 3.022
MTERF3 mitochondrial transcription termination factor 3 2.95675
VAT1 vesicle amine transport 1 2.92332
TRIM13 tripartite motif containing 13 2.90392
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.90255
YIPF3 Yip1 domain family, member 3 2.8742
NANOS3 nanos homolog 3 (Drosophila) 2.86095
GADD45A growth arrest and DNA-damage-inducible, alpha 2.85892
IER3 immediate early response 3 2.84979
STN1 STN1 subunit of CST complex 2.84247
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.82175
TRAPPC6A trafficking protein particle complex 6A 2.82164
TSC22D3 TSC22 domain family, member 3 2.80634
GSTZ1 glutathione S-transferase zeta 1 2.8013
IPO13 importin 13 2.79331
CLOCK clock circadian regulator 2.78773
TNIP1 TNFAIP3 interacting protein 1 2.77943
SAYSD1 SAYSVFN motif domain containing 1 2.74698
PYGB phosphorylase, glycogen; brain 2.74218
NOTCH1 notch 1 2.72902
GARS1 glycyl-tRNA synthetase 1 2.72712
DDB2 damage-specific DNA binding protein 2, 48kDa 2.71616
AARS1 alanyl-tRNA synthetase 1 2.71134
BAMBI BMP and activin membrane-bound inhibitor 2.71055
TESK1 testis-specific kinase 1 2.70644
GTPBP2 GTP binding protein 2 2.6682
TERF2IP telomeric repeat binding factor 2, interacting protein 2.66132
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.66025
NUP58 nucleoporin 58 2.65094
ANKRD10 ankyrin repeat domain 10 2.64883
MYLK myosin light chain kinase 2.64668
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.64636
TOMM34 translocase of outer mitochondrial membrane 34 2.64166
CYCS cytochrome c, somatic 2.64061
PDLIM1 PDZ and LIM domain 1 2.63512
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.61943
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.56047
PTPN12 protein tyrosine phosphatase, non-receptor type 12 2.55668
GRB10 growth factor receptor-bound protein 10 2.51743
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.51295
DYNLT3 dynein, light chain, Tctex-type 3 2.50804
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.5023
MVP major vault protein 2.49384
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.48675
CAMTA2 calmodulin binding transcription activator 2 2.47337
LARP6 La ribonucleoprotein domain family, member 6 2.47318
PRKCD protein kinase C, delta 2.46735
RUSC2 RUN and SH3 domain containing 2 2.46485
TENT4A terminal nucleotidyltransferase 4A 2.46089
H2BC12 H2B clustered histone 12 2.45762
CLCA4 chloride channel accessory 4 2.45161
PADI2 peptidyl arginine deiminase, type II 2.44576
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.43885
STBD1 starch binding domain 1 2.43459
RRAGC Ras-related GTP binding C 2.40584
TES testin LIM domain protein 2.38663
PTK2 protein tyrosine kinase 2 2.38496
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.38493
EPS8 epidermal growth factor receptor pathway substrate 8 2.36746
ASCC1 activating signal cointegrator 1 complex subunit 1 2.3584
EIF3D eukaryotic translation initiation factor 3, subunit D 2.3455
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.33623
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.33502
CDK7 cyclin-dependent kinase 7 2.33162
JOSD1 Josephin domain containing 1 2.33076
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.32133
SV2A synaptic vesicle glycoprotein 2A 2.31411
RAB33A RAB33A, member RAS oncogene family 2.29884
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.29782
MAP7D1 MAP7 domain containing 1 2.29448
ZYX zyxin 2.29394
HAPLN1 hyaluronan and proteoglycan link protein 1 2.2937
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.29348
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.29175
MACO1 macoilin 1 2.29042
SMIM40 small integral membrane protein 40 2.28431
IQGAP1 IQ motif containing GTPase activating protein 1 2.27907
IL1B interleukin 1, beta 2.27701
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.26809
EIF3L eukaryotic translation initiation factor 3, subunit L 2.26539
LMBRD1 LMBR1 domain containing 1 2.24894
RHOG ras homolog family member G 2.2422
ATF4 activating transcription factor 4 2.2419
SUN2 Sad1 and UNC84 domain containing 2 2.2393
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.23721
CAMLG calcium modulating ligand 2.2349
THBD thrombomodulin 2.22965
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.22926
SDC4 syndecan 4 2.22767
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.22503
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.22127
MXI1 MAX interactor 1, dimerization protein 2.21574
CHN1 chimerin 1 2.21369
LIN37 lin-37 DREAM MuvB core complex component 2.21163
SNX13 sorting nexin 13 2.20808
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.20417
ADORA2B adenosine A2b receptor 2.19588
MRC1 mannose receptor, C type 1 2.19493
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.19371
STX3 syntaxin 3 2.19014
TBCC tubulin folding cofactor C 2.1869
MAPK7 mitogen-activated protein kinase 7 2.18671
PDGFA platelet-derived growth factor alpha polypeptide 2.18453
ADGRG1 adhesion G protein-coupled receptor G1 2.17993
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.17899
EVI2A ecotropic viral integration site 2A 2.17102
CDKL3 cyclin-dependent kinase-like 3 2.16983
CCNA1 cyclin A1 2.16746
PPARD peroxisome proliferator-activated receptor delta 2.15775
TXNRD1 thioredoxin reductase 1 2.15433
FBXO28 F-box protein 28 2.14585
CTSD cathepsin D 2.14501
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.14317
UNC13D unc-13 homolog D (C. elegans) 2.14115
HSPA1A heat shock 70kDa protein 1A 2.14108
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.13987
PTPRK protein tyrosine phosphatase, receptor type, K 2.13781
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.13292
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.12686
INSM1 insulinoma-associated 1 2.12518
HOXD1 homeobox D1 2.1242
ITGA10 integrin, alpha 10 2.11829
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.11552
BAX BCL2-associated X protein 2.11329
DSG2 desmoglein 2 2.11241
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.11034
H2AC6 H2A clustered histone 6 2.10963
MEA1 male-enhanced antigen 1 2.10957
RRAGA Ras-related GTP binding A 2.10193
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.09888
IL37 interleukin 37 2.09826
IER5 immediate early response 5 2.09729
BICRAL BICRA like chromatin remodeling complex associated protein 2.09722
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.09506
STXBP1 syntaxin binding protein 1 2.09176
CALHM2 calcium homeostasis modulator 2 2.08621
TTLL1 tubulin tyrosine ligase-like family member 1 2.08149
HPGDS hematopoietic prostaglandin D synthase 2.07836
RXYLT1 ribitol xylosyltransferase 1 2.07367
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.07216
PORCN porcupine homolog (Drosophila) 2.06893
NGRN neugrin, neurite outgrowth associated 2.06694
EDN1 endothelin 1 2.06445
ANKRD44 ankyrin repeat domain 44 2.06178
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.06177
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.06111
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.05579
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.05509
EAPP E2F-associated phosphoprotein 2.04366
RGS10 regulator of G-protein signaling 10 2.04033
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.03544
BAG6 BCL2-associated athanogene 6 2.03385
APOBR apolipoprotein B receptor 2.03062
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.02669
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.02265
SMNDC1 survival motor neuron domain containing 1 2.0183
FABP2 fatty acid binding protein 2, intestinal 2.01806
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.00629
FICD FIC domain containing 2.00533
CDHR1 cadherin-related family member 1 2.00458
NT5E 5'-nucleotidase, ecto (CD73) 2.00443

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -9.86947
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -9.31688
B4GAT1 beta-1,4-glucuronyltransferase 1 -8.5411
PARP1 poly (ADP-ribose) polymerase 1 -7.2576
ISOC1 isochorismatase domain containing 1 -7.07702
PCCB propionyl CoA carboxylase, beta polypeptide -5.7182
NUP85 nucleoporin 85kDa -5.63609
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.53885
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.51913
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.356
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.27178
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.18034
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.68396
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.65297
BLCAP bladder cancer associated protein -4.49299
TRIB3 tribbles pseudokinase 3 -4.4208
BIRC5 baculoviral IAP repeat containing 5 -4.40985
CCNA2 cyclin A2 -4.29385
ZNF586 zinc finger protein 586 -4.12757
MRPL12 mitochondrial ribosomal protein L12 -4.08812
PROS1 protein S (alpha) -4.03684
MRPS7 mitochondrial ribosomal protein S7 -3.97576
HMGA2 high mobility group AT-hook 2 -3.94716
INTS3 integrator complex subunit 3 -3.94116
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.79206
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.78812
CDK1 cyclin-dependent kinase 1 -3.7777
GLOD4 glyoxalase domain containing 4 -3.76691
STMN1 stathmin 1 -3.758
PGAM4 phosphoglycerate mutase family member 4 -3.71305
SKIC8 SKI8 subunit of superkiller complex -3.68906
AKAP8 A kinase (PRKA) anchor protein 8 -3.66938
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.51354
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.49987
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.49304
RUVBL1 RuvB-like AAA ATPase 1 -3.49293
PSRC1 proline/serine-rich coiled-coil 1 -3.40291
NT5DC2 5'-nucleotidase domain containing 2 -3.4027
HAT1 histone acetyltransferase 1 -3.3878
MYCBP MYC binding protein -3.38056
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.37488
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.34435
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.33816
CD320 CD320 molecule -3.31765
RSU1 Ras suppressor protein 1 -3.31304
HMOX1 heme oxygenase 1 -3.19784
ITGB1BP1 integrin beta 1 binding protein 1 -3.19643
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.18265
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.18162
MCM10 minichromosome maintenance complex component 10 -3.181
PDGFRL platelet-derived growth factor receptor-like -3.16099
TFDP1 transcription factor Dp-1 -3.14859
PGRMC1 progesterone receptor membrane component 1 -3.14727
AMDHD2 amidohydrolase domain containing 2 -3.14205
CHMP6 charged multivesicular body protein 6 -3.1392
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -3.13841
PRCP prolylcarboxypeptidase (angiotensinase C) -3.1169
NUCB2 nucleobindin 2 -3.11318
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.10409
MRPL58 mitochondrial ribosomal protein L58 -3.0626
CDC6 cell division cycle 6 -3.02738
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.98405
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.96201
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.95542
TOP2A topoisomerase (DNA) II alpha 170kDa -2.95388
SELENOT selenoprotein T -2.95386
RAB8A RAB8A, member RAS oncogene family -2.92464
PDIA6 protein disulfide isomerase family A, member 6 -2.91445
GTF2A2 general transcription factor IIA, 2, 12kDa -2.91379
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.90338
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.88812
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.87514
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.86935
PGM1 phosphoglucomutase 1 -2.86134
XPO1 exportin 1 -2.85875
WASHC4 WASH complex subunit 4 -2.83036
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.82342
TUBB6 tubulin, beta 6 class V -2.81623
AURKB aurora kinase B -2.80833
ASF1B anti-silencing function 1B histone chaperone -2.79971
HYOU1 hypoxia up-regulated 1 -2.79376
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.78157
BMP4 bone morphogenetic protein 4 -2.75311
MELK maternal embryonic leucine zipper kinase -2.73959
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.7298
TK1 thymidine kinase 1, soluble -2.70507
PEG10 paternally expressed 10 -2.6808
KHK ketohexokinase (fructokinase) -2.6693
ARF5 ADP-ribosylation factor 5 -2.65569
LBR lamin B receptor -2.65501
SFXN1 sideroflexin 1 -2.6404
ATP5MF ATP synthase membrane subunit f -2.63347
TRIP13 thyroid hormone receptor interactor 13 -2.6321
CHMP4B charged multivesicular body protein 4B -2.62883
NUP107 nucleoporin 107kDa -2.58578
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.57228
KIF11 kinesin family member 11 -2.5655
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.55787
LYRM1 LYR motif containing 1 -2.54481
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.54228
SORD sorbitol dehydrogenase -2.53101
ACAA1 acetyl-CoA acyltransferase 1 -2.52523
OIP5 Opa interacting protein 5 -2.52159
BLMH bleomycin hydrolase -2.52013
RNASE7 ribonuclease, RNase A family, 7 -2.51566
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.51376
PBK PDZ binding kinase -2.51161
CHEK2 checkpoint kinase 2 -2.50505
NLRP2B NLR family pyrin domain containing 2B -2.49864
THAP11 THAP domain containing 11 -2.49784
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.49389
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.49388
GLRX5 glutaredoxin 5 -2.48806
PLK1 polo-like kinase 1 -2.48647
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.48038
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.47676
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.47608
SRSF3 serine/arginine-rich splicing factor 3 -2.46013
ANKFY1 ankyrin repeat and FYVE domain containing 1 -2.45334
ELAVL1 ELAV like RNA binding protein 1 -2.45083
UBE2M ubiquitin-conjugating enzyme E2M -2.43911
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -2.43496
NENF neudesin neurotrophic factor -2.42956
SHCBP1 SHC SH2-domain binding protein 1 -2.42595
NEK4 NIMA-related kinase 4 -2.42501
FBLN5 fibulin 5 -2.41794
NNT nicotinamide nucleotide transhydrogenase -2.41547
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.41415
UBL5 ubiquitin-like 5 -2.41044
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.40885
CDC20 cell division cycle 20 -2.40074
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.40015
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.39681
RPA3 replication protein A3, 14kDa -2.39443
CDK4 cyclin-dependent kinase 4 -2.39125
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.38915
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.38905
ATP5PD ATP synthase peripheral stalk subunit d -2.38829
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.38612
C2CD5 C2 calcium-dependent domain containing 5 -2.38318
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.37555
HEATR1 HEAT repeat containing 1 -2.36615
CDK6 cyclin-dependent kinase 6 -2.36371
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -2.36082
ERH enhancer of rudimentary homolog (Drosophila) -2.36028
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.35478
PHB1 prohibitin 1 -2.35438
SPPL2A signal peptide peptidase like 2A -2.35325
KIF4A kinesin family member 4A -2.34349
FANCI Fanconi anemia, complementation group I -2.34031
VRK1 vaccinia related kinase 1 -2.33739
FAM111A family with sequence similarity 111, member A -2.32974
BAHCC1 BAH domain and coiled-coil containing 1 -2.3277
CEP43 centrosomal protein 43 -2.32504
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -2.32183
MRPL19 mitochondrial ribosomal protein L19 -2.31733
SRSF2 serine/arginine-rich splicing factor 2 -2.30111
CRTAP cartilage associated protein -2.29499
DERA deoxyribose-phosphate aldolase (putative) -2.29018
TATDN2 TatD DNase domain containing 2 -2.28432
PDIA5 protein disulfide isomerase family A, member 5 -2.27969
PRPF4 pre-mRNA processing factor 4 -2.2794
PDF peptide deformylase (mitochondrial) -2.27851
TTC27 tetratricopeptide repeat domain 27 -2.27762
SLIRP SRA stem-loop interacting RNA binding protein -2.27628
SCARB1 scavenger receptor class B, member 1 -2.27097
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.26406
ABHD3 abhydrolase domain containing 3 -2.24418
COL5A1 collagen, type V, alpha 1 -2.24389
MAT2A methionine adenosyltransferase II, alpha -2.23226
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.23034
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.22364
TMEM14A transmembrane protein 14A -2.22335
ISOC2 isochorismatase domain containing 2 -2.22072
CDK2 cyclin-dependent kinase 2 -2.21863
FIG4 FIG4 phosphoinositide 5-phosphatase -2.21845
ALAD aminolevulinate dehydratase -2.21679
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.21535
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.20811
TOP2B topoisomerase (DNA) II beta 180kDa -2.20809
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.20047
TMEM109 transmembrane protein 109 -2.19914
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.19867
ADI1 acireductone dioxygenase 1 -2.18059
PEPD peptidase D -2.17623
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.16964
FUS FUS RNA binding protein -2.16902
LAGE3 L antigen family, member 3 -2.1682
SUMO4 small ubiquitin-like modifier 4 -2.16641
MTCH2 mitochondrial carrier 2 -2.16002
COG4 component of oligomeric golgi complex 4 -2.15644
TMPO thymopoietin -2.15322
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.14644
UBE2C ubiquitin-conjugating enzyme E2C -2.13644
ORC6 origin recognition complex, subunit 6 -2.12996
PRUNE1 prune exopolyphosphatase 1 -2.1184
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.11387
MSH2 mutS homolog 2 -2.11166
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.10922
PRMT1 protein arginine methyltransferase 1 -2.10442
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.10266
STAT1 signal transducer and activator of transcription 1, 91kDa -2.09786
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.08582
ECT2 epithelial cell transforming 2 -2.08517
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -2.08002
SIVA1 SIVA1, apoptosis-inducing factor -2.07413
ERCC6L excision repair cross-complementation group 6-like -2.07188
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.06693
IFT81 intraflagellar transport 81 -2.06233
KIF15 kinesin family member 15 -2.05922
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.05825
ZNF107 zinc finger protein 107 -2.05358
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.05076
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.0478
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.04171
HADH hydroxyacyl-CoA dehydrogenase -2.03758
ICAM3 intercellular adhesion molecule 3 -2.02999
MLEC malectin -2.02615
NFIL3 nuclear factor, interleukin 3 regulated -2.02335
FKBP3 FK506 binding protein 3, 25kDa -2.02118
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.02086
BANF1 barrier to autointegration factor 1 -2.01353
PRR7 proline rich 7 (synaptic) -2.01063
CCN2 cellular communication network factor 2 -2.00877
UBE2N ubiquitin-conjugating enzyme E2N -2.00685
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.001
MRPL42 mitochondrial ribosomal protein L42 -2.00095