| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimpylate 20.91 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN014_HEPG2_24H:H22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 6.25038 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.64679 |
| PTK2 | protein tyrosine kinase 2 | 3.64327 |
| STK10 | serine/threonine kinase 10 | 3.49284 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.44687 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.42536 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.41316 |
| UBQLN2 | ubiquilin 2 | 3.33906 |
| CYCS | cytochrome c, somatic | 3.33052 |
| MCOLN1 | mucolipin 1 | 3.32238 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.18807 |
| EGF | epidermal growth factor | 3.17713 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.06645 |
| EVL | Enah/Vasp-like | 3.01083 |
| H2BC12 | H2B clustered histone 12 | 2.9388 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.86518 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.80467 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.64888 |
| AOC3 | amine oxidase, copper containing 3 | 2.29354 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.2425 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 2.2223 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.20331 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 2.15379 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.08272 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.07066 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -6.69316 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.15678 |
| ZNF586 | zinc finger protein 586 | -5.00732 |
| CDC20 | cell division cycle 20 | -3.58815 |
| UBE3C | ubiquitin protein ligase E3C | -3.45697 |
| TLR4 | toll-like receptor 4 | -3.44703 |
| ADI1 | acireductone dioxygenase 1 | -3.39309 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.29979 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.27398 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.26842 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.25317 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.22165 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.21734 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.13875 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.97433 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.94795 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.73827 |
| HYOU1 | hypoxia up-regulated 1 | -2.66144 |
| CCNB2 | cyclin B2 | -2.57147 |
| TUBB6 | tubulin, beta 6 class V | -2.56006 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.53877 |
| RPS5 | ribosomal protein S5 | -2.51731 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.48923 |
| SNX11 | sorting nexin 11 | -2.39389 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.33147 |
| ICAM3 | intercellular adhesion molecule 3 | -2.16783 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.15537 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.1365 |
| NUP62 | nucleoporin 62kDa | -2.07978 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.06881 |
| CAB39 | calcium binding protein 39 | -2.06301 |
| UIMC1 | ubiquitin interaction motif containing 1 | -2.03152 |
| NAALADL1 | N-acetylated alpha-linked acidic dipeptidase-like 1 | -2.0112 |
