CRCGN014_HEPG2_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description etodolac 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

380 genes differentially expressed following the CRCGN014_HEPG2_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 10.0
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 6.44682
GPATCH8 G patch domain containing 8 5.48261
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.47744
PHKG2 phosphorylase kinase, gamma 2 (testis) 5.1011
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.98674
EPHB2 EPH receptor B2 4.95582
PMM2 phosphomannomutase 2 4.87777
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.87461
CXCL2 chemokine (C-X-C motif) ligand 2 4.7857
STIMATE STIM activating enhancer 4.37859
STAP2 signal transducing adaptor family member 2 4.34147
IDE insulin-degrading enzyme 4.28678
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.26196
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 4.19212
HOXA10 homeobox A10 4.04392
STK10 serine/threonine kinase 10 4.00365
PEX11A peroxisomal biogenesis factor 11 alpha 3.93329
AMDHD2 amidohydrolase domain containing 2 3.80136
CBR1 carbonyl reductase 1 3.76551
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.7525
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.63209
MAP7 microtubule-associated protein 7 3.61675
CHMP6 charged multivesicular body protein 6 3.3442
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.23402
ABHD6 abhydrolase domain containing 6 3.14627
GARRE1 granule associated Rac and RHOG effector 1 3.10329
GSTZ1 glutathione S-transferase zeta 1 3.0932
PPARG peroxisome proliferator-activated receptor gamma 2.97531
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.97251
TCTN3 tectonic family member 3 2.96798
JADE2 jade family PHD finger 2 2.96321
MBNL3 muscleblind-like splicing regulator 3 2.94743
PAGE1 P antigen family, member 1 (prostate associated) 2.94571
EN2 engrailed homeobox 2 2.9217
STXBP2 syntaxin binding protein 2 2.91743
SATB1 SATB homeobox 1 2.90448
ZNF589 zinc finger protein 589 2.894
POU2F1 POU class 2 homeobox 1 2.83839
CNTN2 contactin 2 (axonal) 2.82373
TIAM1 T-cell lymphoma invasion and metastasis 1 2.80149
MTA2 metastasis associated 1 family, member 2 2.80069
POMT2 protein-O-mannosyltransferase 2 2.78352
LYN LYN proto-oncogene, Src family tyrosine kinase 2.77406
CHN1 chimerin 1 2.76454
HPR haptoglobin-related protein 2.76412
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.68541
BAAT bile acid CoA:amino acid N-acyltransferase 2.67781
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.67577
ADM2 adrenomedullin 2 2.66909
TRAIP TRAF interacting protein 2.6666
CLDN9 claudin 9 2.66523
TATDN2 TatD DNase domain containing 2 2.63582
TBP TATA box binding protein 2.62474
MAST2 microtubule associated serine/threonine kinase 2 2.62204
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.61866
DGKQ diacylglycerol kinase, theta 110kDa 2.6144
OVOL3 ovo-like zinc finger 3 2.60936
CNOT9 CCR4-NOT transcription complex subunit 9 2.60402
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 2.60065
ZDHHC14 zinc finger, DHHC-type containing 14 2.59513
GNRH2 gonadotropin-releasing hormone 2 2.58836
S100PBP S100P binding protein 2.58266
CDX4 caudal type homeobox 4 2.58224
FBXW10B F-box and WD repeat domain containing 10B 2.57197
FGF18 fibroblast growth factor 18 2.56954
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.56407
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.55703
INSL6 insulin-like 6 2.55626
RXYLT1 ribitol xylosyltransferase 1 2.55544
UBE2O ubiquitin-conjugating enzyme E2O 2.55506
ELL2 elongation factor, RNA polymerase II, 2 2.55418
FOXA2 forkhead box A2 2.55079
FAM120C family with sequence similarity 120C 2.54703
LHX1 LIM homeobox 1 2.54558
ACOT8 acyl-CoA thioesterase 8 2.54177
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.54126
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.52871
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.51719
DCAF4 DDB1 and CUL4 associated factor 4 2.4984
SCN1B sodium channel, voltage gated, type I beta subunit 2.49381
DCAF1 DDB1 and CUL4 associated factor 1 2.49197
XYLT2 xylosyltransferase II 2.48649
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.48532
NKX2-8 NK2 homeobox 8 2.48219
F13B coagulation factor XIII, B polypeptide 2.47866
LPAR2 lysophosphatidic acid receptor 2 2.47413
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 2.47194
AHCYL1 adenosylhomocysteinase-like 1 2.46634
PRLH prolactin releasing hormone 2.46527
GDF2 growth differentiation factor 2 2.4621
WNT3 wingless-type MMTV integration site family, member 3 2.45929
TNMD tenomodulin 2.45525
RAD54L2 RAD54-like 2 (S. cerevisiae) 2.4477
GPR31 G protein-coupled receptor 31 2.43879
LOC107985101 uncharacterized LOC107985101 2.43804
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.42348
ALX4 ALX homeobox 4 2.42007
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.41991
TTPA tocopherol (alpha) transfer protein 2.41844
IFI6 interferon, alpha-inducible protein 6 2.41726
FAM76A family with sequence similarity 76, member A 2.41075
LIPE lipase, hormone-sensitive 2.40513
SFTPB surfactant protein B 2.40279
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.40252
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.40055
DNAH17 dynein, axonemal, heavy chain 17 2.39921
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.39911
GFI1B growth factor independent 1B transcription repressor 2.39381
SOX5 SRY (sex determining region Y)-box 5 2.38964
INCENP inner centromere protein antigens 135/155kDa 2.38622
IFI27 interferon, alpha-inducible protein 27 2.38312
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 2.38242
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.38081
PHTF1 putative homeodomain transcription factor 1 2.3782
GPER1 G protein-coupled estrogen receptor 1 2.37144
CFHR3 complement factor H-related 3 2.3638
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.35668
CCDC70 coiled-coil domain containing 70 2.34766
CCDC40 coiled-coil domain containing 40 2.34324
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.33584
MANBA mannosidase, beta A, lysosomal 2.32685
PRPF39 pre-mRNA processing factor 39 2.32541
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.32343
PRM2 protamine 2 2.3193
HSFX2 heat shock transcription factor family, X linked 2 2.31763
SSTR1 somatostatin receptor 1 2.31628
MRLN myoregulin 2.30847
KIF25 kinesin family member 25 2.30679
ZBTB7B zinc finger and BTB domain containing 7B 2.30622
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.30142
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.29979
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.29874
KISS1 KiSS-1 metastasis-suppressor 2.29809
ISG15 ISG15 ubiquitin-like modifier 2.29573
GPN2 GPN-loop GTPase 2 2.29522
GLB1 galactosidase, beta 1 2.28705
FGGY FGGY carbohydrate kinase domain containing 2.27809
UCN urocortin 2.27043
AIRE autoimmune regulator 2.26607
SCAF8 SR-related CTD-associated factor 8 2.26093
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.25789
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.24959
ZNF280D zinc finger protein 280D 2.24749
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.24351
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.2418
CRYL1 crystallin, lambda 1 2.24159
LEP leptin 2.24092
TSSK2 testis-specific serine kinase 2 2.24005
PLIN1 perilipin 1 2.23684
CA5A carbonic anhydrase VA, mitochondrial 2.2354
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.2288
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.22486
GRM4 glutamate receptor, metabotropic 4 2.22392
AMELY amelogenin, Y-linked 2.22186
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.2199
PTCH2 patched 2 2.21709
CFHR2 complement factor H-related 2 2.21584
CCNO cyclin O 2.21535
C8G complement component 8, gamma polypeptide 2.21457
TNP1 transition protein 1 (during histone to protamine replacement) 2.21431
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.20815
ARR3 arrestin 3, retinal (X-arrestin) 2.20479
POM121L2 POM121 transmembrane nucleoporin-like 2 2.20268
AKAP3 A kinase (PRKA) anchor protein 3 2.20056
PAX7 paired box 7 2.19945
PAGE4 P antigen family, member 4 (prostate associated) 2.19894
ARSA arylsulfatase A 2.19278
CAPN10 calpain 10 2.18929
TOP3B topoisomerase (DNA) III beta 2.18652
TSPO2 translocator protein 2 2.18519
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.18447
GMPPA GDP-mannose pyrophosphorylase A 2.18343
NHLH1 nescient helix loop helix 1 2.17892
TMEM101 transmembrane protein 101 2.17735
MMP2 matrix metallopeptidase 2 2.17703
TMEM242 transmembrane protein 242 2.17445
CT55 cancer/testis antigen 55 2.17313
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.17179
DOT1L DOT1-like histone H3K79 methyltransferase 2.16944
PAGR1 PAXIP1 associated glutamate-rich protein 1 2.16393
DGKG diacylglycerol kinase, gamma 90kDa 2.16351
GRB10 growth factor receptor-bound protein 10 2.16206
AMBP alpha-1-microglobulin/bikunin precursor 2.15757
SHH sonic hedgehog 2.15661
FBXO24 F-box protein 24 2.15523
PRKCE protein kinase C, epsilon 2.1552
HOXA6 homeobox A6 2.15406
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.1491
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.14699
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 2.14449
GPRC5C G protein-coupled receptor, class C, group 5, member C 2.14325
GOLGA6B golgin A6 family, member B 2.14129
HOOK2 hook microtubule-tethering protein 2 2.1411
TDP1 tyrosyl-DNA phosphodiesterase 1 2.14093
CIDEC cell death-inducing DFFA-like effector c 2.13996
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.13436
FBXO31 F-box protein 31 2.13396
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.13055
CCDC82 coiled-coil domain containing 82 2.12956
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.12869
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.12862
CDON cell adhesion associated, oncogene regulated 2.12733
DNAAF8 dynein axonemal assembly factor 8 2.12168
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.1203
COL7A1 collagen, type VII, alpha 1 2.11871
SETDB1 SET domain, bifurcated 1 2.11811
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 2.11402
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.1131
IRGC immunity-related GTPase family, cinema 2.11051
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.10807
CCNF cyclin F 2.10515
SMG6 SMG6 nonsense mediated mRNA decay factor 2.1046
TEX28 testis expressed 28 2.10346
IL13 interleukin 13 2.10023
ADAM10 ADAM metallopeptidase domain 10 2.09934
ZNF142 zinc finger protein 142 2.09914
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.09744
RGSL1 regulator of G-protein signaling like 1 2.09515
CEPT1 choline/ethanolamine phosphotransferase 1 2.0945
FMOD fibromodulin 2.09345
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.09296
PSKH1 protein serine kinase H1 2.09274
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.09241
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.08953
MRPL30 mitochondrial ribosomal protein L30 2.0853
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.08331
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.082
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.08181
TULP1 tubby like protein 1 2.08023
SPTB spectrin, beta, erythrocytic 2.08013
TMEM260 transmembrane protein 260 2.0801
FGF16 fibroblast growth factor 16 2.07728
DHDDS dehydrodolichyl diphosphate synthase 2.07703
EMC10 ER membrane protein complex subunit 10 2.0735
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.07309
CHIA chitinase, acidic 2.07279
ZFC3H1 zinc finger, C3H1-type containing 2.0727
PPA2 pyrophosphatase (inorganic) 2 2.06773
CIDEA cell death-inducing DFFA-like effector a 2.06656
ETV2 ets variant 2 2.06486
DYNC2I1 dynein 2 intermediate chain 1 2.06135
CABP2 calcium binding protein 2 2.05965
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.05941
CCDC33 coiled-coil domain containing 33 2.05934
VWA7 von Willebrand factor A domain containing 7 2.05873
CAPN11 calpain 11 2.05401
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.05377
ANG angiogenin, ribonuclease, RNase A family, 5 2.05288
NEURL1 neuralized E3 ubiquitin protein ligase 1 2.05288
DGUOK deoxyguanosine kinase 2.05037
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.04961
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.04795
MATN4 matrilin 4 2.04676
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.04614
TUBG1 tubulin, gamma 1 2.04413
APCS amyloid P component, serum 2.04373
LRRC3 leucine rich repeat containing 3 2.04241
JPH2 junctophilin 2 2.04137
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.04093
MASP2 mannan-binding lectin serine peptidase 2 2.0397
WDR46 WD repeat domain 46 2.03942
RAD54L RAD54-like (S. cerevisiae) 2.03662
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 2.03644
CLASP1 cytoplasmic linker associated protein 1 2.03482
PRAMEF12 PRAME family member 12 2.03431
ANGPT4 angiopoietin 4 2.02976
XPO4 exportin 4 2.02828
DBF4B DBF4 zinc finger B 2.02669
DMTF1 cyclin D binding myb-like transcription factor 1 2.02595
MMP19 matrix metallopeptidase 19 2.02514
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 2.02367
SMR3B submaxillary gland androgen regulated protein 3B 2.01913
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.01866
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.01864
NMUR1 neuromedin U receptor 1 2.01537
KRT33B keratin 33B, type I 2.01536
GRM2 glutamate receptor, metabotropic 2 2.01338
RDH8 retinol dehydrogenase 8 (all-trans) 2.01318
LOC122526780 uncharacterized LOC122526780 2.01086
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 2.01063
CNTFR ciliary neurotrophic factor receptor 2.01049
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.00993
PRDM8 PR domain containing 8 2.00987
AMH anti-Mullerian hormone 2.00775
ZBTB32 zinc finger and BTB domain containing 32 2.00659
HDAC11 histone deacetylase 11 2.00519
TNXB tenascin XB 2.00438
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.00398

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -9.03906
NCK1 NCK adaptor protein 1 -7.54169
MAPK13 mitogen-activated protein kinase 13 -5.52524
NUP93 nucleoporin 93kDa -5.32488
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -5.26159
VAT1 vesicle amine transport 1 -5.15258
PUF60 poly-U binding splicing factor 60KDa -5.02587
ZDHHC6 zinc finger, DHHC-type containing 6 -4.97772
MRPS2 mitochondrial ribosomal protein S2 -4.85807
DUSP6 dual specificity phosphatase 6 -4.80543
TRIB3 tribbles pseudokinase 3 -4.73438
NT5DC2 5'-nucleotidase domain containing 2 -4.73344
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.72109
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.69355
LAP3 leucine aminopeptidase 3 -4.68569
GTPBP8 GTP-binding protein 8 (putative) -4.61828
TUBB6 tubulin, beta 6 class V -4.54682
DSG2 desmoglein 2 -4.53012
HAT1 histone acetyltransferase 1 -4.48348
THAP11 THAP domain containing 11 -4.45123
NGRN neugrin, neurite outgrowth associated -4.37669
CHMP4B charged multivesicular body protein 4B -4.13701
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.95189
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.90379
TLR4 toll-like receptor 4 -3.80188
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.6388
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.57494
CLNS1A chloride channel, nucleotide-sensitive, 1A -3.08056
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.90675
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.86014
MTA1 metastasis associated 1 -2.83396
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.79858
CTSD cathepsin D -2.79286
YME1L1 YME1-like 1 ATPase -2.7403
CTNND1 catenin (cadherin-associated protein), delta 1 -2.69037
GNAS GNAS complex locus -2.65463
KRT5 keratin 5, type II -2.57717
SLC2A4RG SLC2A4 regulator -2.49557
PRPF4 pre-mRNA processing factor 4 -2.46667
CCDC6 coiled-coil domain containing 6 -2.43615
S100A14 S100 calcium binding protein A14 -2.43585
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.4235
THEM6 thioesterase superfamily member 6 -2.41231
KRT14 keratin 14, type I -2.41043
SCRIB scribbled planar cell polarity protein -2.35701
SCCPDH saccharopine dehydrogenase (putative) -2.35062
ECSIT ECSIT signalling integrator -2.33428
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.33267
ADI1 acireductone dioxygenase 1 -2.32547
ACAA1 acetyl-CoA acyltransferase 1 -2.30312
CRIP2 cysteine-rich protein 2 -2.2931
PEG10 paternally expressed 10 -2.28805
KRT6B keratin 6B, type II -2.26792
PTS 6-pyruvoyltetrahydropterin synthase -2.26029
HSPA12A heat shock 70kDa protein 12A -2.25572
ITGB1BP1 integrin beta 1 binding protein 1 -2.2511
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -2.25108
GID8 GID complex subunit 8 -2.24682
NANS N-acetylneuraminic acid synthase -2.24215
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.24029
PLAAT4 phospholipase A and acyltransferase 4 -2.23178
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.22092
SARAF store-operated calcium entry-associated regulatory factor -2.2201
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.21644
KRT17 keratin 17, type I -2.20879
UQCRB ubiquinol-cytochrome c reductase binding protein -2.19339
CAMLG calcium modulating ligand -2.18537
GSDMD gasdermin D -2.1789
HSPA4 heat shock 70kDa protein 4 -2.16161
MTCH1 mitochondrial carrier 1 -2.16059
KRT6A keratin 6A, type II -2.14774
OSMR oncostatin M receptor -2.1472
ZMIZ1 zinc finger, MIZ-type containing 1 -2.13249
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.09693
EXOC3 exocyst complex component 3 -2.09447
KRT4 keratin 4, type II -2.08796
MLH1 mutL homolog 1 -2.0734
DOK5 docking protein 5 -2.06507
ABHD10 abhydrolase domain containing 10 -2.06241
HDAC9 histone deacetylase 9 -2.05955
TOMM70 translocase of outer mitochondrial membrane 70 -2.05936
TRIB2 tribbles pseudokinase 2 -2.0582
NEFL neurofilament, light polypeptide -2.05751
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.04978
TMEM45A transmembrane protein 45A -2.0435
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 -2.03909
RFC2 replication factor C (activator 1) 2, 40kDa -2.03513
CRABP2 cellular retinoic acid binding protein 2 -2.03212
PLSCR4 phospholipid scramblase 4 -2.02913
ZNF623 zinc finger protein 623 -2.01192
LAPTM4A lysosomal protein transmembrane 4 alpha -2.00688