| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4'-amino[1,1'-biphenyl]-4-ylamine 19.54 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN014_HEPG2_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.33567 |
| KLHL21 | kelch-like family member 21 | 4.31845 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.11477 |
| RRAGA | Ras-related GTP binding A | 3.82812 |
| NOTCH1 | notch 1 | 3.82474 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.00202 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.80919 |
| SFTPB | surfactant protein B | 2.78186 |
| EPHA3 | EPH receptor A3 | 2.7554 |
| LCN2 | lipocalin 2 | 2.69409 |
| ATP11B | ATPase, class VI, type 11B | 2.66712 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.59283 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.56577 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.5597 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.55782 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.55274 |
| HOXA10 | homeobox A10 | 2.53847 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.4702 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.41048 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.33967 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.317 |
| BAX | BCL2-associated X protein | 2.23566 |
| CHN1 | chimerin 1 | 2.23182 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 2.14393 |
| SYF2 | SYF2 pre-mRNA-splicing factor | 2.04792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -6.92205 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.25346 |
| LDHD | lactate dehydrogenase D | -5.35486 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.67159 |
| CCNB2 | cyclin B2 | -4.3841 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.85677 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.07618 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.07301 |
| THAP11 | THAP domain containing 11 | -3.06754 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.06722 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.0511 |
| CCDC86 | coiled-coil domain containing 86 | -2.99029 |
| COG7 | component of oligomeric golgi complex 7 | -2.98787 |
| PLK1 | polo-like kinase 1 | -2.88474 |
| DSG2 | desmoglein 2 | -2.88225 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.83201 |
| RPIA | ribose 5-phosphate isomerase A | -2.81128 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.78279 |
| NGRN | neugrin, neurite outgrowth associated | -2.62578 |
| EGF | epidermal growth factor | -2.54131 |
| TLCD3A | TLC domain containing 3A | -2.51811 |
| DPH2 | DPH2 homolog (S. cerevisiae) | -2.41309 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.36054 |
| CCNH | cyclin H | -2.34855 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | -2.30881 |
| EMC7 | ER membrane protein complex subunit 7 | -2.30851 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.29715 |
| LEP | leptin | -2.12105 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.07906 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.06698 |
| SOCS4 | suppressor of cytokine signaling 4 | -2.01081 |
