CRCGN014_HEPG2_24H:I04 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.07149
|
|
MYLK
|
myosin light chain kinase
|
4.15284
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.86743
|
|
LAGE3
|
L antigen family, member 3
|
3.75965
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.68834
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.37951
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.3177
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.14025
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.03792
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.95263
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.89323
|
|
STK10
|
serine/threonine kinase 10
|
2.81309
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.61727
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.54025
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.43051
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.32383
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.13693
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.09587
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.09431
|
|
RPA3
|
replication protein A3, 14kDa
|
2.0797
|
|
UBL3
|
ubiquitin-like 3
|
2.0195
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.84447
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.71125
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.57658
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.54076
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.48215
|
|
BLVRA
|
biliverdin reductase A
|
-3.3006
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.22919
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.12089
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.89581
|
|
SCAND1
|
SCAN domain containing 1
|
-2.7151
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.64785
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.44234
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.36
|
|
CD320
|
CD320 molecule
|
-2.276
|
|
LDHD
|
lactate dehydrogenase D
|
-2.20744
|
|
CTSD
|
cathepsin D
|
-2.14063
|
|
TLR4
|
toll-like receptor 4
|
-2.13608
|
