CRCGN014_HEPG2_24H:I08 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:I08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.36968
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.82176
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.54722
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.50988
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.46451
|
|
ZNF589
|
zinc finger protein 589
|
3.45125
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.09624
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.98119
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.97514
|
|
SATB1
|
SATB homeobox 1
|
2.73856
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.71724
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.68142
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.63408
|
|
HDGFL3
|
HDGF like 3
|
2.58918
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.49625
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.29598
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.26384
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.15783
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.03059
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.06375
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.1246
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.74456
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.66674
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.29324
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.16753
|
|
ZNF586
|
zinc finger protein 586
|
-2.84095
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.67613
|
|
TSPAN4
|
tetraspanin 4
|
-2.62278
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.54547
|
|
SNX11
|
sorting nexin 11
|
-2.34112
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.2682
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.17783
|
|
GNAS
|
GNAS complex locus
|
-2.12756
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.06264
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.02856
|
