| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-benzyl 2-butyl phthalate 21.13 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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55 genes differentially expressed following the CRCGN014_HEPG2_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 5.08741 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.07825 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.84982 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.73835 |
| ATP11B | ATPase, class VI, type 11B | 4.07549 |
| MAP7 | microtubule-associated protein 7 | 3.92941 |
| HDGFL3 | HDGF like 3 | 3.74752 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.68974 |
| RRAGA | Ras-related GTP binding A | 3.54667 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.42949 |
| NOSIP | nitric oxide synthase interacting protein | 3.33594 |
| PLSCR3 | phospholipid scramblase 3 | 3.11735 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.96213 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.84316 |
| GATA2 | GATA binding protein 2 | 2.74618 |
| DIPK1A | divergent protein kinase domain 1A | 2.70151 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.623 |
| LCN2 | lipocalin 2 | 2.5557 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.41023 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.40049 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.32329 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.29879 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 2.18284 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.17623 |
| NID2 | nidogen 2 (osteonidogen) | 2.1216 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 2.05037 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.01492 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 2.00883 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.32933 |
| FASTKD5 | FAST kinase domains 5 | -4.995 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.79251 |
| DNM1L | dynamin 1-like | -4.48898 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.43297 |
| TRIB3 | tribbles pseudokinase 3 | -4.34267 |
| CDC20 | cell division cycle 20 | -4.30948 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.29082 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -3.84365 |
| LDHD | lactate dehydrogenase D | -3.31882 |
| CDC25B | cell division cycle 25B | -3.28545 |
| CCNB2 | cyclin B2 | -2.93223 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -2.8947 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.82818 |
| GGNBP2 | gametogenetin binding protein 2 | -2.80125 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.75996 |
| REEP5 | receptor accessory protein 5 | -2.45967 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -2.40635 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.38881 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.30317 |
| RCOR3 | REST corepressor 3 | -2.28225 |
| SLC6A16 | solute carrier family 6, member 16 | -2.2705 |
| ZNF586 | zinc finger protein 586 | -2.16371 |
| NDRG4 | NDRG family member 4 | -2.12956 |
| TXNDC9 | thioredoxin domain containing 9 | -2.12791 |
| EPB42 | erythrocyte membrane protein band 4.2 | -2.11459 |
| DCK | deoxycytidine kinase | -2.02093 |