CRCGN014_HEPG2_24H:I10 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:I10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.85553
|
|
ABHD6
|
abhydrolase domain containing 6
|
5.61541
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.0618
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.04615
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.98947
|
|
CYCS
|
cytochrome c, somatic
|
3.69332
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.6483
|
|
MYLK
|
myosin light chain kinase
|
3.33128
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.31102
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.28745
|
|
UBQLN2
|
ubiquilin 2
|
3.1972
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.9923
|
|
STK10
|
serine/threonine kinase 10
|
2.98117
|
|
LCN2
|
lipocalin 2
|
2.83067
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.81397
|
|
E2F2
|
E2F transcription factor 2
|
2.70259
|
|
MAP7
|
microtubule-associated protein 7
|
2.4677
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
2.27926
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.25559
|
|
EVL
|
Enah/Vasp-like
|
2.14442
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-6.7027
|
|
GNAS
|
GNAS complex locus
|
-4.57983
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.76288
|
|
ZNF586
|
zinc finger protein 586
|
-3.63942
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.26167
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.02365
|
|
SNX11
|
sorting nexin 11
|
-2.9912
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.97556
|
|
CDC20
|
cell division cycle 20
|
-2.90582
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.77882
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.7332
|
|
VAT1
|
vesicle amine transport 1
|
-2.64978
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.62131
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.27608
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.23643
|
|
ZNF721
|
zinc finger protein 721
|
-2.2337
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.21984
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.15047
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.1387
|
|
RBM4B
|
RNA binding motif protein 4B
|
-2.04868
|
