CRCGN014_HEPG2_24H:I12 Gene Set

Dataset	Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	mitoxantrone 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1747 genes differentially expressed following the CRCGN014_HEPG2_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol	Name	Standardized Value
PTPN6	protein tyrosine phosphatase, non-receptor type 6	10.0
BPHL	biphenyl hydrolase-like (serine hydrolase)	10.0
SLC27A3	solute carrier family 27 (fatty acid transporter), member 3	8.3257
SHB	Src homology 2 domain containing adaptor protein B	8.2239
IFNAR1	interferon (alpha, beta and omega) receptor 1	8.09845
TENT4A	terminal nucleotidyltransferase 4A	8.0417
CXCR4	chemokine (C-X-C motif) receptor 4	7.96737
H2BC21	H2B clustered histone 21	7.8594
PTK2B	protein tyrosine kinase 2 beta	7.57932
HEBP1	heme binding protein 1	7.53105
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	7.1862
CDPF1	cysteine-rich, DPF motif domain containing 1	6.996
TSEN2	TSEN2 tRNA splicing endonuclease subunit	6.79925
H2BC12	H2B clustered histone 12	6.7661
FOS	FBJ murine osteosarcoma viral oncogene homolog	6.75655
ATP11B	ATPase, class VI, type 11B	6.691
GHR	growth hormone receptor	6.4031
DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	6.35135
UBQLN2	ubiquilin 2	6.2693
STK10	serine/threonine kinase 10	6.24072
PPP1R13B	protein phosphatase 1, regulatory subunit 13B	6.22955
ARID5B	AT rich interactive domain 5B (MRF1-like)	6.17635
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	6.17555
DPH2	DPH2 homolog (S. cerevisiae)	6.1557
TREM1	triggering receptor expressed on myeloid cells 1	6.1451
CPSF4	cleavage and polyadenylation specific factor 4, 30kDa	6.11615
UBE2L6	ubiquitin-conjugating enzyme E2L 6	6.0777
IL1B	interleukin 1, beta	6.032
BZW2	basic leucine zipper and W2 domains 2	5.9953
MUC1	mucin 1, cell surface associated	5.98713
PRKX	protein kinase, X-linked	5.97643
FAM234B	family with sequence similarity 234 member B	5.9559
CIAO3	cytosolic iron-sulfur assembly component 3	5.86555
MSRA	methionine sulfoxide reductase A	5.81685
SMIM40	small integral membrane protein 40	5.80985
LRPAP1	low density lipoprotein receptor-related protein associated protein 1	5.7423
GPC1	glypican 1	5.70272
TERT	telomerase reverse transcriptase	5.676
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	5.6326
TRAPPC6A	trafficking protein particle complex 6A	5.62855
PRCP	prolylcarboxypeptidase (angiotensinase C)	5.5914
ITFG1	integrin alpha FG-GAP repeat containing 1	5.5794
MAMLD1	mastermind-like domain containing 1	5.56545
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	5.5579
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	5.52693
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	5.52105
ARL4C	ADP-ribosylation factor-like 4C	5.51993
FAIM	Fas apoptotic inhibitory molecule	5.49345
PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	5.4478
ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	5.43465
CAPN1	calpain 1, (mu/I) large subunit	5.43165
SYNE2	spectrin repeat containing, nuclear envelope 2	5.42415
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	5.3896
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	5.3865
SBDS	Shwachman-Bodian-Diamond syndrome	5.3852
RTL8A	retrotransposon Gag like 8A	5.37415
BTK	Bruton agammaglobulinemia tyrosine kinase	5.30395
ZFP36	ZFP36 ring finger protein	5.29745
RAB21	RAB21, member RAS oncogene family	5.24115
DYNLT3	dynein, light chain, Tctex-type 3	5.17155
CHAC1	ChaC glutathione-specific gamma-glutamylcyclotransferase 1	5.16855
MCOLN1	mucolipin 1	5.0233
UPB1	ureidopropionase, beta	5.0055
FAM246A	family with sequence similarity 246 member A	4.95005
SOX2	SRY (sex determining region Y)-box 2	4.94362
MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	4.94245
LYN	LYN proto-oncogene, Src family tyrosine kinase	4.93005
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	4.9203
BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	4.911
TSC22D3	TSC22 domain family, member 3	4.89922
NMU	neuromedin U	4.89905
EDN1	endothelin 1	4.8891
GFOD1	glucose-fructose oxidoreductase domain containing 1	4.86805
SOCS2	suppressor of cytokine signaling 2	4.8612
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	4.83615
FZD1	frizzled class receptor 1	4.82242
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	4.8196
IGFBP3	insulin-like growth factor binding protein 3	4.81348
ACKR3	atypical chemokine receptor 3	4.8043
GAA	glucosidase, alpha; acid	4.80115
BAMBI	BMP and activin membrane-bound inhibitor	4.7716
IFT22	intraflagellar transport 22	4.73905
GRHL2	grainyhead-like 2 (Drosophila)	4.7344
ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	4.7221
NPDC1	neural proliferation, differentiation and control, 1	4.70315
GADD45B	growth arrest and DNA-damage-inducible, beta	4.68973
DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	4.677
S100A4	S100 calcium binding protein A4	4.65415
TSPAN12	tetraspanin 12	4.62
CTSD	cathepsin D	4.61
TCEA2	transcription elongation factor A (SII), 2	4.607
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	4.6054
DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	4.57875
PRR15L	proline rich 15-like	4.5537
CDH22	cadherin 22, type 2	4.54995
IL10RB	interleukin 10 receptor, beta	4.5369
GADD45A	growth arrest and DNA-damage-inducible, alpha	4.5351
HSFX2	heat shock transcription factor family, X linked 2	4.5132
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	4.51295
CYB561	cytochrome b561	4.43785
PTMS	parathymosin	4.433
NUP62	nucleoporin 62kDa	4.41893
HEMK2	HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine	4.4137
AP3B2	adaptor-related protein complex 3, beta 2 subunit	4.38205
CRIP2	cysteine-rich protein 2	4.3704
SUSD4	sushi domain containing 4	4.3551
DNASE1L1	deoxyribonuclease I-like 1	4.3422
FBXL12	F-box and leucine-rich repeat protein 12	4.3202
RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	4.3178
RTN2	reticulon 2	4.30005
S100A14	S100 calcium binding protein A14	4.2981
ACOT13	acyl-CoA thioesterase 13	4.2907
PRRG4	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)	4.2829
KIF26B	kinesin family member 26B	4.2725
PLXNA3	plexin A3	4.25642
BHMT	betaine--homocysteine S-methyltransferase	4.24885
IPO13	importin 13	4.24405
UNC13A	unc-13 homolog A (C. elegans)	4.234
FGFR2	fibroblast growth factor receptor 2	4.19934
CRMP1	collapsin response mediator protein 1	4.19445
KIAA1614	KIAA1614	4.1844
H1-2	H1.2 linker histone, cluster member	4.18395
DHRS7	dehydrogenase/reductase (SDR family) member 7	4.1742
HTRA1	HtrA serine peptidase 1	4.14135
IQGAP1	IQ motif containing GTPase activating protein 1	4.13835
CD83	CD83 molecule	4.12495
TRIM46	tripartite motif containing 46	4.1148
CORO1A	coronin, actin binding protein, 1A	4.10895
BACE2	beta-site APP-cleaving enzyme 2	4.0996
HPCA	hippocalcin	4.09115
DUSP4	dual specificity phosphatase 4	4.07982
DPYS	dihydropyrimidinase	4.07965
RAI14	retinoic acid induced 14	4.0775
RIPK4	receptor-interacting serine-threonine kinase 4	4.07695
POLM	polymerase (DNA directed), mu	4.07615
SV2A	synaptic vesicle glycoprotein 2A	4.07
EMC10	ER membrane protein complex subunit 10	4.0593
ACAD10	acyl-CoA dehydrogenase family, member 10	4.04565
SLC18A3	solute carrier family 18 (vesicular acetylcholine transporter), member 3	4.03495
CREG1	cellular repressor of E1A-stimulated genes 1	4.034
CCDC106	coiled-coil domain containing 106	4.0218
NCF1	neutrophil cytosolic factor 1	4.01482
SCPEP1	serine carboxypeptidase 1	4.0103
NOTCH1	notch 1	3.99385
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	3.98955
TRIM13	tripartite motif containing 13	3.9895
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	3.98365
HOXB3	homeobox B3	3.9742
ADGRF1	adhesion G protein-coupled receptor F1	3.96895
ADRA2B	adrenoceptor alpha 2B	3.955
TAGLN3	transgelin 3	3.9532
ATP6V1B1	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	3.94965
ECH1	enoyl CoA hydratase 1, peroxisomal	3.94405
MMP2	matrix metallopeptidase 2	3.9421
MOCS1	molybdenum cofactor synthesis 1	3.93928
HAO2	hydroxyacid oxidase 2 (long chain)	3.93465
RANBP17	RAN binding protein 17	3.93195
PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	3.9254
GPR45	G protein-coupled receptor 45	3.92115
SLC15A3	solute carrier family 15 (oligopeptide transporter), member 3	3.917
ETNK2	ethanolamine kinase 2	3.91685
TMEM120B	transmembrane protein 120B	3.90265
MYCN	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	3.89773
TNNT1	troponin T type 1 (skeletal, slow)	3.8974
SIRT5	sirtuin 5	3.89237
INSIG1	insulin induced gene 1	3.88558
ZNF467	zinc finger protein 467	3.8804
ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	3.86715
TMEM35B	transmembrane protein 35B	3.86468
CAB39L	calcium binding protein 39-like	3.86275
ADGRG1	adhesion G protein-coupled receptor G1	3.8601
FCHO1	FCH domain only 1	3.843
ANGPTL3	angiopoietin-like 3	3.83625
PDE9A	phosphodiesterase 9A	3.8333
FLT4	fms-related tyrosine kinase 4	3.83055
XPNPEP3	X-prolyl aminopeptidase 3, mitochondrial	3.82975
CD9	CD9 molecule	3.7964
BCAP31	B-cell receptor-associated protein 31	3.79045
HUNK	hormonally up-regulated Neu-associated kinase	3.77125
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled	3.7656
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	3.76135
WRNIP1	Werner helicase interacting protein 1	3.76105
L2HGDH	L-2-hydroxyglutarate dehydrogenase	3.7487
INA	internexin neuronal intermediate filament protein, alpha	3.74705
SLC28A1	solute carrier family 28 (concentrative nucleoside transporter), member 1	3.74635
DCUN1D4	DCN1, defective in cullin neddylation 1, domain containing 4	3.71595
CKMT1A	creatine kinase, mitochondrial 1A	3.7144
ZNF362	zinc finger protein 362	3.7017
TBX5	T-box 5	3.70045
ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9	3.69975
CHN1	chimerin 1	3.6997
VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)	3.69815
TIMP2	TIMP metallopeptidase inhibitor 2	3.69765
RNF44	ring finger protein 44	3.69555
SLC2A11	solute carrier family 2 (facilitated glucose transporter), member 11	3.69225
ECHDC3	enoyl CoA hydratase domain containing 3	3.68965
HADH	hydroxyacyl-CoA dehydrogenase	3.6879
SCRN3	secernin 3	3.6862
SSR4	signal sequence receptor, delta	3.68035
ELAC1	elaC ribonuclease Z 1	3.6776
SLC22A13	solute carrier family 22 (organic anion/urate transporter), member 13	3.67315
F8	coagulation factor VIII, procoagulant component	3.66895
CBR4	carbonyl reductase 4	3.6689
SORCS3	sortilin-related VPS10 domain containing receptor 3	3.66685
VRTN	vertebrae development associated	3.66635
ISYNA1	inositol-3-phosphate synthase 1	3.66235
RALYL	RALY RNA binding protein-like	3.65365
GPR18	G protein-coupled receptor 18	3.653
CD200R1	CD200 receptor 1	3.6518
TMEM212	transmembrane protein 212	3.65125
GDI1	GDP dissociation inhibitor 1	3.65095
INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	3.65065
TRAP1	TNF receptor-associated protein 1	3.64855
LPAR2	lysophosphatidic acid receptor 2	3.64707
LGI2	leucine-rich repeat LGI family, member 2	3.6416
ARMCX1	armadillo repeat containing, X-linked 1	3.62865
H2BC6	H2B clustered histone 6	3.62865
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	3.6248
POLH	polymerase (DNA directed), eta	3.61905
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled	3.6189
KLHL1	kelch-like family member 1	3.61595
CBR3	carbonyl reductase 3	3.61395
EXD3	exonuclease 3'-5' domain containing 3	3.6139
IKZF2	IKAROS family zinc finger 2 (Helios)	3.61035
CNPY4	canopy FGF signaling regulator 4	3.6098
PCDHA9	protocadherin alpha 9	3.60425
GTF3A	general transcription factor IIIA	3.60322
ARMCX4	armadillo repeat containing, X-linked 4	3.59845
DUSP11	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)	3.59715
MYCL	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog	3.59567
GBX2	gastrulation brain homeobox 2	3.59255
JCAD	junctional cadherin 5 associated	3.58475
ARHGAP28	Rho GTPase activating protein 28	3.58092
IMPACT	impact RWD domain protein	3.58075
KRT3	keratin 3, type II	3.5802
SLC27A6	solute carrier family 27 (fatty acid transporter), member 6	3.57965
NR1H2	nuclear receptor subfamily 1, group H, member 2	3.5766
H2BC5	H2B clustered histone 5	3.5721
ARL3	ADP-ribosylation factor-like 3	3.57205
NKX6-1	NK6 homeobox 1	3.5637
MYO15A	myosin XVA	3.56245
KCNIP2	Kv channel interacting protein 2	3.55305
SRD5A1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	3.55202
ZFR2	zinc finger RNA binding protein 2	3.55165
ANGPTL2	angiopoietin-like 2	3.54905
CCDC30	coiled-coil domain containing 30	3.5472
LIN28A	lin-28 homolog A (C. elegans)	3.5461
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	3.54545
GRB7	growth factor receptor-bound protein 7	3.5452
MMP24OS	MMP24 opposite strand	3.5382
NXPH4	neurexophilin 4	3.53505
MANBA	mannosidase, beta A, lysosomal	3.53035
KCNA4	potassium channel, voltage gated shaker related subfamily A, member 4	3.5282
PDE5A	phosphodiesterase 5A, cGMP-specific	3.5268
PROZ	protein Z, vitamin K-dependent plasma glycoprotein	3.5136
ONECUT1	one cut homeobox 1	3.5134
GSTZ1	glutathione S-transferase zeta 1	3.51245
PGAP4	post-GPI attachment to proteins GalNAc transferase 4	3.51225
TBX1	T-box 1	3.50772
ZIC3	Zic family member 3	3.505
LSR	lipolysis stimulated lipoprotein receptor	3.5009
GNL1	guanine nucleotide binding protein-like 1	3.49895
GJA8	gap junction protein, alpha 8, 50kDa	3.4956
NUCB2	nucleobindin 2	3.4949
METTL2A	methyltransferase like 2A	3.49465
KCNJ5	potassium channel, inwardly rectifying subfamily J, member 5	3.49235
NPTX2	neuronal pentraxin II	3.4908
COXFA4L2	cytochrome c oxidase hypoxia associated subunit FA4L2	3.48915
STIMATE	STIM activating enhancer	3.48665
ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	3.48505
COLEC10	collectin sub-family member 10 (C-type lectin)	3.4816
KREMEN2	kringle containing transmembrane protein 2	3.4763
CETN3	centrin, EF-hand protein, 3	3.46815
IFT38	intraflagellar transport 38	3.4605
APCS	amyloid P component, serum	3.45645
KCNS3	potassium voltage-gated channel, modifier subfamily S, member 3	3.45355
ANO2	anoctamin 2, calcium activated chloride channel	3.4525
TGFB3	transforming growth factor, beta 3	3.45025
SDK2	sidekick cell adhesion molecule 2	3.4492
RNF2	ring finger protein 2	3.4479
PHF13	PHD finger protein 13	3.445
CAV2	caveolin 2	3.43853
HAGH	hydroxyacylglutathione hydrolase	3.4358
CLCN1	chloride channel, voltage-sensitive 1	3.43145
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	3.41655
CRELD2	cysteine-rich with EGF-like domains 2	3.41355
CCRL2	chemokine (C-C motif) receptor-like 2	3.40975
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	3.40135
EFNB3	ephrin-B3	3.39983
NVL	nuclear VCP-like	3.3976
OXCT1	3-oxoacid CoA transferase 1	3.39645
NKAIN1	Na+/K+ transporting ATPase interacting 1	3.39455
SOX3	SRY (sex determining region Y)-box 3	3.3891
CALCR	calcitonin receptor	3.3875
ECM1	extracellular matrix protein 1	3.38655
GUK1	guanylate kinase 1	3.38655
TSPAN3	tetraspanin 3	3.38015
CCL2	chemokine (C-C motif) ligand 2	3.38005
TMEM40	transmembrane protein 40	3.37675
RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	3.37165
MAGT1	magnesium transporter 1	3.3707
HILPDA	hypoxia inducible lipid droplet-associated	3.3651
SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	3.36485
RNF5	ring finger protein 5, E3 ubiquitin protein ligase	3.36285
KCNA10	potassium channel, voltage gated shaker related subfamily A, member 10	3.36145
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	3.3593
SLC16A2	solute carrier family 16, member 2 (thyroid hormone transporter)	3.35835
LPAR3	lysophosphatidic acid receptor 3	3.35755
LOXL1	lysyl oxidase-like 1	3.3548
H2BC9	H2B clustered histone 9	3.3541
PEDS1	plasmanylethanolamine desaturase 1	3.354
HLX	H2.0-like homeobox	3.34895
PILRA	paired immunoglobin-like type 2 receptor alpha	3.34823
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	3.34675
APOE	apolipoprotein E	3.3455
SLC17A5	solute carrier family 17 (acidic sugar transporter), member 5	3.342
DUSP28	dual specificity phosphatase 28	3.3413
SCN4A	sodium channel, voltage gated, type IV alpha subunit	3.34025
WNT8B	wingless-type MMTV integration site family, member 8B	3.33865
NSDHL	NAD(P) dependent steroid dehydrogenase-like	3.3382
C5AR2	complement component 5a receptor 2	3.3337
VSX1	visual system homeobox 1	3.3335
KL	klotho	3.33345
PDE1B	phosphodiesterase 1B, calmodulin-dependent	3.3324
SPINT1	serine peptidase inhibitor, Kunitz type 1	3.32975
HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	3.32435
CCDC28B	coiled-coil domain containing 28B	3.32345
CYSLTR1	cysteinyl leukotriene receptor 1	3.32285
CPLX3	complexin 3	3.31825
NIPSNAP3B	nipsnap homolog 3B (C. elegans)	3.31645
H2BC15	H2B clustered histone 15	3.3158
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	3.3111
C8A	complement component 8, alpha polypeptide	3.30735
CTSO	cathepsin O	3.29915
TIMM50	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	3.2988
GFUS	GDP-L-fucose synthase	3.29375
PIGF	phosphatidylinositol glycan anchor biosynthesis, class F	3.2924
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	3.2898
TAS2R10	taste receptor, type 2, member 10	3.2841
RNF13	ring finger protein 13	3.28402
ZNF623	zinc finger protein 623	3.28365
ATF6	activating transcription factor 6	3.28157
MPHOSPH8	M-phase phosphoprotein 8	3.27915
NTF3	neurotrophin 3	3.27545
FGF5	fibroblast growth factor 5	3.27453
TBXA2R	thromboxane A2 receptor	3.27227
PCYOX1	prenylcysteine oxidase 1	3.2704
ETV7	ets variant 7	3.2686
STEEP1	STING1 ER exit protein 1	3.26775
SPATA7	spermatogenesis associated 7	3.26705
SYP	synaptophysin	3.2656
MXI1	MAX interactor 1, dimerization protein	3.2613
SLC6A16	solute carrier family 6, member 16	3.2562
NALF2	NALCN channel auxiliary factor 2	3.2545
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9	3.252
TLR3	toll-like receptor 3	3.2509
APOC1	apolipoprotein C-I	3.24977
ZKSCAN4	zinc finger with KRAB and SCAN domains 4	3.24975
RAB6B	RAB6B, member RAS oncogene family	3.24853
SACK1E	scaffolding CK1 anchoring protein E	3.24778
XRCC1	X-ray repair complementing defective repair in Chinese hamster cells 1	3.2467
RHBDF2	rhomboid 5 homolog 2 (Drosophila)	3.24575
PLCH2	phospholipase C, eta 2	3.2428
CRABP1	cellular retinoic acid binding protein 1	3.2423
EHHADH	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	3.24205
UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	3.2406
NMRK1	nicotinamide riboside kinase 1	3.23925
SYNPO	synaptopodin	3.239
PRKACG	protein kinase, cAMP-dependent, catalytic, gamma	3.23825
DUOX1	dual oxidase 1	3.22987
NUCB1	nucleobindin 1	3.22645
RNLS	renalase, FAD-dependent amine oxidase	3.2248
CLDN14	claudin 14	3.22345
HEG1	heart development protein with EGF-like domains 1	3.22333
FLT1	fms-related tyrosine kinase 1	3.2229
ESM1	endothelial cell-specific molecule 1	3.22235
CASP2	caspase 2, apoptosis-related cysteine peptidase	3.2222
FSCN2	fascin actin-bundling protein 2, retinal	3.2206
G6PC2	glucose-6-phosphatase, catalytic, 2	3.21695
BIRC7	baculoviral IAP repeat containing 7	3.21615
TAS2R4	taste receptor, type 2, member 4	3.21485
PLPBP	pyridoxal phosphate binding protein	3.2143
RGS1	regulator of G-protein signaling 1	3.2134
SLC16A8	solute carrier family 16 (monocarboxylate transporter), member 8	3.2118
RNF122	ring finger protein 122	3.20985
SLC6A8	solute carrier family 6 (neurotransmitter transporter), member 8	3.20939
IFT54	intraflagellar transport 54	3.20865
PGK1	phosphoglycerate kinase 1	3.20693
CBLN1	cerebellin 1 precursor	3.2062
APOBR	apolipoprotein B receptor	3.2036
MYOZ3	myozenin 3	3.2008
WDR91	WD repeat domain 91	3.19875
H2BC3	H2B clustered histone 3	3.19815
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	3.19595
MGST3	microsomal glutathione S-transferase 3	3.1932
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	3.1926
HDHD5	haloacid dehalogenase like hydrolase domain containing 5	3.18945
ICAM5	intercellular adhesion molecule 5, telencephalin	3.18825
ASIC1	acid sensing (proton gated) ion channel 1	3.18375
GPR85	G protein-coupled receptor 85	3.18335
ERLIN2	ER lipid raft associated 2	3.18325
FGF23	fibroblast growth factor 23	3.1822
NSG2	neuronal vesicle trafficking associated 2	3.18185
CYP2W1	cytochrome P450, family 2, subfamily W, polypeptide 1	3.1814
LRRK1	leucine-rich repeat kinase 1	3.1789
INSRR	insulin receptor-related receptor	3.17855
KIFBP	kinesin family binding protein	3.1784
PLAUR	plasminogen activator, urokinase receptor	3.1769
CHRNG	cholinergic receptor, nicotinic, gamma (muscle)	3.17235
POLR1B	polymerase (RNA) I polypeptide B, 128kDa	3.17
HSPB1	heat shock 27kDa protein 1	3.16945
SLC34A1	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	3.16888
SLITRK2	SLIT and NTRK-like family, member 2	3.16695
PCDHA2	protocadherin alpha 2	3.165
ODAD2	outer dynein arm docking complex subunit 2	3.16495
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	3.1634
KCNJ14	potassium channel, inwardly rectifying subfamily J, member 14	3.16335
PCCB	propionyl CoA carboxylase, beta polypeptide	3.16005
SPAG8	sperm associated antigen 8	3.15922
EFR3B	EFR3 homolog B (S. cerevisiae)	3.15635
SH3BGRL	SH3 domain binding glutamate-rich protein like	3.15523
THSD4	thrombospondin, type I, domain containing 4	3.15455
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	3.152
JAG2	jagged 2	3.14948
CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4	3.1478
MTMR1	myotubularin related protein 1	3.14531
TAS2R7	taste receptor, type 2, member 7	3.14345
IFT88	intraflagellar transport 88	3.14095
MSI1	musashi RNA-binding protein 1	3.1403
CAPN11	calpain 11	3.14025
ZNF395	zinc finger protein 395	3.13962
TOMM34	translocase of outer mitochondrial membrane 34	3.1386
CALM3	calmodulin 3 (phosphorylase kinase, delta)	3.13697
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	3.13578
LRAT	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	3.1336
LGALS12	lectin, galactoside-binding, soluble, 12	3.13225
TESMIN	testis expressed metallothionein like protein	3.1319
B3GALT4	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4	3.13188
SEPTIN5	septin 5	3.12843
MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1	3.1283
TBC1D8B	TBC1 domain family, member 8B (with GRAM domain)	3.1276
RGS16	regulator of G-protein signaling 16	3.12575
DKK3	dickkopf WNT signaling pathway inhibitor 3	3.12127
POU6F2	POU class 6 homeobox 2	3.11945
ADAM9	ADAM metallopeptidase domain 9	3.11855
SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	3.11693
GPR153	G protein-coupled receptor 153	3.11545
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	3.11505
ARHGAP8	Rho GTPase activating protein 8	3.11298
TBX4	T-box 4	3.1114
FIS1	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	3.11085
NTSR1	neurotensin receptor 1 (high affinity)	3.10625
CETN2	centrin, EF-hand protein, 2	3.10425
RPA3	replication protein A3, 14kDa	3.10375
PRSS23	protease, serine, 23	3.10295
ARMCX2	armadillo repeat containing, X-linked 2	3.10275
SAMD14	sterile alpha motif domain containing 14	3.1018
TRHR	thyrotropin-releasing hormone receptor	3.1004
LAGE3	L antigen family, member 3	3.09605
SPTBN2	spectrin, beta, non-erythrocytic 2	3.0955
MC5R	melanocortin 5 receptor	3.09495
STARD8	StAR-related lipid transfer (START) domain containing 8	3.0938
NPHS1	nephrosis 1, congenital, Finnish type (nephrin)	3.09245
HSF2BP	heat shock transcription factor 2 binding protein	3.09245
CUBN	cubilin (intrinsic factor-cobalamin receptor)	3.092
LDOC1	leucine zipper, down-regulated in cancer 1	3.09135
MKRN3	makorin ring finger protein 3	3.0908
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	3.09063
TRIB2	tribbles pseudokinase 2	3.08822
RAB13	RAB13, member RAS oncogene family	3.0875
GJA4	gap junction protein, alpha 4, 37kDa	3.0873
GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	3.08615
RHBDL1	rhomboid, veinlet-like 1 (Drosophila)	3.08505
FABP6	fatty acid binding protein 6, ileal	3.08405
GJB5	gap junction protein, beta 5, 31.1kDa	3.08335
PTCRA	pre T-cell antigen receptor alpha	3.08275
TASL	TLR adaptor interacting with endolysosomal SLC15A4	3.0788
CD81	CD81 molecule	3.07615
FKBP4	FK506 binding protein 4, 59kDa	3.07552
MRAS	muscle RAS oncogene homolog	3.07505
IMPG2	interphotoreceptor matrix proteoglycan 2	3.0725
DGKA	diacylglycerol kinase, alpha 80kDa	3.0717
GPR87	G protein-coupled receptor 87	3.07165
DDX25	DEAD (Asp-Glu-Ala-Asp) box helicase 25	3.07095
RAMP2	receptor (G protein-coupled) activity modifying protein 2	3.07085
CXXC4	CXXC finger protein 4	3.0691
H1-5	H1.5 linker histone, cluster member	3.06885
YIPF6	Yip1 domain family, member 6	3.06636
S1PR2	sphingosine-1-phosphate receptor 2	3.06605
KCNJ2	potassium channel, inwardly rectifying subfamily J, member 2	3.063
AMELY	amelogenin, Y-linked	3.0614
AP3M2	adaptor-related protein complex 3, mu 2 subunit	3.0611
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	3.05625
DCC	DCC netrin 1 receptor	3.0562
CRTAP	cartilage associated protein	3.055
DCAKD	dephospho-CoA kinase domain containing	3.05408
VEZT	vezatin, adherens junctions transmembrane protein	3.05215
CA7	carbonic anhydrase VII	3.04875
DBF4B	DBF4 zinc finger B	3.0463
PCDHA3	protocadherin alpha 3	3.04383
ADAMTSL2	ADAMTS-like 2	3.04335
NPR1	natriuretic peptide receptor 1	3.04323
CYP2A13	cytochrome P450, family 2, subfamily A, polypeptide 13	3.04295
NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	3.04205
EFNA3	ephrin-A3	3.04095
DGKB	diacylglycerol kinase, beta 90kDa	3.0408
CTBP2	C-terminal binding protein 2	3.0388
SECTM1	secreted and transmembrane 1	3.0365
USP53	ubiquitin specific peptidase 53	3.0349
SYNDIG1	synapse differentiation inducing 1	3.034
H2AJ	H2A.J histone	3.0326
PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	3.0322
PRAMEF10	PRAME family member 10	3.03185
PLAAT2	phospholipase A and acyltransferase 2	3.0301
OR3A3	olfactory receptor, family 3, subfamily A, member 3	3.0291
NHLH2	nescient helix loop helix 2	3.0282
DPYSL3	dihydropyrimidinase-like 3	3.0279
CAMKV	CaM kinase-like vesicle-associated	3.02595
RRAGB	Ras-related GTP binding B	3.02385
PRSS12	protease, serine, 12 (neurotrypsin, motopsin)	3.0234
SPI1	Spi-1 proto-oncogene	3.0209
ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	3.02045
HOXC4	homeobox C4	3.0203
TUSC3	tumor suppressor candidate 3	3.01617
TMEM19	transmembrane protein 19	3.0147
CA14	carbonic anhydrase XIV	3.01205
RND1	Rho family GTPase 1	3.009
TBX6	T-box 6	3.00817
VIM	vimentin	3.00595
NHLH1	nescient helix loop helix 1	3.00535
YPEL5	yippee-like 5 (Drosophila)	3.005
FGF18	fibroblast growth factor 18	3.00427
CTNND1	catenin (cadherin-associated protein), delta 1	3.00178
ACKR5	atypical chemokine receptor 5	3.00125
ARHGAP4	Rho GTPase activating protein 4	3.0008
HPSE	heparanase	2.99825
ERBB4	erb-b2 receptor tyrosine kinase 4	2.99608
ARC	activity-regulated cytoskeleton-associated protein	2.99385
PAX3	paired box 3	2.99283
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	2.9923
SDC1	syndecan 1	2.99178
TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	2.9917
CD52	CD52 molecule	2.99117
CACNG4	calcium channel, voltage-dependent, gamma subunit 4	2.98973
MTFR1	mitochondrial fission regulator 1	2.98907
RIN1	Ras and Rab interactor 1	2.9888
NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	2.98625
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	2.986
P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	2.984
KIR2DL5A	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A	2.9839
KRT86	keratin 86, type II	2.98235
BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)	2.97945
ACSM2A	acyl-CoA synthetase medium-chain family member 2A	2.97405
TDRD12	tudor domain containing 12	2.97195
AKR1A1	aldo-keto reductase family 1, member A1 (aldehyde reductase)	2.9707
GRN	granulin	2.96945
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	2.96945
RGS20	regulator of G-protein signaling 20	2.96925
DNM1	dynamin 1	2.96885
CD300A	CD300a molecule	2.96508
EYA1	EYA transcriptional coactivator and phosphatase 1	2.96475
FAM204A	family with sequence similarity 204, member A	2.9645
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	2.96355
CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	2.9598
BRSK2	BR serine/threonine kinase 2	2.95755
TM7SF3	transmembrane 7 superfamily member 3	2.9571
TSPAN31	tetraspanin 31	2.95685
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	2.95657
NME5	NME/NM23 family member 5	2.95605
SULF1	sulfatase 1	2.95573
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	2.95345
BLNK	B-cell linker	2.95225
TEX13A	testis expressed 13A	2.9516
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	2.94975
NT5DC2	5'-nucleotidase domain containing 2	2.94915
VAMP7	vesicle-associated membrane protein 7	2.94905
KIF17	kinesin family member 17	2.9481
EPS8L1	EPS8-like 1	2.94784
GTF2IRD2B	GTF2I repeat domain containing 2B	2.9475
N4BP3	NEDD4 binding protein 3	2.9466
ANGPTL4	angiopoietin-like 4	2.9448
BRINP1	bone morphogenetic protein/retinoic acid inducible neural-specific 1	2.944
BMP5	bone morphogenetic protein 5	2.9427
ULBP1	UL16 binding protein 1	2.9427
DSE	dermatan sulfate epimerase	2.9418
PHAF1	phagosome assembly factor 1	2.94015
SPIDR	scaffolding protein involved in DNA repair	2.93875
CSPG4	chondroitin sulfate proteoglycan 4	2.93788
GEMIN7	gem (nuclear organelle) associated protein 7	2.9369
C1GALT1C1	C1GALT1-specific chaperone 1	2.9348
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	2.93382
HAT1	histone acetyltransferase 1	2.93305
NCKIPSD	NCK interacting protein with SH3 domain	2.9322
WNT16	wingless-type MMTV integration site family, member 16	2.9285
STC1	stanniocalcin 1	2.92685
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	2.92675
ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)	2.9266
DLK2	delta-like 2 homolog (Drosophila)	2.9265
TAPBP	TAP binding protein (tapasin)	2.92598
ADAM2	ADAM metallopeptidase domain 2	2.92555
RSU1	Ras suppressor protein 1	2.92455
TDRD3	tudor domain containing 3	2.92448
GPR6	G protein-coupled receptor 6	2.9239
SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	2.9237
NABP2	nucleic acid binding protein 2	2.923
PECAM1	platelet/endothelial cell adhesion molecule 1	2.9219
BFSP1	beaded filament structural protein 1, filensin	2.92155
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	2.91978
RNF170	ring finger protein 170	2.9189
WDR46	WD repeat domain 46	2.9183
MILR1	mast cell immunoglobulin-like receptor 1	2.91815
TMEM254	transmembrane protein 254	2.91755
PLPPR4	phospholipid phosphatase related 4	2.9139
PAX1	paired box 1	2.91325
KCNJ1	potassium channel, inwardly rectifying subfamily J, member 1	2.91165
A4GALT	alpha 1,4-galactosyltransferase	2.90975
CD5L	CD5 molecule-like	2.9067
ALK	anaplastic lymphoma receptor tyrosine kinase	2.90628
STMN3	stathmin-like 3	2.9058
PTPRC	protein tyrosine phosphatase, receptor type, C	2.90535
SPEG	SPEG complex locus	2.9042
CEMP1	cementum protein 1	2.9032
CIRSR	corepressor of RBPJ and splicing regulator	2.89855
NIPAL3	NIPA-like domain containing 3	2.89648
AVPR2	arginine vasopressin receptor 2	2.8951
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	2.89468
MMP11	matrix metallopeptidase 11	2.89428
PCLO	piccolo presynaptic cytomatrix protein	2.89428
AFM	afamin	2.8942
FRMD4A	FERM domain containing 4A	2.8941
UST	uronyl-2-sulfotransferase	2.89357
FOXH1	forkhead box H1	2.89135
HCN4	hyperpolarization activated cyclic nucleotide gated potassium channel 4	2.8891
RGCC	regulator of cell cycle	2.8881
DCAF16	DDB1 and CUL4 associated factor 16	2.88785
ZNF500	zinc finger protein 500	2.88778
SOX18	SRY (sex determining region Y)-box 18	2.88775
OR7C1	olfactory receptor, family 7, subfamily C, member 1	2.88745
IPP	intracisternal A particle-promoted polypeptide	2.8861
CRYBG2	crystallin beta-gamma domain containing 2	2.88517
BDKRB1	bradykinin receptor B1	2.88485
MAPK12	mitogen-activated protein kinase 12	2.88345
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	2.88305
NFU1	NFU1 iron-sulfur cluster scaffold	2.8824
HIGD1B	HIG1 hypoxia inducible domain family, member 1B	2.8813
CCDC181	coiled-coil domain containing 181	2.88085
PHKB	phosphorylase kinase, beta	2.88037
SRI	sorcin	2.8801
ZMYM2	zinc finger, MYM-type 2	2.8792
TOP6BL	TOP6B like initiator of meiotic double strand breaks	2.8778
RIDA	reactive intermediate imine deaminase A homolog	2.87715
OR2C1	olfactory receptor, family 2, subfamily C, member 1	2.877
HSPB3	heat shock 27kDa protein 3	2.87665
SLC17A4	solute carrier family 17, member 4	2.87595
MOGAT3	monoacylglycerol O-acyltransferase 3	2.87455
EGLN3	egl-9 family hypoxia-inducible factor 3	2.8731
SRD5A3	steroid 5 alpha-reductase 3	2.8729
CHPF	chondroitin polymerizing factor	2.87035
GPR32	G protein-coupled receptor 32	2.8655
SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	2.8646
CREBL2	cAMP responsive element binding protein-like 2	2.86165
FBXO40	F-box protein 40	2.86145
CZIB	CXXC motif containing zinc binding protein	2.85835
NOX5	NADPH oxidase, EF-hand calcium binding domain 5	2.8571
ZBED2	zinc finger, BED-type containing 2	2.8557
ARMCX5-GPRASP2	ARMCX5-GPRASP2 readthrough	2.8549
ANGPT2	angiopoietin 2	2.85432
ASCL1	achaete-scute family bHLH transcription factor 1	2.8538
CATSPERH	catsper channel auxiliary subunit eta	2.852
MN1	meningioma (disrupted in balanced translocation) 1	2.8516
ZNF74	zinc finger protein 74	2.85
SLC6A12	solute carrier family 6 (neurotransmitter transporter), member 12	2.84975
RNF103-CHMP3	RNF103-CHMP3 readthrough	2.8488
MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma	2.8482
PIGB	phosphatidylinositol glycan anchor biosynthesis, class B	2.8478
CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2	2.84778
HOXB5	homeobox B5	2.84648
SHCBP1L	SHC SH2-domain binding protein 1-like	2.8453
ADAM18	ADAM metallopeptidase domain 18	2.84515
GSTT4	glutathione S-transferase theta 4	2.84445
GRM5	glutamate receptor, metabotropic 5	2.84387
SQOR	sulfide quinone oxidoreductase	2.84105
DENND1A	DENN/MADD domain containing 1A	2.8409
TESK1	testis-specific kinase 1	2.83915
PTH1R	parathyroid hormone 1 receptor	2.83885
CHRNA10	cholinergic receptor, nicotinic, alpha 10 (neuronal)	2.83685
RBM41	RNA binding motif protein 41	2.83585
C3AR1	complement component 3a receptor 1	2.8336
ZC4H2	zinc finger, C4H2 domain containing	2.8324
PCDHGA11	protocadherin gamma subfamily A, 11	2.83145
TBC1D22B	TBC1 domain family, member 22B	2.8311
H2BC4	H2B clustered histone 4	2.83092
ZIC4	Zic family member 4	2.83065
FOXL1	forkhead box L1	2.8305
RHCE	Rh blood group, CcEe antigens	2.8305
WDR5B	WD repeat domain 5B	2.83035
SUGCT	succinyl-CoA:glutarate-CoA transferase	2.8301
ADGRD2	adhesion G protein-coupled receptor D2	2.8293
RDH16	retinol dehydrogenase 16 (all-trans)	2.8281
ANKRD6	ankyrin repeat domain 6	2.82798
KCNJ8	potassium channel, inwardly rectifying subfamily J, member 8	2.8241
TMCO1	transmembrane and coiled-coil domains 1	2.82257
MBD5	methyl-CpG binding domain protein 5	2.82155
RAB25	RAB25, member RAS oncogene family	2.81895
UMOD	uromodulin	2.8184
KLF11	Kruppel-like factor 11	2.81665
NANOS1	nanos homolog 1 (Drosophila)	2.81457
PSPN	persephin	2.8143
PCDHGA8	protocadherin gamma subfamily A, 8	2.81425
HES2	hes family bHLH transcription factor 2	2.81348
RPGRIP1L	RPGRIP1-like	2.81255
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2	2.81157
KCNF1	potassium channel, voltage gated modifier subfamily F, member 1	2.81145
GSTA1	glutathione S-transferase alpha 1	2.811
SLC9A3	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	2.8103
GEMIN8	gem (nuclear organelle) associated protein 8	2.8096
KCNA1	potassium channel, voltage gated shaker related subfamily A, member 1	2.8081
MEIS2	Meis homeobox 2	2.808
P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	2.8077
KCNB2	potassium channel, voltage gated Shab related subfamily B, member 2	2.80465
AP3S1	adaptor-related protein complex 3, sigma 1 subunit	2.8039
CARD14	caspase recruitment domain family, member 14	2.8024
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	2.80188
FGFR4	fibroblast growth factor receptor 4	2.8009
TMEM158	transmembrane protein 158 (gene/pseudogene)	2.7984
SH2B2	SH2B adaptor protein 2	2.79505
FCN3	ficolin (collagen/fibrinogen domain containing) 3	2.7925
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	2.78835
LAMP3	lysosomal-associated membrane protein 3	2.7875
PTPRF	protein tyrosine phosphatase, receptor type, F	2.78653
GDAP2	ganglioside induced differentiation associated protein 2	2.7863
DCAF4	DDB1 and CUL4 associated factor 4	2.78595
PRRG2	proline rich Gla (G-carboxyglutamic acid) 2	2.7826
MBTD1	mbt domain containing 1	2.7807
SLC30A4	solute carrier family 30 (zinc transporter), member 4	2.77915
CMC4	C-x(9)-C motif containing 4	2.77898
CABP2	calcium binding protein 2	2.7776
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	2.77745
APOBEC3G	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G	2.77668
TMEM176A	transmembrane protein 176A	2.77635
RAB31	RAB31, member RAS oncogene family	2.77405
SREK1IP1	SREK1-interacting protein 1	2.77395
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	2.7697
KIAA0319	KIAA0319	2.76925
KCNMB3	potassium channel subfamily M regulatory beta subunit 3	2.7682
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	2.76802
PROP1	PROP paired-like homeobox 1	2.76655
XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	2.7665
CFHR3	complement factor H-related 3	2.76585
PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	2.76345
GABRQ	gamma-aminobutyric acid (GABA) A receptor, theta	2.7631
RIC3	RIC3 acetylcholine receptor chaperone	2.7617
LTB	lymphotoxin beta (TNF superfamily, member 3)	2.7607
ESR2	estrogen receptor 2 (ER beta)	2.75964
C8G	complement component 8, gamma polypeptide	2.7588
DYNC2I1	dynein 2 intermediate chain 1	2.75845
AJAP1	adherens junctions associated protein 1	2.75831
ABCA7	ATP-binding cassette, sub-family A (ABC1), member 7	2.7574
LRRC49	leucine rich repeat containing 49	2.7526
NANOG	Nanog homeobox	2.75045
RGS5	regulator of G-protein signaling 5	2.74972
ZNF155	zinc finger protein 155	2.74865
KRT32	keratin 32, type I	2.7482
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	2.74735
HOXC5	homeobox C5	2.74665
RHOQ	ras homolog family member Q	2.74493
THAP10	THAP domain containing 10	2.74485
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	2.74475
SLC16A4	solute carrier family 16, member 4	2.74315
GRM8	glutamate receptor, metabotropic 8	2.74232
AGER	advanced glycosylation end product-specific receptor	2.74003
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	2.73945
HCK	HCK proto-oncogene, Src family tyrosine kinase	2.73905
ZIM2	zinc finger, imprinted 2	2.7389
H2AC6	H2A clustered histone 6	2.73795
SPIN2A	spindlin family, member 2A	2.7368
FSHR	follicle stimulating hormone receptor	2.73595
TEP1	telomerase-associated protein 1	2.73565
RGS19	regulator of G-protein signaling 19	2.73475
SCG3	secretogranin III	2.73465
LOC124900193	uncharacterized LOC124900193	2.73355
SLC4A5	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	2.7334
CEP41	centrosomal protein 41kDa	2.7333
FAM200C	family with sequence similarity 200 member C	2.72935
CD1D	CD1d molecule	2.72835
HTR3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	2.72825
SPACA1	sperm acrosome associated 1	2.72665
KDM8	lysine (K)-specific demethylase 8	2.7256
ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif, 13	2.7253
RBM8A	RNA binding motif protein 8A	2.72456
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	2.72395
PCDH1	protocadherin 1	2.72345
PHACTR1	phosphatase and actin regulator 1	2.72235
TAAR5	trace amine associated receptor 5	2.7223
ACSM5	acyl-CoA synthetase medium-chain family member 5	2.72188
TCAP	titin-cap	2.72025
IGFBP5	insulin-like growth factor binding protein 5	2.71922
PLG	plasminogen	2.71913
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	2.71895
IL36A	interleukin 36, alpha	2.7187
CAV1	caveolin 1, caveolae protein, 22kDa	2.71802
L1CAM	L1 cell adhesion molecule	2.718
AHSP	alpha hemoglobin stabilizing protein	2.7178
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	2.71667
F11R	F11 receptor	2.71642
SEC14L4	SEC14-like 4 (S. cerevisiae)	2.71615
IVNS1ABP	influenza virus NS1A binding protein	2.71515
MECR	mitochondrial trans-2-enoyl-CoA reductase	2.71395
TEX14	testis expressed 14	2.71335
LINC02854	long intergenic non-protein coding RNA 2854	2.70955
SCN8A	sodium channel, voltage gated, type VIII alpha subunit	2.7089
GNS	glucosamine (N-acetyl)-6-sulfatase	2.70845
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	2.7084
MPC2	mitochondrial pyruvate carrier 2	2.70785
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	2.70775
THNSL1	threonine synthase-like 1 (S. cerevisiae)	2.7051
ATF7	activating transcription factor 7	2.7051
CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	2.705
EYA3	EYA transcriptional coactivator and phosphatase 3	2.705
NECAP2	NECAP endocytosis associated 2	2.70375
GPR27	G protein-coupled receptor 27	2.7035
TRO	trophinin	2.70255
COL19A1	collagen, type XIX, alpha 1	2.70255
IL13RA1	interleukin 13 receptor, alpha 1	2.70226
HABP2	hyaluronan binding protein 2	2.7011
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	2.70075
CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	2.7002
NAGA	N-acetylgalactosaminidase, alpha-	2.6999
BICDL1	BICD family like cargo adaptor 1	2.6981
CDKL3	cyclin-dependent kinase-like 3	2.6975
PTCD2	pentatricopeptide repeat domain 2	2.6954
BEX4	brain expressed, X-linked 4	2.69465
LGMN	legumain	2.6935
PDGFB	platelet-derived growth factor beta polypeptide	2.69262
MAP6D1	MAP6 domain containing 1	2.6926
NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	2.69245
HRH2	histamine receptor H2	2.6883
ADRA2C	adrenoceptor alpha 2C	2.68825
SNX7	sorting nexin 7	2.68815
TNP1	transition protein 1 (during histone to protamine replacement)	2.6867
PRDM9	PR domain containing 9	2.68545
KCNAB1	potassium channel, voltage gated subfamily A regulatory beta subunit 1	2.68541
RND3	Rho family GTPase 3	2.68535
PAFAH2	platelet-activating factor acetylhydrolase 2, 40kDa	2.68535
GTF2A1	general transcription factor IIA, 1, 19/37kDa	2.6826
COG7	component of oligomeric golgi complex 7	2.6821
THEMIS2	thymocyte selection associated family member 2	2.68208
GCHFR	GTP cyclohydrolase I feedback regulator	2.67965
PAX2	paired box 2	2.67965
IQSEC2	IQ motif and Sec7 domain 2	2.67935
FMO4	flavin containing monooxygenase 4	2.67928
TAF13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	2.6789
PTP4A3	protein tyrosine phosphatase type IVA, member 3	2.67885
ZNF3	zinc finger protein 3	2.67867
KIAA0408	KIAA0408	2.67775
GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	2.67742
TSKS	testis-specific serine kinase substrate	2.67725
GPR50	G protein-coupled receptor 50	2.6759
INPP5B	inositol polyphosphate-5-phosphatase, 75kDa	2.6759
LRIT1	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	2.6752
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	2.67473
ANKRD46	ankyrin repeat domain 46	2.6734
SNAI1	snail family zinc finger 1	2.67295
ITGB7	integrin, beta 7	2.67205
MARCHF2	membrane associated ring-CH-type finger 2	2.67175
NEU2	sialidase 2 (cytosolic sialidase)	2.6714
PFKM	phosphofructokinase, muscle	2.6711
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	2.6707
WNT6	wingless-type MMTV integration site family, member 6	2.6699
H1-4	H1.4 linker histone, cluster member	2.6688
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2	2.6684
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	2.6679
FKBPL	FK506 binding protein like	2.6678
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	2.66625
NNAT	neuronatin	2.6655
MMP24	matrix metallopeptidase 24 (membrane-inserted)	2.66432
TRIM11	tripartite motif containing 11	2.6641
KIRREL1	kirre like nephrin family adhesion molecule 1	2.66285
CDHR1	cadherin-related family member 1	2.66215
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	2.6609
EML2	echinoderm microtubule associated protein like 2	2.66013
WNT7B	wingless-type MMTV integration site family, member 7B	2.6598
HOXD9	homeobox D9	2.65905
GM2A	GM2 ganglioside activator	2.65727
SLC1A7	solute carrier family 1 (glutamate transporter), member 7	2.65683
ADRA1A	adrenoceptor alpha 1A	2.6568
TCF15	transcription factor 15 (basic helix-loop-helix)	2.6557
PVRIG	poliovirus receptor related immunoglobulin domain containing	2.65465
SALL2	spalt-like transcription factor 2	2.65405
TIAM1	T-cell lymphoma invasion and metastasis 1	2.65252
CLBA1	clathrin binding box of aftiphilin containing 1	2.65195
ADAM23	ADAM metallopeptidase domain 23	2.65127
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	2.651
SLC22A14	solute carrier family 22, member 14	2.65065
KRT37	keratin 37, type I	2.6501
GDF2	growth differentiation factor 2	2.6499
CNTFR	ciliary neurotrophic factor receptor	2.64955
FLCN	folliculin	2.64945
TAS2R9	taste receptor, type 2, member 9	2.6493
DALRD3	DALR anticodon binding domain containing 3	2.64882
FABP2	fatty acid binding protein 2, intestinal	2.6487
SYN3	synapsin III	2.64785
OR1D2	olfactory receptor, family 1, subfamily D, member 2	2.6477
GAD1	glutamate decarboxylase 1 (brain, 67kDa)	2.64627
HIF3A	hypoxia inducible factor 3, alpha subunit	2.64568
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	2.64455
DEPP1	DEPP autophagy regulator 1	2.6444
LPXN	leupaxin	2.64365
CHMP5	charged multivesicular body protein 5	2.64317
SIX3	SIX homeobox 3	2.6421
SLC12A3	solute carrier family 12 (sodium/chloride transporter), member 3	2.64153
CTBS	chitobiase, di-N-acetyl-	2.64127
TRPV5	transient receptor potential cation channel, subfamily V, member 5	2.64115
COL1A2	collagen, type I, alpha 2	2.64022
ZKSCAN3	zinc finger with KRAB and SCAN domains 3	2.6393
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter), member 1	2.6392
SCD5	stearoyl-CoA desaturase 5	2.63755
DNAH7	dynein, axonemal, heavy chain 7	2.6372
B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	2.6372
INSM1	insulinoma-associated 1	2.6361
MRPL57	mitochondrial ribosomal protein L57	2.6355
ALG5	ALG5, dolichyl-phosphate beta-glucosyltransferase	2.6354
OR7C2	olfactory receptor, family 7, subfamily C, member 2	2.6341
FAM153A	family with sequence similarity 153, member A	2.63383
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	2.63357
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	2.63268
AQP9	aquaporin 9	2.631
ARB2A	ARB2 cotranscriptional regulator A	2.6306
MYL10	myosin, light chain 10, regulatory	2.63027
PRDM14	PR domain containing 14	2.62835
ERC2	ELKS/RAB6-interacting/CAST family member 2	2.62822
KCNMA1	potassium channel, calcium activated large conductance subfamily M alpha, member 1	2.6273
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	2.6273
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	2.6269
SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8	2.62565
PECR	peroxisomal trans-2-enoyl-CoA reductase	2.6255
PPARG	peroxisome proliferator-activated receptor gamma	2.62545
NUAK2	NUAK family, SNF1-like kinase, 2	2.62525
PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	2.62521
GRIA4	glutamate receptor, ionotropic, AMPA 4	2.6232
ADAM30	ADAM metallopeptidase domain 30	2.6229
TRMT2B	tRNA methyltransferase 2 homolog B (S. cerevisiae)	2.62195
IQCK	IQ motif containing K	2.62118
SEC22A	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	2.62085
PTPRS	protein tyrosine phosphatase, receptor type, S	2.6207
PRSS16	protease, serine, 16 (thymus)	2.62065
INKA2	inka box actin regulator 2	2.62065
H2AC19	H2A clustered histone 19	2.62057
OTUD7B	OTU deubiquitinase 7B	2.61955
STAU2	staufen double-stranded RNA binding protein 2	2.61785
TMBIM4	transmembrane BAX inhibitor motif containing 4	2.6162
DRD1	dopamine receptor D1	2.6158
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	2.61427
GUCY2D	guanylate cyclase 2D, membrane (retina-specific)	2.6139
CETN1	centrin, EF-hand protein, 1	2.6128
IRGC	immunity-related GTPase family, cinema	2.6127
DBT	dihydrolipoamide branched chain transacylase E2	2.61144
KIAA1549L	KIAA1549-like	2.61125
WASHC5	WASH complex subunit 5	2.6108
CRABP2	cellular retinoic acid binding protein 2	2.61045
SPRYD7	SPRY domain containing 7	2.61015
INHBC	inhibin, beta C	2.6086
TYROBP	TYRO protein tyrosine kinase binding protein	2.60605
MAT1A	methionine adenosyltransferase I, alpha	2.6048
KNTC1	kinetochore associated 1	2.60285
RNF128	ring finger protein 128, E3 ubiquitin protein ligase	2.6021
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	2.6016
ALDH3A2	aldehyde dehydrogenase 3 family, member A2	2.60135
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	2.60045
F2RL2	coagulation factor II (thrombin) receptor-like 2	2.5992
TLX1	T-cell leukemia homeobox 1	2.59795
TMCC2	transmembrane and coiled-coil domain family 2	2.5978
POU5F1	POU class 5 homeobox 1	2.59744
EPN3	epsin 3	2.5969
FEZF2	FEZ family zinc finger 2	2.5962
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	2.59485
TCP10L	t-complex 10-like	2.5948
ATG10	autophagy related 10	2.59455
MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	2.59345
DNAAF8	dynein axonemal assembly factor 8	2.5908
GRTP1	growth hormone regulated TBC protein 1	2.59055
TULP3	tubby like protein 3	2.5905
SCARB1	scavenger receptor class B, member 1	2.58842
MYOD1	myogenic differentiation 1	2.58835
C5AR1	complement component 5a receptor 1	2.58595
MSR1	macrophage scavenger receptor 1	2.58581
PCGF1	polycomb group ring finger 1	2.58343
MATN4	matrilin 4	2.58305
FSHB	follicle stimulating hormone, beta polypeptide	2.58205
CCDC144A	coiled-coil domain containing 144A	2.5801
ATG12	autophagy related 12	2.5792
MYL7	myosin, light chain 7, regulatory	2.57785
OPN1MW3	opsin 1, medium wave sensitive 3	2.5775
ETV3	ets variant 3	2.57675
SYT13	synaptotagmin XIII	2.57665
SRPK3	SRSF protein kinase 3	2.5759
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	2.5756
SLC22A8	solute carrier family 22 (organic anion transporter), member 8	2.57525
KIAA0930	KIAA0930	2.57468
SPATA6L	spermatogenesis associated 6-like	2.5741

decreased expression

Symbol	Name	Standardized Value
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	-10.0
MYC	v-myc avian myelocytomatosis viral oncogene homolog	-10.0
PUF60	poly-U binding splicing factor 60KDa	-10.0
TCERG1	transcription elongation regulator 1	-9.94735
ARFIP2	ADP-ribosylation factor interacting protein 2	-9.8961
FASTKD5	FAST kinase domains 5	-9.86685
SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5	-9.86175
CASC3	cancer susceptibility candidate 3	-9.79295
THAP11	THAP domain containing 11	-9.50115
DNM1L	dynamin 1-like	-9.3049
SCAND1	SCAN domain containing 1	-9.2785
ABL1	ABL proto-oncogene 1, non-receptor tyrosine kinase	-9.1162
CDK7	cyclin-dependent kinase 7	-8.9358
TXLNA	taxilin alpha	-8.8062
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	-8.6764
CASP3	caspase 3, apoptosis-related cysteine peptidase	-8.2446
CLTC	clathrin, heavy chain (Hc)	-8.23185
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	-8.20745
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	-8.1613
GDF15	growth differentiation factor 15	-8.0696
PPP2R3C	protein phosphatase 2, regulatory subunit B'', gamma	-7.56745
MRPL12	mitochondrial ribosomal protein L12	-7.52835
SLC35F2	solute carrier family 35, member F2	-7.4526
MAP3K4	mitogen-activated protein kinase kinase kinase 4	-7.3565
ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	-7.31628
PLK1	polo-like kinase 1	-7.28955
PSMG1	proteasome (prosome, macropain) assembly chaperone 1	-7.24175
KEAP1	kelch-like ECH-associated protein 1	-7.20445
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	-7.03
KLHL21	kelch-like family member 21	-6.98175
CLPX	caseinolytic mitochondrial matrix peptidase chaperone subunit	-6.9131
CCDC86	coiled-coil domain containing 86	-6.8834
FHL2	four and a half LIM domains 2	-6.82755
PLEKHJ1	pleckstrin homology domain containing, family J member 1	-6.67915
MELK	maternal embryonic leucine zipper kinase	-6.66725
CCNA2	cyclin A2	-6.58772
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	-6.52665
ZDHHC6	zinc finger, DHHC-type containing 6	-6.48055
ASCC3	activating signal cointegrator 1 complex subunit 3	-6.3309
LBR	lamin B receptor	-6.32845
TOP2A	topoisomerase (DNA) II alpha 170kDa	-6.2506
ZNF586	zinc finger protein 586	-6.05735
ADO	2-aminoethanethiol (cysteamine) dioxygenase	-5.96467
C2CD5	C2 calcium-dependent domain containing 5	-5.917
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	-5.9142
EAPP	E2F-associated phosphoprotein	-5.80015
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	-5.78207
TOMM70	translocase of outer mitochondrial membrane 70	-5.71747
TATDN2	TatD DNase domain containing 2	-5.58625
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	-5.57685
SUZ12	SUZ12 polycomb repressive complex 2 subunit	-5.53442
EED	embryonic ectoderm development	-5.45145
MRPS2	mitochondrial ribosomal protein S2	-5.45055
INTS3	integrator complex subunit 3	-5.4487
USP1	ubiquitin specific peptidase 1	-5.43255
CDC25B	cell division cycle 25B	-5.4064
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	-5.3673
JMJD6	jumonji domain containing 6	-5.32913
RRAGA	Ras-related GTP binding A	-5.3264
PCM1	pericentriolar material 1	-5.29189
GRWD1	glutamate-rich WD repeat containing 1	-5.2818
EDC4	enhancer of mRNA decapping 4	-5.20965
ENOPH1	enolase-phosphatase 1	-5.17935
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	-5.15917
GABPB1	GA binding protein transcription factor, beta subunit 1	-5.14178
RNMT	RNA (guanine-7-) methyltransferase	-5.12713
UBE3C	ubiquitin protein ligase E3C	-5.10495
HSD17B11	hydroxysteroid (17-beta) dehydrogenase 11	-5.0694
GLOD4	glyoxalase domain containing 4	-5.0454
SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	-5.0011
RPS4Y1	ribosomal protein S4, Y-linked 1	-5.0
ZNF518A	zinc finger protein 518A	-4.97965
RBM14-RBM4	RBM14-RBM4 readthrough	-4.95935
AAR2	AAR2 splicing factor homolog (S. cerevisiae)	-4.9365
BLVRA	biliverdin reductase A	-4.91617
NOLC1	nucleolar and coiled-body phosphoprotein 1	-4.90828
IST1	increased sodium tolerance 1 homolog (yeast)	-4.87505
MICALL1	MICAL-like 1	-4.81862
KIF13B	kinesin family member 13B	-4.79425
TMEM11	transmembrane protein 11	-4.7898
AFG3L2	AFG3-like AAA ATPase 2	-4.7459
TRAPPC3	trafficking protein particle complex 3	-4.738
EMC8	ER membrane protein complex subunit 8	-4.7293
RPP38	ribonuclease P/MRP 38kDa subunit	-4.7288
KAT5	K(lysine) acetyltransferase 5	-4.66098
POLE2	polymerase (DNA directed), epsilon 2, accessory subunit	-4.65205
PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	-4.62983
GPATCH8	G patch domain containing 8	-4.625
VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	-4.59845
SCAF8	SR-related CTD-associated factor 8	-4.5954
TRIB1	tribbles pseudokinase 1	-4.586
VPS4A	vacuolar protein sorting 4 homolog A (S. cerevisiae)	-4.51935
LDHD	lactate dehydrogenase D	-4.45635
DHX29	DEAH (Asp-Glu-Ala-His) box polypeptide 29	-4.45435
SKIC2	SKI2 subunit of superkiller complex	-4.452
PCNA	proliferating cell nuclear antigen	-4.42685
SLC2A6	solute carrier family 2 (facilitated glucose transporter), member 6	-4.41315
ZNHIT6	zinc finger, HIT-type containing 6	-4.3378
WDR82	WD repeat domain 82	-4.28785
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	-4.28285
NCK1	NCK adaptor protein 1	-4.27375
DHRS11	dehydrogenase/reductase (SDR family) member 11	-4.2674
KIF14	kinesin family member 14	-4.2529
BLMH	bleomycin hydrolase	-4.2485
PRPF38B	pre-mRNA processing factor 38B	-4.23217
USP22	ubiquitin specific peptidase 22	-4.22215
CD320	CD320 molecule	-4.21045
EEIG1	estrogen-induced osteoclastogenesis regulator 1	-4.20975
MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	-4.18937
DCK	deoxycytidine kinase	-4.1537
AARS1	alanyl-tRNA synthetase 1	-4.1227
HMOX1	heme oxygenase 1	-4.11675
SLC25A13	solute carrier family 25 (aspartate/glutamate carrier), member 13	-4.1012
WTAP	Wilms tumor 1 associated protein	-4.0885
NAP1L4	nucleosome assembly protein 1-like 4	-4.08105
PARP2	poly (ADP-ribose) polymerase 2	-4.05273
ERBB2	erb-b2 receptor tyrosine kinase 2	-4.0525
VGLL4	vestigial-like family member 4	-4.03695
RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1	-4.0298
PSRC1	proline/serine-rich coiled-coil 1	-4.02965
TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)	-4.01255
MRM3	mitochondrial rRNA methyltransferase 3	-4.0038
MYLK	myosin light chain kinase	-3.9847
TRPC4AP	transient receptor potential cation channel, subfamily C, member 4 associated protein	-3.98225
RNF220	ring finger protein 220	-3.9704
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	-3.96733
RNF4	ring finger protein 4	-3.95245
ILK	integrin-linked kinase	-3.94755
PUM2	pumilio RNA-binding family member 2	-3.93918
CTCF	CCCTC-binding factor (zinc finger protein)	-3.9198
FAT1	FAT atypical cadherin 1	-3.9092
MAPK6	mitogen-activated protein kinase 6	-3.88705
AXIN1	axin 1	-3.87655
RFC2	replication factor C (activator 1) 2, 40kDa	-3.87245
MAP2K4	mitogen-activated protein kinase kinase 4	-3.84483
CDC20	cell division cycle 20	-3.83145
KRT10	keratin 10, type I	-3.81183
TLCD3A	TLC domain containing 3A	-3.81155
ETFB	electron-transfer-flavoprotein, beta polypeptide	-3.79955
GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa	-3.797
RNPS1	RNA binding protein S1, serine-rich domain	-3.7888
CENPN	centromere protein N	-3.7868
RBM39	RNA binding motif protein 39	-3.772
CHERP	calcium homeostasis endoplasmic reticulum protein	-3.76192
IFRD2	interferon-related developmental regulator 2	-3.76162
RNASE7	ribonuclease, RNase A family, 7	-3.75955
MAEA	macrophage erythroblast attacher	-3.74385
FAM168B	family with sequence similarity 168, member B	-3.73885
SEC16A	SEC16 homolog A (S. cerevisiae)	-3.7337
PMP2	peripheral myelin protein 2	-3.7247
BAG2	BCL2-associated athanogene 2	-3.7206
DHX30	DEAH (Asp-Glu-Ala-His) box helicase 30	-3.70788
MSL1	male-specific lethal 1 homolog (Drosophila)	-3.70725
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	-3.6969
GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	-3.67927
RIOX1	ribosomal oxygenase 1	-3.67545
ATMIN	ATM interactor	-3.66645
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	-3.65495
FAM53C	family with sequence similarity 53, member C	-3.64905
SSUH2	ssu-2 homolog (C. elegans)	-3.63495
CHKA	choline kinase alpha	-3.63032
CYTH1	cytohesin 1	-3.62508
AATF	apoptosis antagonizing transcription factor	-3.6213
R3HCC1	R3H domain and coiled-coil containing 1	-3.61252
HAPSTR1	HUWE1 associated protein modifying stress responses	-3.60435
ZNF207	zinc finger protein 207	-3.59935
IER3	immediate early response 3	-3.5879
GEMIN4	gem (nuclear organelle) associated protein 4	-3.58665
LASP1	LIM and SH3 protein 1	-3.5683
THAP12	THAP domain containing 12	-3.55935
NCOA6	nuclear receptor coactivator 6	-3.5576
TEFM	transcription elongation factor, mitochondrial	-3.54565
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	-3.54545
MACF1	microtubule-actin crosslinking factor 1	-3.53331
PDF	peptide deformylase (mitochondrial)	-3.52955
SRSF3	serine/arginine-rich splicing factor 3	-3.51097
HMG20B	high mobility group 20B	-3.4952
BDH1	3-hydroxybutyrate dehydrogenase, type 1	-3.48505
ADAM10	ADAM metallopeptidase domain 10	-3.47423
GALE	UDP-galactose-4-epimerase	-3.45715
TIPIN	TIMELESS interacting protein	-3.4507
CEP76	centrosomal protein 76kDa	-3.45008
TBP	TATA box binding protein	-3.4365
CHMP7	charged multivesicular body protein 7	-3.4349
AKAP17A	A kinase (PRKA) anchor protein 17A	-3.43057
NUP85	nucleoporin 85kDa	-3.4249
CAPN7	calpain 7	-3.41945
NECAB3	N-terminal EF-hand calcium binding protein 3	-3.41295
IMPA2	inositol(myo)-1(or 4)-monophosphatase 2	-3.41145
MRPL18	mitochondrial ribosomal protein L18	-3.40075
NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor	-3.3882
ZNF263	zinc finger protein 263	-3.3828
NCBP3	nuclear cap binding subunit 3	-3.38115
MGA	MGA, MAX dimerization protein	-3.37555
DPF2	D4, zinc and double PHD fingers family 2	-3.3734
ARPP19	cAMP-regulated phosphoprotein, 19kDa	-3.36698
MBIP	MAP3K12 binding inhibitory protein 1	-3.361
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	-3.3505
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	-3.34875
NPR2	natriuretic peptide receptor 2	-3.33413
GTPBP6	GTP binding protein 6 (putative)	-3.33305
ANKRD17	ankyrin repeat domain 17	-3.28925
GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type	-3.2815
MED17	mediator complex subunit 17	-3.27465
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	-3.26765
UBP1	upstream binding protein 1 (LBP-1a)	-3.2616
CMC2	C-x(9)-C motif containing 2	-3.25525
ZBED1	zinc finger, BED-type containing 1	-3.2506
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	-3.24325
SYNGAP1	synaptic Ras GTPase activating protein 1	-3.23915
SLC25A46	solute carrier family 25, member 46	-3.22955
EML4	echinoderm microtubule associated protein like 4	-3.2254
UAP1	UDP-N-acetylglucosamine pyrophosphorylase 1	-3.1977
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	-3.1973
CHEK2	checkpoint kinase 2	-3.18935
MFAP1	microfibrillar-associated protein 1	-3.1889
FRAT2	frequently rearranged in advanced T-cell lymphomas 2	-3.1792
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	-3.17067
MARCKSL1	MARCKS-like 1	-3.16625
CHMP6	charged multivesicular body protein 6	-3.16225
RAB15	RAB15, member RAS oncogene family	-3.16225
PPP1R8	protein phosphatase 1, regulatory subunit 8	-3.15535
MTO1	mitochondrial tRNA translation optimization 1	-3.14928
SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2	-3.1492
ZNF672	zinc finger protein 672	-3.1491
DKK1	dickkopf WNT signaling pathway inhibitor 1	-3.1446
LRRC59	leucine rich repeat containing 59	-3.13385
ASXL1	additional sex combs like transcriptional regulator 1	-3.12875
NAE1	NEDD8 activating enzyme E1 subunit 1	-3.12815
TOP2B	topoisomerase (DNA) II beta 180kDa	-3.12705
CAAP1	caspase activity and apoptosis inhibitor 1	-3.12655
IGFBP4	insulin-like growth factor binding protein 4	-3.1165
TBC1D3G	TBC1 domain family member 3G	-3.11205
TUBG1	tubulin, gamma 1	-3.1091
TTC27	tetratricopeptide repeat domain 27	-3.10265
RBM25	RNA binding motif protein 25	-3.10155
TWF2	twinfilin actin binding protein 2	-3.10025
SMIM10L1	small integral membrane protein 10 like 1	-3.0856
ICAM3	intercellular adhesion molecule 3	-3.0829
PNRC2	proline-rich nuclear receptor coactivator 2	-3.08285
RTCB	RNA 2',3'-cyclic phosphate and 5'-OH ligase	-3.08225
TRAM2	translocation associated membrane protein 2	-3.0817
ERAL1	Era-like 12S mitochondrial rRNA chaperone 1	-3.07815
WIPF2	WAS/WASL interacting protein family, member 2	-3.06572
PHF10	PHD finger protein 10	-3.06565
LRRC47	leucine rich repeat containing 47	-3.0653
TXNRD1	thioredoxin reductase 1	-3.05725
MIS18BP1	MIS18 binding protein 1	-3.0523
DHX38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	-3.0483
TCP1	t-complex 1	-3.04782
DSG2	desmoglein 2	-3.04385
SLIRP	SRA stem-loop interacting RNA binding protein	-3.0434
SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like	-3.03665
PNN	pinin, desmosome associated protein	-3.03387
BCLAF1	BCL2-associated transcription factor 1	-3.02766
SRC	SRC proto-oncogene, non-receptor tyrosine kinase	-3.0154
PTBP1	polypyrimidine tract binding protein 1	-3.00918
MRPL46	mitochondrial ribosomal protein L46	-3.0088
PTS	6-pyruvoyltetrahydropterin synthase	-3.00865
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	-2.9903
KCTD9	potassium channel tetramerization domain containing 9	-2.9879
ZNF146	zinc finger protein 146	-2.98295
PUM1	pumilio RNA-binding family member 1	-2.97875
RRP1B	ribosomal RNA processing 1B	-2.97258
ZNF443	zinc finger protein 443	-2.97155
NPY	neuropeptide Y	-2.95925
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	-2.95905
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	-2.9581
TRIM28	tripartite motif containing 28	-2.95795
DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	-2.95755
NINJ2	ninjurin 2	-2.9556
MTUS1	microtubule associated tumor suppressor 1	-2.94877
LTF	lactotransferrin	-2.94855
SFPQ	splicing factor proline/glutamine-rich	-2.9424
MAT2A	methionine adenosyltransferase II, alpha	-2.93733
CCDC6	coiled-coil domain containing 6	-2.93525
NRBF2	nuclear receptor binding factor 2	-2.9332
MEX3C	mex-3 RNA binding family member C	-2.93265
TRIB3	tribbles pseudokinase 3	-2.9299
DUSP14	dual specificity phosphatase 14	-2.92015
PLAGL2	pleiomorphic adenoma gene-like 2	-2.91915
DHRS2	dehydrogenase/reductase (SDR family) member 2	-2.91753
SPATA2	spermatogenesis associated 2	-2.9155
KIF2C	kinesin family member 2C	-2.9079
MFN2	mitofusin 2	-2.90772
S100B	S100 calcium binding protein B	-2.9065
H2AX	H2A.X variant histone	-2.90615
ACOT2	acyl-CoA thioesterase 2	-2.90505
ARID4A	AT rich interactive domain 4A (RBP1-like)	-2.90375
PDCD2	programmed cell death 2	-2.8995
PRUNE1	prune exopolyphosphatase 1	-2.89762
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	-2.89655
GMFB	glia maturation factor, beta	-2.89485
ASNS	asparagine synthetase (glutamine-hydrolyzing)	-2.8913
POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	-2.8901
TRAPPC4	trafficking protein particle complex 4	-2.88812
KLHDC2	kelch domain containing 2	-2.88705
ACBD3	acyl-CoA binding domain containing 3	-2.88282
UBE2S	ubiquitin-conjugating enzyme E2S	-2.87975
TM9SF3	transmembrane 9 superfamily member 3	-2.8777
ARPC5L	actin related protein 2/3 complex, subunit 5-like	-2.8745
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	-2.87335
APOH	apolipoprotein H (beta-2-glycoprotein I)	-2.87075
FBXO34	F-box protein 34	-2.8623
TMEM115	transmembrane protein 115	-2.86055
PDS5A	PDS5 cohesin associated factor A	-2.85862
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	-2.84915
PLP1	proteolipid protein 1	-2.84745
MUL1	mitochondrial E3 ubiquitin protein ligase 1	-2.84325
GOLPH3	golgi phosphoprotein 3 (coat-protein)	-2.8402
THUMPD1	THUMP domain containing 1	-2.83722
NUP98	nucleoporin 98kDa	-2.83573
MVP	major vault protein	-2.835
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	-2.8349
RANGRF	RAN guanine nucleotide release factor	-2.8341
YTHDC1	YTH domain containing 1	-2.8309
COPB1	coatomer protein complex, subunit beta 1	-2.82835
SARS2	seryl-tRNA synthetase 2, mitochondrial	-2.8279
SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	-2.8262
SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	-2.8247
NELFB	negative elongation factor complex member B	-2.8238
SLIT2	slit homolog 2 (Drosophila)	-2.82375
SNIP1	Smad nuclear interacting protein 1	-2.8184
ALDH1A1	aldehyde dehydrogenase 1 family, member A1	-2.81665
CDC6	cell division cycle 6	-2.80985
SLC22A3	solute carrier family 22 (organic cation transporter), member 3	-2.797
TFE3	transcription factor binding to IGHM enhancer 3	-2.79553
OTUD3	OTU deubiquitinase 3	-2.7942
OXSR1	oxidative stress responsive 1	-2.79395
KMT5B	lysine methyltransferase 5B	-2.7937
CNOT7	CCR4-NOT transcription complex, subunit 7	-2.7875
RYBP	RING1 and YY1 binding protein	-2.7852
PRKCZ	protein kinase C, zeta	-2.78145
CDK2AP2	cyclin-dependent kinase 2 associated protein 2	-2.77925
EBNA1BP2	EBNA1 binding protein 2	-2.7788
SF1	splicing factor 1	-2.77865
SPAG4	sperm associated antigen 4	-2.775
YTHDF3	YTH N(6)-methyladenosine RNA binding protein 3	-2.7714
LOC128031832	uncharacterized LOC128031832	-2.76955
ERH	enhancer of rudimentary homolog (Drosophila)	-2.76865
DUSP6	dual specificity phosphatase 6	-2.76525
RCOR1	REST corepressor 1	-2.7651
LARS2	leucyl-tRNA synthetase 2, mitochondrial	-2.76485
GSTM5	glutathione S-transferase mu 5	-2.7606
SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	-2.76023
PSMG2	proteasome (prosome, macropain) assembly chaperone 2	-2.7572
EMC6	ER membrane protein complex subunit 6	-2.75695
CHMP1A	charged multivesicular body protein 1A	-2.7558
LANCL2	LanC lantibiotic synthetase component C-like 2 (bacterial)	-2.752
CH25H	cholesterol 25-hydroxylase	-2.7512
SENP6	SUMO1/sentrin specific peptidase 6	-2.74418
RBM15	RNA binding motif protein 15	-2.74235
FBXO11	F-box protein 11	-2.74203
FAM193A	family with sequence similarity 193, member A	-2.74145
DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10	-2.74055
ATG14	autophagy related 14	-2.73895
ENDOG	endonuclease G	-2.7367
NOL9	nucleolar protein 9	-2.73245
CAVIN2	caveolae associated protein 2	-2.73185
SS18L2	synovial sarcoma translocation gene on chromosome 18-like 2	-2.7257
TUBB4B	tubulin, beta 4B class IVb	-2.72205
INTS15	integrator complex subunit 15	-2.71042
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	-2.6969
YLPM1	YLP motif containing 1	-2.69288
ATF4	activating transcription factor 4	-2.6919
HNRNPM	heterogeneous nuclear ribonucleoprotein M	-2.6895
RPS27A	ribosomal protein S27a	-2.68715
WAPL	WAPL cohesin release factor	-2.68638
RELB	v-rel avian reticuloendotheliosis viral oncogene homolog B	-2.68485
UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	-2.6829
CDK5RAP1	CDK5 regulatory subunit associated protein 1	-2.6772
CLIC4	chloride intracellular channel 4	-2.67445
ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	-2.6743
MRFAP1L1	Morf4 family associated protein 1-like 1	-2.6738
DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	-2.6737
LAMA2	laminin, alpha 2	-2.66887
PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1	-2.6673
SQSTM1	sequestosome 1	-2.66427
IQGAP2	IQ motif containing GTPase activating protein 2	-2.6563
POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	-2.6489
FCHSD2	FCH and double SH3 domains 2	-2.6478
RBM7	RNA binding motif protein 7	-2.64695
RAB8A	RAB8A, member RAS oncogene family	-2.6431
PRNP	prion protein	-2.63916
PCDHGA5	protocadherin gamma subfamily A, 5	-2.6391
HYOU1	hypoxia up-regulated 1	-2.6375
JPT1	Jupiter microtubule associated homolog 1	-2.6371
CBLL1	Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase	-2.63695
COL9A3	collagen, type IX, alpha 3	-2.6359
PPP4R3A	protein phosphatase 4 regulatory subunit 3A	-2.63275
DLAT	dihydrolipoamide S-acetyltransferase	-2.63187
DAZAP1	DAZ associated protein 1	-2.63065
PCDH9	protocadherin 9	-2.63
EIF5	eukaryotic translation initiation factor 5	-2.62671
RTRAF	RNA transcription, translation and transport factor	-2.62475
RBM12	RNA binding motif protein 12	-2.6226
TUFM	Tu translation elongation factor, mitochondrial	-2.6216
S100P	S100 calcium binding protein P	-2.6196
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	-2.61775
GRSF1	G-rich RNA sequence binding factor 1	-2.61718
AGMAT	agmatine ureohydrolase (agmatinase)	-2.6169
TTC28	tetratricopeptide repeat domain 28	-2.61398
MYO5C	myosin VC	-2.61295
PSEN1	presenilin 1	-2.61175
WDR1	WD repeat domain 1	-2.60693
WDR6	WD repeat domain 6	-2.60415
GALNT10	polypeptide N-acetylgalactosaminyltransferase 10	-2.60215
MARCHF5	membrane associated ring-CH-type finger 5	-2.5965
MKRN2	makorin ring finger protein 2	-2.5938
PMPCA	peptidase (mitochondrial processing) alpha	-2.59375
TUBB4A	tubulin, beta 4A class IVa	-2.59005
SEC23IP	SEC23 interacting protein	-2.58872
TSPYL1	TSPY-like 1	-2.58855
KDM3A	lysine (K)-specific demethylase 3A	-2.5868
RAB5A	RAB5A, member RAS oncogene family	-2.58617
ACAA1	acetyl-CoA acyltransferase 1	-2.5826
PAQR6	progestin and adipoQ receptor family member VI	-2.5787
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	-2.57557
SETD1B	SET domain containing 1B	-2.57265
FMOD	fibromodulin	-2.5724
TMEM185B	transmembrane protein 185B	-2.5685
RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	-2.56635
CBFB	core-binding factor, beta subunit	-2.5652
BRD4	bromodomain containing 4	-2.5649
MPZL1	myelin protein zero-like 1	-2.56141
SRSF2	serine/arginine-rich splicing factor 2	-2.56102
CDK6	cyclin-dependent kinase 6	-2.5597
CKAP5	cytoskeleton associated protein 5	-2.5577
DBF4	DBF4 zinc finger	-2.55725
U2SURP	U2 snRNP-associated SURP domain containing	-2.55512
RAB11FIP2	RAB11 family interacting protein 2 (class I)	-2.55223
CGGBP1	CGG triplet repeat binding protein 1	-2.5494
CWC25	CWC25 spliceosome-associated protein homolog (S. cerevisiae)	-2.5465
TBC1D4	TBC1 domain family, member 4	-2.54565
YTHDF1	YTH N(6)-methyladenosine RNA binding protein 1	-2.54415
STOML2	stomatin (EPB72)-like 2	-2.54195
NFIL3	nuclear factor, interleukin 3 regulated	-2.5414
CENPT	centromere protein T	-2.54055
MALT1	MALT1 paracaspase	-2.53805
MSX1	msh homeobox 1	-2.5349
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	-2.53192
HOMER1	homer scaffolding protein 1	-2.53
UGDH	UDP-glucose 6-dehydrogenase	-2.5289
LOC124907782	dual specificity protein phosphatase 22	-2.5283
EXOSC9	exosome component 9	-2.52805
PPP4R3B	protein phosphatase 4 regulatory subunit 3B	-2.5273
SLC25A38	solute carrier family 25, member 38	-2.5238
TPX2	TPX2, microtubule-associated	-2.52365
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	-2.51878
NOP56	NOP56 ribonucleoprotein	-2.5168
MVB12B	multivesicular body subunit 12B	-2.51202
CLEC16A	C-type lectin domain family 16, member A	-2.5028
POLR2I	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	-2.49775
RALGAPB	Ral GTPase activating protein, beta subunit (non-catalytic)	-2.4878
HNRNPDL	heterogeneous nuclear ribonucleoprotein D-like	-2.48671
SEH1L	SEH1-like (S. cerevisiae)	-2.48565
MINDY1	MINDY lysine 48 deubiquitinase 1	-2.48505
PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	-2.48125
COA3	cytochrome c oxidase assembly factor 3	-2.4812
ARID4B	AT rich interactive domain 4B (RBP1-like)	-2.47995
NOL8	nucleolar protein 8	-2.47815
KDM5A	lysine (K)-specific demethylase 5A	-2.4749
BTBD3	BTB (POZ) domain containing 3	-2.4728
PPP4R1	protein phosphatase 4, regulatory subunit 1	-2.47255
ADNP	activity-dependent neuroprotector homeobox	-2.4724
ANAPC1	anaphase promoting complex subunit 1	-2.472
IGFBP1	insulin-like growth factor binding protein 1	-2.4717
SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1	-2.46902
TGFBR3	transforming growth factor, beta receptor III	-2.4686
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	-2.4676
AKAP10	A kinase (PRKA) anchor protein 10	-2.46495
SIAH2	siah E3 ubiquitin protein ligase 2	-2.4646
ATAD2	ATPase family, AAA domain containing 2	-2.4629
EPB41L2	erythrocyte membrane protein band 4.1-like 2	-2.46123
ZNHIT3	zinc finger, HIT-type containing 3	-2.4595
VTA1	vesicle (multivesicular body) trafficking 1	-2.45905
SMIM5	small integral membrane protein 5	-2.4509
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	-2.44843
NUP43	nucleoporin 43kDa	-2.4427
PAAF1	proteasomal ATPase-associated factor 1	-2.44215
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	-2.4366
CRISPLD2	cysteine-rich secretory protein LCCL domain containing 2	-2.43635
CHPT1	choline phosphotransferase 1	-2.4334
DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2	-2.4307
VPS51	vacuolar protein sorting 51 homolog (S. cerevisiae)	-2.4306
FKBP11	FK506 binding protein 11, 19 kDa	-2.42912
SCCPDH	saccharopine dehydrogenase (putative)	-2.42515
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	-2.42125
ZNF189	zinc finger protein 189	-2.4208
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	-2.4194
NEMF	nuclear export mediator factor	-2.4181
VCPKMT	valosin containing protein lysine (K) methyltransferase	-2.418
REXO4	REX4, RNA exonuclease 4 homolog (S. cerevisiae)	-2.41285
STX18	syntaxin 18	-2.4096
HSPA1A	heat shock 70kDa protein 1A	-2.40495
TSKU	tsukushi, small leucine rich proteoglycan	-2.40065
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	-2.39715
STIP1	stress-induced phosphoprotein 1	-2.39195
SPDL1	spindle apparatus coiled-coil protein 1	-2.3915
UTP6	UTP6, small subunit (SSU) processome component, homolog (yeast)	-2.3913
ZCCHC8	zinc finger, CCHC domain containing 8	-2.38865
ASF1A	anti-silencing function 1A histone chaperone	-2.38515
GNAS	GNAS complex locus	-2.38462
HKDC1	hexokinase domain containing 1	-2.3839
EXOC5	exocyst complex component 5	-2.3814
SEC23A	Sec23 homolog A (S. cerevisiae)	-2.37485
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	-2.37435
CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	-2.37375
NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	-2.37305
CRY1	cryptochrome circadian clock 1	-2.36335
ARHGAP19	Rho GTPase activating protein 19	-2.36185
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	-2.36095
ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	-2.36025
FNBP4	formin binding protein 4	-2.3595
PTX3	pentraxin 3, long	-2.3552
TJP2	tight junction protein 2	-2.35325
CENPA	centromere protein A	-2.35155
NLRX1	NLR family member X1	-2.3509
TRAK2	trafficking protein, kinesin binding 2	-2.35045
AP5M1	adaptor-related protein complex 5, mu 1 subunit	-2.34725
REV3L	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	-2.34655
UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X	-2.3428
GPKOW	G patch domain and KOW motifs	-2.34185
WDR33	WD repeat domain 33	-2.33885
SLC25A44	solute carrier family 25, member 44	-2.3364
PTBP3	polypyrimidine tract binding protein 3	-2.33492
ITPKA	inositol-trisphosphate 3-kinase A	-2.33405
ZC3H11B	zinc finger CCCH-type containing 11B pseudogene	-2.33247
SBNO1	strawberry notch homolog 1 (Drosophila)	-2.32675
IPPK	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	-2.32635
LARP4	La ribonucleoprotein domain family, member 4	-2.32597
TACC3	transforming, acidic coiled-coil containing protein 3	-2.3235
IPO7	importin 7	-2.32346
HOXA5	homeobox A5	-2.3223
CNN1	calponin 1, basic, smooth muscle	-2.3199
CHUK	conserved helix-loop-helix ubiquitous kinase	-2.3199
KAT2A	K(lysine) acetyltransferase 2A	-2.31935
PDCD5	programmed cell death 5	-2.3192
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	-2.318
ELAPOR1	endosome-lysosome associated apoptosis and autophagy regulator 1	-2.3156
LGR5	leucine-rich repeat containing G protein-coupled receptor 5	-2.31335
GAR1	GAR1 ribonucleoprotein	-2.30685
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	-2.3032
TMEM97	transmembrane protein 97	-2.29936
SIRT3	sirtuin 3	-2.29238
MRPL49	mitochondrial ribosomal protein L49	-2.28875
GPD1L	glycerol-3-phosphate dehydrogenase 1-like	-2.28805
ACTR10	actin-related protein 10 homolog (S. cerevisiae)	-2.2865
NARS1	asparaginyl-tRNA synthetase 1	-2.27865
NUBP2	nucleotide binding protein 2	-2.2772
SYNRG	synergin, gamma	-2.27638
GPSM2	G-protein signaling modulator 2	-2.27635
IARS1	isoleucyl-tRNA synthetase 1	-2.2763
TMEM267	transmembrane protein 267	-2.2738
SRP54	signal recognition particle 54kDa	-2.2722
HAUS3	HAUS augmin-like complex, subunit 3	-2.2715
SNW1	SNW domain containing 1	-2.26837
YARS1	tyrosyl-tRNA synthetase 1	-2.2673
RNF38	ring finger protein 38	-2.2637
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	-2.26332
FHOD1	formin homology 2 domain containing 1	-2.259
ABHD3	abhydrolase domain containing 3	-2.2574
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	-2.25435
RALY	RALY heterogeneous nuclear ribonucleoprotein	-2.25235
SCRG1	stimulator of chondrogenesis 1	-2.25005
VCP	valosin containing protein	-2.24857
PRPF39	pre-mRNA processing factor 39	-2.24585
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	-2.24581
LTN1	listerin E3 ubiquitin protein ligase 1	-2.245
DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	-2.24345
MED22	mediator complex subunit 22	-2.24275
RBM5	RNA binding motif protein 5	-2.24267
NDUFAF4	NADH dehydrogenase (ubiquinone) complex I, assembly factor 4	-2.2401
IER2	immediate early response 2	-2.23855
MAP2K2	mitogen-activated protein kinase kinase 2	-2.23815
SPTAN1	spectrin, alpha, non-erythrocytic 1	-2.23652
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	-2.23635
GEMIN2	gem (nuclear organelle) associated protein 2	-2.23406
TTC4	tetratricopeptide repeat domain 4	-2.23365
ZBTB11	zinc finger and BTB domain containing 11	-2.2316
ZZZ3	zinc finger, ZZ-type containing 3	-2.2315
VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)	-2.23095
CARMIL1	capping protein regulator and myosin 1 linker 1	-2.23035
KIAA0232	KIAA0232	-2.22725
GTF3C4	general transcription factor IIIC, polypeptide 4, 90kDa	-2.2236
GPATCH3	G patch domain containing 3	-2.22345
AACS	acetoacetyl-CoA synthetase	-2.22305
RHOF	ras homolog family member F (in filopodia)	-2.22225
PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	-2.21893
MOGAT2	monoacylglycerol O-acyltransferase 2	-2.21407
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	-2.21405
ELOVL6	ELOVL fatty acid elongase 6	-2.2129
MRPS17	mitochondrial ribosomal protein S17	-2.20835
EIF4E	eukaryotic translation initiation factor 4E	-2.20613
SF3B5	splicing factor 3b, subunit 5, 10kDa	-2.2032
ETV4	ets variant 4	-2.2016
CXCL8	chemokine (C-X-C motif) ligand 8	-2.2005
HNRNPR	heterogeneous nuclear ribonucleoprotein R	-2.20008
EIF4H	eukaryotic translation initiation factor 4H	-2.19875
RBM42	RNA binding motif protein 42	-2.1982
KIN	Kin17 DNA and RNA binding protein	-2.1957
CEP192	centrosomal protein 192kDa	-2.19025
METTL4	methyltransferase like 4	-2.18895
GGNBP2	gametogenetin binding protein 2	-2.18645
PYGB	phosphorylase, glycogen; brain	-2.18555
PRCC	papillary renal cell carcinoma (translocation-associated)	-2.1851
TNNC1	troponin C type 1 (slow)	-2.18447
IL32	interleukin 32	-2.18375
CEP43	centrosomal protein 43	-2.1819
GOLT1A	golgi transport 1A	-2.1812
SAFB	scaffold attachment factor B	-2.18078
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	-2.1787
MEN1	multiple endocrine neoplasia I	-2.17725
AREL1	apoptosis resistant E3 ubiquitin protein ligase 1	-2.1753
USP8	ubiquitin specific peptidase 8	-2.1739
NUP54	nucleoporin 54kDa	-2.1705
DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	-2.16665
MRPS35	mitochondrial ribosomal protein S35	-2.16513
GMPPA	GDP-mannose pyrophosphorylase A	-2.1637
DDX19A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A	-2.16152
ZDHHC7	zinc finger, DHHC-type containing 7	-2.1613
DEPDC1	DEP domain containing 1	-2.16115
TMX2	thioredoxin-related transmembrane protein 2	-2.16085
CASD1	CAS1 domain containing 1	-2.1607
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	-2.1589
PRPF8	pre-mRNA processing factor 8	-2.1588
BLTP3B	bridge-like lipid transfer protein family member 3B	-2.1563
ANKRD40	ankyrin repeat domain 40	-2.15535
UBE2G1	ubiquitin-conjugating enzyme E2G 1	-2.1531
FTH1	ferritin, heavy polypeptide 1	-2.15142
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	-2.14975
KDM1A	lysine (K)-specific demethylase 1A	-2.14665
MAPRE1	microtubule-associated protein, RP/EB family, member 1	-2.14398
CLTA	clathrin, light chain A	-2.1429
RAB22A	RAB22A, member RAS oncogene family	-2.1428
WDR18	WD repeat domain 18	-2.1408
CAVIN1	caveolae associated protein 1	-2.14015
ADD1	adducin 1 (alpha)	-2.13965
NUDC	nudC nuclear distribution protein	-2.13888
NDC80	NDC80 kinetochore complex component	-2.1365
FEM1B	fem-1 homolog b (C. elegans)	-2.13523
TERF2IP	telomeric repeat binding factor 2, interacting protein	-2.13425
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	-2.13297
NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	-2.1312
IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	-2.12585
IGF2R	insulin-like growth factor 2 receptor	-2.1258
NSD2	nuclear receptor binding SET domain protein 2	-2.1257
ZBTB24	zinc finger and BTB domain containing 24	-2.12335
ABCB8	ATP-binding cassette, sub-family B (MDR/TAP), member 8	-2.12135
ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	-2.1182
ARGLU1	arginine and glutamate rich 1	-2.11785
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	-2.11602
FHIP2B	FHF complex subunit HOOK interacting protein 2B	-2.11215
RBM28	RNA binding motif protein 28	-2.10955
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	-2.10927
RPP30	ribonuclease P/MRP 30kDa subunit	-2.1039
CNIH1	cornichon family AMPA receptor auxiliary protein 1	-2.10335
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	-2.10285
URGCP	upregulator of cell proliferation	-2.1026
TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	-2.10098
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	-2.0988
LPGAT1	lysophosphatidylglycerol acyltransferase 1	-2.09775
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	-2.09665
EIF3J	eukaryotic translation initiation factor 3, subunit J	-2.09562
CDR2	cerebellar degeneration-related protein 2, 62kDa	-2.09382
ZNF134	zinc finger protein 134	-2.0929
TNFRSF21	tumor necrosis factor receptor superfamily, member 21	-2.09113
CDC73	cell division cycle 73	-2.0898
ATP7B	ATPase, Cu++ transporting, beta polypeptide	-2.0896
SCRIB	scribbled planar cell polarity protein	-2.08915
GPX4	glutathione peroxidase 4	-2.0889
GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	-2.08555
SMTN	smoothelin	-2.08507
SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	-2.08461
REXO2	RNA exonuclease 2	-2.08254
XPO6	exportin 6	-2.08183
BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	-2.08095
SMG8	SMG8 nonsense mediated mRNA decay factor	-2.07955
PSAT1	phosphoserine aminotransferase 1	-2.0782
CARM1	coactivator-associated arginine methyltransferase 1	-2.0762
ARFGAP2	ADP-ribosylation factor GTPase activating protein 2	-2.0747
CDKN3	cyclin-dependent kinase inhibitor 3	-2.0741
SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	-2.07097
FGF7	fibroblast growth factor 7	-2.0704
POM121C	POM121 transmembrane nucleoporin C	-2.06775
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	-2.0677
TMPO	thymopoietin	-2.06563
SMYD5	SMYD family member 5	-2.0645
PIGH	phosphatidylinositol glycan anchor biosynthesis, class H	-2.06385
HSPA2	heat shock 70kDa protein 2	-2.06265
SLC43A1	solute carrier family 43 (amino acid system L transporter), member 1	-2.06185
FLNB	filamin B, beta	-2.05972
HSPE1	heat shock 10kDa protein 1	-2.05915
MRPS7	mitochondrial ribosomal protein S7	-2.059
FPGS	folylpolyglutamate synthase	-2.05885
DYNLRB1	dynein, light chain, roadblock-type 1	-2.0582
SRSF10	serine/arginine-rich splicing factor 10	-2.05789
DCP1A	decapping mRNA 1A	-2.05755
NFS1	NFS1 cysteine desulfurase	-2.05605
SMAP1	small ArfGAP 1	-2.056
METTL13	methyltransferase like 13	-2.05577
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	-2.0553
GPX2	glutathione peroxidase 2	-2.05465
EIF3B	eukaryotic translation initiation factor 3, subunit B	-2.05145
INTS13	integrator complex subunit 13	-2.05095
GTF2A2	general transcription factor IIA, 2, 12kDa	-2.048
RSRC2	arginine/serine-rich coiled-coil 2	-2.04763
SNUPN	snurportin 1	-2.0461
ZCCHC24	zinc finger, CCHC domain containing 24	-2.04603
SLC75A1	solute carrier family 75 member 1	-2.04545
KDM2A	lysine (K)-specific demethylase 2A	-2.04507
CDK17	cyclin-dependent kinase 17	-2.04437
CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	-2.04435
NRIP1	nuclear receptor interacting protein 1	-2.04307
GAB2	GRB2-associated binding protein 2	-2.04215
MYDGF	myeloid-derived growth factor	-2.04203
ARF6	ADP-ribosylation factor 6	-2.04185
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	-2.04175
UBE4A	ubiquitination factor E4A	-2.03995
GLG1	golgi glycoprotein 1	-2.03767
ECD	ecdysoneless homolog (Drosophila)	-2.03695
RNF126	ring finger protein 126	-2.03358
DTL	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	-2.03305
ANKRD10	ankyrin repeat domain 10	-2.0326
TSPYL4	TSPY-like 4	-2.0313
RAB23	RAB23, member RAS oncogene family	-2.0311
FAM111A	family with sequence similarity 111, member A	-2.03065
BMPR1B	bone morphogenetic protein receptor, type IB	-2.02785
ACACA	acetyl-CoA carboxylase alpha	-2.02763
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	-2.02745
CDK1	cyclin-dependent kinase 1	-2.02732
KCTD7	potassium channel tetramerization domain containing 7	-2.02415
NANS	N-acetylneuraminic acid synthase	-2.02285
NEK9	NIMA-related kinase 9	-2.0163
MRPL16	mitochondrial ribosomal protein L16	-2.0136
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	-2.01305
FEN1	flap structure-specific endonuclease 1	-2.01213
FBL	fibrillarin	-2.01185
FUBP3	far upstream element (FUSE) binding protein 3	-2.00955
TM4SF1	transmembrane 4 L six family member 1	-2.00889
PRMT1	protein arginine methyltransferase 1	-2.0084
CAB39	calcium binding protein 39	-2.0071
MT1H	metallothionein 1H	-2.00618
RAB5IF	RAB5 interacting factor	-2.0052
MID1IP1	MID1 interacting protein 1	-2.0049
SMG5	SMG5 nonsense mediated mRNA decay factor	-2.00143
GLDC	glycine dehydrogenase (decarboxylating)	-2.00055

Harmonizome 3.0

CRCGN014_HEPG2_24H:I12 Gene Set

Genes

increased expression

decreased expression

Please acknowledge the Harmonizome in your publications by citing the following reference(s):