CRCGN014_HEPG2_24H:I13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description felbamate 20.15 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1113 genes differentially expressed following the CRCGN014_HEPG2_24H:I13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EGF epidermal growth factor 10.0
E2F2 E2F transcription factor 2 10.0
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 10.0
RPL39L ribosomal protein L39-like 10.0
LCN2 lipocalin 2 10.0
CXCL2 chemokine (C-X-C motif) ligand 2 10.0
TIAM1 T-cell lymphoma invasion and metastasis 1 7.06213
CSK c-src tyrosine kinase 7.0545
CAPN1 calpain 1, (mu/I) large subunit 6.55525
DNM1 dynamin 1 6.1474
HLA-DMA major histocompatibility complex, class II, DM alpha 6.10905
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 6.10355
MYLK myosin light chain kinase 5.6625
CHN1 chimerin 1 5.58145
SYNGR3 synaptogyrin 3 5.5398
TAC4 tachykinin 4 (hemokinin) 5.5188
NANOS3 nanos homolog 3 (Drosophila) 5.51225
ADRB2 adrenoceptor beta 2, surface 5.21605
TREM1 triggering receptor expressed on myeloid cells 1 5.12525
PHKG2 phosphorylase kinase, gamma 2 (testis) 4.97275
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.88355
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 4.87845
RRAGA Ras-related GTP binding A 4.777
PPP4R3B protein phosphatase 4 regulatory subunit 3B 4.75425
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4.7174
C2CD2 C2 calcium-dependent domain containing 2 4.66275
NMU neuromedin U 4.66275
MUC1 mucin 1, cell surface associated 4.64282
LPAR2 lysophosphatidic acid receptor 2 4.628
IL1B interleukin 1, beta 4.54577
TIMP2 TIMP metallopeptidase inhibitor 2 4.53625
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 4.5145
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 4.4399
CBR3 carbonyl reductase 3 4.43475
HOXA10 homeobox A10 4.40968
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 4.36562
MAMLD1 mastermind-like domain containing 1 4.36215
CLCNKA chloride channel, voltage-sensitive Ka 4.32035
RXYLT1 ribitol xylosyltransferase 1 4.30748
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.29507
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.2855
ANO10 anoctamin 10 4.28195
ADGRA3 adhesion G protein-coupled receptor A3 4.18945
RAB4A RAB4A, member RAS oncogene family 4.18593
TRIL TLR4 interactor with leucine-rich repeats 4.12025
CBR1 carbonyl reductase 1 4.08585
TBP TATA box binding protein 4.02845
SNAP25 synaptosomal-associated protein, 25kDa 4.01435
SIM1 single-minded family bHLH transcription factor 1 3.9557
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 3.94878
HEBP1 heme binding protein 1 3.93855
CTRL chymotrypsin-like 3.8848
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 3.86265
GAS2 growth arrest-specific 2 3.83245
IFITM2 interferon induced transmembrane protein 2 3.7982
CLCN1 chloride channel, voltage-sensitive 1 3.79605
BPHL biphenyl hydrolase-like (serine hydrolase) 3.79515
UXS1 UDP-glucuronate decarboxylase 1 3.73545
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 3.71075
SCYL3 SCY1-like 3 (S. cerevisiae) 3.69357
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.67348
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.66775
FAM149A family with sequence similarity 149, member A 3.64898
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 3.63615
SYT1 synaptotagmin I 3.63167
GPATCH8 G patch domain containing 8 3.63055
CCDC85B coiled-coil domain containing 85B 3.5832
SH3GL2 SH3-domain GRB2-like 2 3.51795
ZNF165 zinc finger protein 165 3.50915
IL13 interleukin 13 3.505
VSNL1 visinin-like 1 3.49977
PHF14 PHD finger protein 14 3.49365
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 3.468
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 3.4647
DEFB1 defensin, beta 1 3.44905
PRKX protein kinase, X-linked 3.4437
CLCNKB chloride channel, voltage-sensitive Kb 3.4386
BAMBI BMP and activin membrane-bound inhibitor 3.43825
CTBP2 C-terminal binding protein 2 3.43405
IFITM3 interferon induced transmembrane protein 3 3.4339
RIN1 Ras and Rab interactor 1 3.42695
PROP1 PROP paired-like homeobox 1 3.4201
ORAI3 ORAI calcium release-activated calcium modulator 3 3.41655
FBRS fibrosin 3.4038
SIPA1 signal-induced proliferation-associated 1 3.3931
TNF tumor necrosis factor 3.39175
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 3.3897
MDM4 MDM4, p53 regulator 3.37845
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 3.3725
ARHGAP24 Rho GTPase activating protein 24 3.3608
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.3527
PRSS58 protease, serine, 58 3.34305
FBXL2 F-box and leucine-rich repeat protein 2 3.3387
ZC2HC1C zinc finger, C2HC-type containing 1C 3.33825
CPEB3 cytoplasmic polyadenylation element binding protein 3 3.3367
HLA-DRA major histocompatibility complex, class II, DR alpha 3.3343
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 3.31495
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 3.3092
THSD7A thrombospondin, type I, domain containing 7A 3.30105
CCNK cyclin K 3.28525
RPGRIP1L RPGRIP1-like 3.28315
CLPS colipase, pancreatic 3.2779
VPREB1 pre-B lymphocyte 1 3.2759
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 3.2607
MIS18BP1 MIS18 binding protein 1 3.2556
CELA2A chymotrypsin-like elastase family, member 2A 3.25242
HSPA1L heat shock 70kDa protein 1-like 3.2485
PLSCR1 phospholipid scramblase 1 3.2365
TAC1 tachykinin, precursor 1 3.2317
STUM stum, mechanosensory transduction mediator homolog 3.2292
INS insulin 3.21335
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 3.186
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 3.18235
MLANA melan-A 3.18197
BUB1B-PAK6 BUB1B-PAK6 readthrough 3.17363
GDF2 growth differentiation factor 2 3.1723
OLFML2B olfactomedin-like 2B 3.171
PNLIP pancreatic lipase 3.17
MRPL49 mitochondrial ribosomal protein L49 3.1655
DCN decorin 3.15062
RAB21 RAB21, member RAS oncogene family 3.1487
MAP9 microtubule-associated protein 9 3.11665
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 3.11125
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.09602
TET3 tet methylcytosine dioxygenase 3 3.0928
ZNF646 zinc finger protein 646 3.0876
EGR1 early growth response 1 3.08033
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 3.07125
PELI2 pellino E3 ubiquitin protein ligase family member 2 3.067
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 3.04315
CLDN6 claudin 6 3.03675
CPA1 carboxypeptidase A1 (pancreatic) 3.03165
ADGRA2 adhesion G protein-coupled receptor A2 3.03078
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 3.02305
RIMBP2 RIMS binding protein 2 3.02105
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 3.01525
NEIL1 nei endonuclease VIII-like 1 (E. coli) 3.01425
TYRP1 tyrosinase-related protein 1 3.00705
CEP152 centrosomal protein 152kDa 3.0052
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.00055
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.99793
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough 2.99507
TLE6 transducin-like enhancer of split 6 2.9942
KLF10 Kruppel-like factor 10 2.9893
GSTCD glutathione S-transferase, C-terminal domain containing 2.9889
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.98845
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.9784
LGSN lengsin, lens protein with glutamine synthetase domain 2.97665
UBE2A ubiquitin-conjugating enzyme E2A 2.96263
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 2.9617
KAT5 K(lysine) acetyltransferase 5 2.96088
OAZ3 ornithine decarboxylase antizyme 3 2.9599
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.9579
PAX9 paired box 9 2.9518
TMEM185B transmembrane protein 185B 2.95005
DNMBP dynamin binding protein 2.94865
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.9383
IL5 interleukin 5 2.9382
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.93414
SNAP91 synaptosomal-associated protein, 91kDa 2.9326
IL24 interleukin 24 2.9297
FRRS1L ferric-chelate reductase 1-like 2.9272
IL23A interleukin 23, alpha subunit p19 2.9272
PLXDC1 plexin domain containing 1 2.92625
GTF2A1 general transcription factor IIA, 1, 19/37kDa 2.92435
CLDN8 claudin 8 2.92365
HPSE2 heparanase 2 (inactive) 2.92165
DNAI7 dynein axonemal intermediate chain 7 2.92005
NPPA natriuretic peptide A 2.91985
UCMA upper zone of growth plate and cartilage matrix associated 2.9189
KLK1 kallikrein 1 2.9123
TOX thymocyte selection-associated high mobility group box 2.91095
COL3A1 collagen, type III, alpha 1 2.90565
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 2.90545
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 2.9051
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.89815
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.89395
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.88375
RAP2C RAP2C, member of RAS oncogene family 2.88242
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.8813
PLA2G12A phospholipase A2, group XIIA 2.8807
OLFML3 olfactomedin-like 3 2.87185
LAMA2 laminin, alpha 2 2.86778
ASXL3 additional sex combs like transcriptional regulator 3 2.86715
TMEM267 transmembrane protein 267 2.86625
CRH corticotropin releasing hormone 2.86503
PRSS53 protease, serine, 53 2.86215
PRDM2 PR domain containing 2, with ZNF domain 2.85885
LRRC8E leucine rich repeat containing 8 family, member E 2.8545
BBOF1 basal body orientation factor 1 2.85105
SHISAL1 shisa like 1 2.84812
HOXA11 homeobox A11 2.84777
SETD1A SET domain containing 1A 2.8466
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.8441
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.84105
PTPRG protein tyrosine phosphatase, receptor type, G 2.84025
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.83825
BTBD8 BTB (POZ) domain containing 8 2.83745
DEPTOR DEP domain containing MTOR-interacting protein 2.83525
VTCN1 V-set domain containing T cell activation inhibitor 1 2.83265
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.8258
TPST1 tyrosylprotein sulfotransferase 1 2.8226
NREP neuronal regeneration related protein 2.81982
SON SON DNA binding protein 2.81839
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.818
BBS10 Bardet-Biedl syndrome 10 2.81155
DPEP1 dipeptidase 1 (renal) 2.8036
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.7998
IFT70A intraflagellar transport 70A 2.79495
SASH3 SAM and SH3 domain containing 3 2.78875
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.78835
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.78605
IFNA6 interferon, alpha 6 2.78385
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.78235
IL3 interleukin 3 2.78145
KRT83 keratin 83, type II 2.77805
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.7774
NPHP1 nephronophthisis 1 (juvenile) 2.7753
COX5A cytochrome c oxidase subunit Va 2.77075
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 2.76982
EXPH5 exophilin 5 2.76758
HOXB2 homeobox B2 2.7653
CTAG2 cancer/testis antigen 2 2.76102
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.75705
TSPYL5 TSPY-like 5 2.75425
MAST3 microtubule associated serine/threonine kinase 3 2.7534
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 2.7491
EPCAM epithelial cell adhesion molecule 2.7465
DOP1A DOP1 leucine zipper like protein A 2.7452
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.7434
SST somatostatin 2.7384
TTBK2 tau tubulin kinase 2 2.7361
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.7242
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.72405
CUZD1 CUB and zona pellucida-like domains 1 2.72215
FHL5 four and a half LIM domains 5 2.722
ABHD18 abhydrolase domain containing 18 2.71115
DNM1L dynamin 1-like 2.7103
MBTD1 mbt domain containing 1 2.701
SSTR4 somatostatin receptor 4 2.69945
PNMA8A PNMA family member 8A 2.692
ZBTB10 zinc finger and BTB domain containing 10 2.69185
PENK proenkephalin 2.69015
CFAP298 cilia and flagella associated protein 298 2.68965
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.68765
ACTL7B actin-like 7B 2.68755
IFT22 intraflagellar transport 22 2.6874
MATN3 matrilin 3 2.6776
CST1 cystatin SN 2.67675
ANKRD37 ankyrin repeat domain 37 2.67655
ZNF669 zinc finger protein 669 2.6765
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.67615
MYOG myogenin (myogenic factor 4) 2.67285
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 2.67225
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.67178
STMN2 stathmin 2 2.66978
NT5DC3 5'-nucleotidase domain containing 3 2.6662
PUM1 pumilio RNA-binding family member 1 2.66455
HPN hepsin 2.65905
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.65785
PCOLCE procollagen C-endopeptidase enhancer 2.65715
SLC67A2 solute carrier family 67 member 2 2.65628
PRSS8 protease, serine, 8 2.65545
KL klotho 2.6548
HGD homogentisate 1,2-dioxygenase 2.65302
BRDT bromodomain, testis-specific 2.65285
SPTBN2 spectrin, beta, non-erythrocytic 2 2.6518
MAGEA9B melanoma antigen family A9B 2.64295
CXCL12 chemokine (C-X-C motif) ligand 12 2.6422
TYR tyrosinase 2.6401
RANBP6 RAN binding protein 6 2.63605
CENPO centromere protein O 2.6306
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.62355
DGUOK deoxyguanosine kinase 2.62122
PDZD8 PDZ domain containing 8 2.62105
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 2.6179
TCHH trichohyalin 2.6119
BZW2 basic leucine zipper and W2 domains 2 2.6097
EGR4 early growth response 4 2.60865
KDM4D lysine (K)-specific demethylase 4D 2.6056
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 2.5953
SRD5A3 steroid 5 alpha-reductase 3 2.59285
CD24 CD24 molecule 2.59207
ADGRD2 adhesion G protein-coupled receptor D2 2.5901
TSBP1 testis expressed basic protein 1 2.58665
RNF32 ring finger protein 32 2.5852
CAAP1 caspase activity and apoptosis inhibitor 1 2.5842
ERBB4 erb-b2 receptor tyrosine kinase 4 2.58315
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.58275
SNTA1 syntrophin, alpha 1 2.5825
ATP7A ATPase, Cu++ transporting, alpha polypeptide 2.58118
SPATA1 spermatogenesis associated 1 2.5798
CDKL3 cyclin-dependent kinase-like 3 2.57865
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.57772
PODXL2 podocalyxin-like 2 2.57635
RNF111 ring finger protein 111 2.57515
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.57515
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 2.57468
KIF26B kinesin family member 26B 2.57425
DCAF16 DDB1 and CUL4 associated factor 16 2.5724
SOCS4 suppressor of cytokine signaling 4 2.57085
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 2.57
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.5681
ASL argininosuccinate lyase 2.56585
ZBBX zinc finger, B-box domain containing 2.56535
ZFP2 ZFP2 zinc finger protein 2.56525
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 2.56243
MINAR1 membrane integral NOTCH2 associated receptor 1 2.5616
CTRC chymotrypsin C (caldecrin) 2.56105
KRTAP1-3 keratin associated protein 1-3 2.5588
DSG2 desmoglein 2 2.5573
AFTPH aftiphilin 2.554
LRRC8D leucine rich repeat containing 8 family, member D 2.5527
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.55125
PKD2L2 polycystic kidney disease 2-like 2 2.5508
NME5 NME/NM23 family member 5 2.5496
CALB1 calbindin 1, 28kDa 2.54955
FMO1 flavin containing monooxygenase 1 2.54915
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.5489
ZNF675 zinc finger protein 675 2.54545
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.54278
TRPC4 transient receptor potential cation channel, subfamily C, member 4 2.54247
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.53942
THY1 Thy-1 cell surface antigen 2.5356
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.5349
PACRG PARK2 co-regulated 2.53313
SCGB2A1 secretoglobin, family 2A, member 1 2.5293
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.5291
FGF16 fibroblast growth factor 16 2.5282
APOD apolipoprotein D 2.52685
SFTPB surfactant protein B 2.51518
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.5141
ZNF471 zinc finger protein 471 2.50275
PBOV1 prostate and breast cancer overexpressed 1 2.50135
SCGB1D2 secretoglobin, family 1D, member 2 2.501
CSN1S1 casein alpha s1 2.49485
TMEM131L transmembrane 131 like 2.49465
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 2.49288
DBN1 drebrin 1 2.48715
UBL3 ubiquitin-like 3 2.48418
SPATA6L spermatogenesis associated 6-like 2.48315
CYTH3 cytohesin 3 2.4822
PPP4R3A protein phosphatase 4 regulatory subunit 3A 2.48085
GSTM3 glutathione S-transferase mu 3 (brain) 2.4805
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.4799
DTNB dystrobrevin, beta 2.47738
IRAK3 interleukin-1 receptor-associated kinase 3 2.47543
PELI1 pellino E3 ubiquitin protein ligase 1 2.474
RBM22 RNA binding motif protein 22 2.4733
CALY calcyon neuron-specific vesicular protein 2.47255
TNP1 transition protein 1 (during histone to protamine replacement) 2.47205
LRRC37A3 leucine rich repeat containing 37, member A3 2.4689
PAPOLG poly(A) polymerase gamma 2.4687
LAPTM4B lysosomal protein transmembrane 4 beta 2.46862
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.46775
LEF1 lymphoid enhancer-binding factor 1 2.46598
THNSL2 threonine synthase-like 2 (S. cerevisiae) 2.46005
DUSP9 dual specificity phosphatase 9 2.46005
DAAM2 dishevelled associated activator of morphogenesis 2 2.4599
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.45928
ACVR2A activin A receptor, type IIA 2.4588
RIPOR2 RHO family interacting cell polarization regulator 2 2.45782
HHAT hedgehog acyltransferase 2.4571
LGI1 leucine-rich, glioma inactivated 1 2.45695
LYRM1 LYR motif containing 1 2.4557
CASR calcium-sensing receptor 2.45333
TMEM177 transmembrane protein 177 2.45065
LCMT2 leucine carboxyl methyltransferase 2 2.4494
E2F5 E2F transcription factor 5, p130-binding 2.4494
ATF7IP2 activating transcription factor 7 interacting protein 2 2.4468
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.44315
RNASET2 ribonuclease T2 2.43928
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.4381
JUP junction plakoglobin 2.43645
BSPRY B-box and SPRY domain containing 2.43555
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 2.43465
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 2.43235
GSG1 germ cell associated 1 2.4314
EPCIP exosomal polycystin 1 interacting protein 2.4299
PRRX2 paired related homeobox 2 2.42925
CTRB1 chymotrypsinogen B1 2.4281
OXCT1 3-oxoacid CoA transferase 1 2.42775
FAM184A family with sequence similarity 184, member A 2.42645
FSCN2 fascin actin-bundling protein 2, retinal 2.42645
SIKE1 suppressor of IKBKE 1 2.42515
CXCL3 chemokine (C-X-C motif) ligand 3 2.42485
NNAT neuronatin 2.42025
SKI SKI proto-oncogene 2.418
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.41715
MAGEB2 melanoma antigen family B2 2.41645
AFAP1 actin filament associated protein 1 2.41635
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2.4162
CAPNS1 calpain, small subunit 1 2.41475
DIABLO diablo, IAP-binding mitochondrial protein 2.4128
CMKLR2 chemerin chemokine-like receptor 2 2.4109
DAZ2 deleted in azoospermia 2 2.41047
AKAP8L A kinase (PRKA) anchor protein 8-like 2.4104
LTB4R leukotriene B4 receptor 2.40848
RNF2 ring finger protein 2 2.40445
CDC45 cell division cycle 45 2.4018
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.40025
ALPK3 alpha-kinase 3 2.39815
ZNF415 zinc finger protein 415 2.3931
PFN2 profilin 2 2.3931
FOXE3 forkhead box E3 2.393
SCIN scinderin 2.39135
HACD3 3-hydroxyacyl-CoA dehydratase 3 2.3887
RBM12B RNA binding motif protein 12B 2.38825
SETMAR SET domain and mariner transposase fusion gene 2.38655
STARD8 StAR-related lipid transfer (START) domain containing 8 2.384
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 2.3821
ANKRD36C ankyrin repeat domain 36C 2.38185
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.3816
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.38018
EXO5 exonuclease 5 2.37825
IRX5 iroquois homeobox 5 2.3757
GPER1 G protein-coupled estrogen receptor 1 2.3731
TPPP3 tubulin polymerization-promoting protein family member 3 2.3715
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 2.3708
MAP2K3 mitogen-activated protein kinase kinase 3 2.37015
SKAP1 src kinase associated phosphoprotein 1 2.36795
TRIM66 tripartite motif containing 66 2.36765
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.36715
SRSF9 serine/arginine-rich splicing factor 9 2.36165
ZNF234 zinc finger protein 234 2.3611
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 2.3602
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 2.36
TAS2R4 taste receptor, type 2, member 4 2.3578
RAB17 RAB17, member RAS oncogene family 2.3578
LOC107985101 uncharacterized LOC107985101 2.35775
ISG15 ISG15 ubiquitin-like modifier 2.35705
PLCH1 phospholipase C, eta 1 2.35237
BDKRB2 bradykinin receptor B2 2.3504
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.3479
UBQLN3 ubiquilin 3 2.3462
RPS9 ribosomal protein S9 2.34387
SLC16A6 solute carrier family 16, member 6 2.3426
TRIM58 tripartite motif containing 58 2.3425
FRAS1 Fraser extracellular matrix complex subunit 1 2.3425
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.34142
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 2.3411
PNLIPRP1 pancreatic lipase-related protein 1 2.33955
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 2.339
OTUD7B OTU deubiquitinase 7B 2.3355
WNT3 wingless-type MMTV integration site family, member 3 2.33415
MAB21L1 mab-21-like 1 (C. elegans) 2.32955
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.32905
STK24 serine/threonine kinase 24 2.32868
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.32695
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 2.3262
DNAH2 dynein, axonemal, heavy chain 2 2.32045
KLHL41 kelch-like family member 41 2.31815
AHCTF1 AT hook containing transcription factor 1 2.31815
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 2.31555
GLI1 GLI family zinc finger 1 2.31425
IL9 interleukin 9 2.3135
LDHAL6B lactate dehydrogenase A-like 6B 2.3132
PLP1 proteolipid protein 1 2.31305
RDH8 retinol dehydrogenase 8 (all-trans) 2.3106
MAP6D1 MAP6 domain containing 1 2.30985
DNAL4 dynein, axonemal, light chain 4 2.3096
CALCR calcitonin receptor 2.3088
CHSY1 chondroitin sulfate synthase 1 2.3077
NRXN3 neurexin 3 2.30762
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 2.30725
TSC22D4 TSC22 domain family, member 4 2.3062
LY6H lymphocyte antigen 6 complex, locus H 2.3054
FOXI1 forkhead box I1 2.30345
SLC22A17 solute carrier family 22, member 17 2.3025
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.30195
KRT31 keratin 31, type I 2.30165
DRC3 dynein regulatory complex subunit 3 2.3007
TJP3 tight junction protein 3 2.30032
MICB MHC class I polypeptide-related sequence B 2.2995
STK38 serine/threonine kinase 38 2.29875
PGAP6 post-GPI attachment to proteins 6 2.29775
RND1 Rho family GTPase 1 2.29455
SLC35F5 solute carrier family 35, member F5 2.29445
EHD1 EH-domain containing 1 2.29247
HOXB3 homeobox B3 2.2922
CLTCL1 clathrin, heavy chain-like 1 2.29205
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.28988
CAVIN3 caveolae associated protein 3 2.28935
SCAF4 SR-related CTD-associated factor 4 2.28825
TRIM68 tripartite motif containing 68 2.28645
HMG20A high mobility group 20A 2.28415
SCAMP2 secretory carrier membrane protein 2 2.2832
RBBP8 retinoblastoma binding protein 8 2.2797
UNKL unkempt family zinc finger-like 2.27965
NAP1L2 nucleosome assembly protein 1-like 2 2.27865
NUP210 nucleoporin 210kDa 2.2761
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 2.27505
KLHL2 kelch-like family member 2 2.2748
FBXO42 F-box protein 42 2.27455
RAB6B RAB6B, member RAS oncogene family 2.27453
CH25H cholesterol 25-hydroxylase 2.2742
GP5 glycoprotein V (platelet) 2.27292
SCAND1 SCAN domain containing 1 2.2727
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.27165
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 2.26772
ZMYM2 zinc finger, MYM-type 2 2.26762
ND5 NADH dehydrogenase subunit 5 2.2676
TULP4 tubby like protein 4 2.2674
TOR1AIP2 torsin A interacting protein 2 2.26715
PADI4 peptidyl arginine deiminase, type IV 2.26627
KRT12 keratin 12, type I 2.26585
ULK1 unc-51 like autophagy activating kinase 1 2.265
ZNF257 zinc finger protein 257 2.2636
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.2632
CASS4 Cas scaffolding protein family member 4 2.26265
KIF24 kinesin family member 24 2.26175
PSME4 proteasome (prosome, macropain) activator subunit 4 2.26088
AOC1 amine oxidase, copper containing 1 2.2606
BHMT2 betaine--homocysteine S-methyltransferase 2 2.26
FES FES proto-oncogene, tyrosine kinase 2.2582
FGF17 fibroblast growth factor 17 2.25515
COL14A1 collagen, type XIV, alpha 1 2.25467
PRLR prolactin receptor 2.25374
ZNF208 zinc finger protein 208 2.2514
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.2467
ADGRE3 adhesion G protein-coupled receptor E3 2.24615
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 2.24395
CUEDC1 CUE domain containing 1 2.24225
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.24225
VCAN versican 2.24223
FAT4 FAT atypical cadherin 4 2.23975
USP34 ubiquitin specific peptidase 34 2.2382
PDE7B phosphodiesterase 7B 2.2365
CELA2B chymotrypsin-like elastase family, member 2B 2.2357
DNASE1 deoxyribonuclease I 2.23485
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 2.23043
PHC2 polyhomeotic homolog 2 (Drosophila) 2.23
PEX5L peroxisomal biogenesis factor 5-like 2.23
SIRT4 sirtuin 4 2.2296
SFRP1 secreted frizzled-related protein 1 2.22872
TSPYL4 TSPY-like 4 2.2275
TNN tenascin N 2.22725
MEGF9 multiple EGF-like-domains 9 2.22675
F13A1 coagulation factor XIII, A1 polypeptide 2.2236
IL10 interleukin 10 2.22225
GSTM5 glutathione S-transferase mu 5 2.222
GAS7 growth arrest-specific 7 2.22161
FGB fibrinogen beta chain 2.21777
CXCL8 chemokine (C-X-C motif) ligand 8 2.21658
VEZT vezatin, adherens junctions transmembrane protein 2.2165
PF4V1 platelet factor 4 variant 1 2.21625
PRAME preferentially expressed antigen in melanoma 2.2162
ITSN1 intersectin 1 (SH3 domain protein) 2.21561
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.2154
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 2.21481
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.2146
TWIST1 twist family bHLH transcription factor 1 2.21375
PGR progesterone receptor 2.21305
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.2116
SNU13 small nuclear ribonucleoprotein 13 2.2109
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.2101
STC1 stanniocalcin 1 2.20978
CTSK cathepsin K 2.20815
MEX3C mex-3 RNA binding family member C 2.20745
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 2.20652
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 2.2055
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2.20432
DNAAF1 dynein, axonemal, assembly factor 1 2.20393
ZNF440 zinc finger protein 440 2.2022
MYOD1 myogenic differentiation 1 2.20095
LCAT lecithin-cholesterol acyltransferase 2.2005
CRYBA2 crystallin, beta A2 2.19825
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 2.1965
CEP104 centrosomal protein 104kDa 2.19455
CRY1 cryptochrome circadian clock 1 2.194
LPO lactoperoxidase 2.1939
SLC16A4 solute carrier family 16, member 4 2.19325
PAX2 paired box 2 2.19208
SETD4 SET domain containing 4 2.1893
GLI3 GLI family zinc finger 3 2.1882
EPHA3 EPH receptor A3 2.18785
SIRT3 sirtuin 3 2.18755
SP3 Sp3 transcription factor 2.1862
SRPX2 sushi-repeat containing protein, X-linked 2 2.1854
NOX3 NADPH oxidase 3 2.1851
TUBB2B tubulin, beta 2B class IIb 2.184
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.1839
CRYL1 crystallin, lambda 1 2.1822
PTPRN protein tyrosine phosphatase, receptor type, N 2.182
SMAGP small cell adhesion glycoprotein 2.1814
F8A2 coagulation factor VIII-associated 2 2.18125
PAQR3 progestin and adipoQ receptor family member III 2.1802
SCGB2A2 secretoglobin, family 2A, member 2 2.18005
SNTG2 syntrophin, gamma 2 2.1798
CFAP43 cilia and flagella associated protein 43 2.1778
MROH9 maestro heat-like repeat family member 9 2.1767
UCN urocortin 2.1751
NPY neuropeptide Y 2.17465
SH3D19 SH3 domain containing 19 2.17397
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.173
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.171
COL18A1 collagen, type XVIII, alpha 1 2.1706
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 2.16755
CCDC198 coiled-coil domain containing 198 2.16675
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 2.1652
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.1651
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.16415
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.161
PCDHGA3 protocadherin gamma subfamily A, 3 2.1609
CELA3A chymotrypsin-like elastase family, member 3A 2.16073
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 2.16065
GAMT guanidinoacetate N-methyltransferase 2.16
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.15915
KCNK2 potassium channel, two pore domain subfamily K, member 2 2.1557
UNC93A unc-93 homolog A (C. elegans) 2.15175
SPRED2 sprouty-related, EVH1 domain containing 2 2.15145
CD248 CD248 molecule, endosialin 2.1484
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.14715
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 2.14637
CD99 CD99 molecule 2.14617
AGTR2 angiotensin II receptor, type 2 2.14465
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 2.1446
CFAP68 cilia and flagella associated protein 68 2.1444
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.14395
ZFTA zinc finger translocation associated 2.14375
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.14345
PALMD palmdelphin 2.14255
ADGB androglobin 2.14215
CTRB2 chymotrypsinogen B2 2.142
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.1419
TRHDE thyrotropin-releasing hormone degrading enzyme 2.14135
LOC124903372 uncharacterized LOC124903372 2.14038
LYST lysosomal trafficking regulator 2.14012
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.13835
KAT6A K(lysine) acetyltransferase 6A 2.138
GOLM1 golgi membrane protein 1 2.1368
ZNF609 zinc finger protein 609 2.13657
CEP70 centrosomal protein 70kDa 2.13525
ZNF764 zinc finger protein 764 2.135
FAM110A family with sequence similarity 110, member A 2.13465
PDLIM2 PDZ and LIM domain 2 (mystique) 2.13135
ZNF682 zinc finger protein 682 2.13055
ZNF80 zinc finger protein 80 2.1296
EGR3 early growth response 3 2.12925
SOX3 SRY (sex determining region Y)-box 3 2.1289
ZNF492 zinc finger protein 492 2.1284
ZNF780B zinc finger protein 780B 2.12825
CRELD2 cysteine-rich with EGF-like domains 2 2.1277
PCDHB1 protocadherin beta 1 2.12725
LRRC17 leucine rich repeat containing 17 2.1263
BEST1 bestrophin 1 2.12605
HCRT hypocretin (orexin) neuropeptide precursor 2.12585
SOCS5 suppressor of cytokine signaling 5 2.12545
ESR2 estrogen receptor 2 (ER beta) 2.12529
WNT2 wingless-type MMTV integration site family member 2 2.1246
PLAA phospholipase A2-activating protein 2.12357
GPR12 G protein-coupled receptor 12 2.1234
CLUH clustered mitochondria (cluA/CLU1) homolog 2.1209
NINL ninein-like 2.1208
TLL1 tolloid-like 1 2.11995
RBKS ribokinase 2.11735
SNX16 sorting nexin 16 2.1167
LOC100996750 keratin-associated protein 4-7 2.1154
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.11535
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.1145
MMP11 matrix metallopeptidase 11 2.1143
AGBL2 ATP/GTP binding protein-like 2 2.1142
MLXIP MLX interacting protein 2.114
IL4 interleukin 4 2.11378
PRLH prolactin releasing hormone 2.11275
TFIP11 tuftelin interacting protein 11 2.11158
IGFALS insulin-like growth factor binding protein, acid labile subunit 2.11025
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2.10773
LATS1 large tumor suppressor kinase 1 2.1071
RTL10 retrotransposon Gag like 10 2.107
JMJD1C jumonji domain containing 1C 2.1062
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.10545
FPR1 formyl peptide receptor 1 2.10407
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.103
ESRRG estrogen-related receptor gamma 2.10185
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.1014
DKKL1 dickkopf-like 1 2.1007
RORB RAR-related orphan receptor B 2.0997
GMIP GEM interacting protein 2.0996
HOXA6 homeobox A6 2.0993
FAM13C family with sequence similarity 13, member C 2.0988
CCNE1 cyclin E1 2.09725
EEA1 early endosome antigen 1 2.09685
LPA lipoprotein, Lp(a) 2.09555
ZNF214 zinc finger protein 214 2.09475
IFNA5 interferon, alpha 5 2.0937
NBPF10 neuroblastoma breakpoint family, member 10 2.0925
VPREB3 pre-B lymphocyte 3 2.0916
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.09029
LRP2 low density lipoprotein receptor-related protein 2 2.09
FKBP6 FK506 binding protein 6, 36kDa 2.0898
MUC16 mucin 16, cell surface associated 2.08945
BPIFA1 BPI fold containing family A, member 1 2.08935
GPATCH2L G patch domain containing 2-like 2.0877
ZNF460 zinc finger protein 460 2.0869
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.08665
CHODL chondrolectin 2.0855
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2.08455
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 2.0843
GCG glucagon 2.08405
ACOXL acyl-CoA oxidase-like 2.0836
MSTN myostatin 2.0829
TCP11 t-complex 11, testis-specific 2.08145
HMGN2 high mobility group nucleosomal binding domain 2 2.08145
NECTIN4 nectin cell adhesion molecule 4 2.08075
MAGEA2B melanoma antigen family A2B 2.07845
GTF2H2C GTF2H2 family member C 2.07802
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.07785
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.07768
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.07725
MRPS18C mitochondrial ribosomal protein S18C 2.07705
ESRP1 epithelial splicing regulatory protein 1 2.0769
ZNF81 zinc finger protein 81 2.07605
HOXA2 homeobox A2 2.0756
MYO3A myosin IIIA 2.07385
CCNO cyclin O 2.0736
HOXA3 homeobox A3 2.0729
CDH20 cadherin 20, type 2 2.0726
NEFM neurofilament, medium polypeptide 2.0721
FKBP14 FK506 binding protein 14, 22 kDa 2.07185
GULP1 GULP, engulfment adaptor PTB domain containing 1 2.06747
AMPH amphiphysin 2.06725
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.0661
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.06595
SYT2 synaptotagmin II 2.0657
RBM4 RNA binding motif protein 4 2.06568
CCDC121 coiled-coil domain containing 121 2.06545
TIGD6 tigger transposable element derived 6 2.0654
UNC119B unc-119 homolog B (C. elegans) 2.0651
ZNF548 zinc finger protein 548 2.06485
KRT23 keratin 23, type I 2.06285
MAGEA10 melanoma antigen family A10 2.0627
ZNF287 zinc finger protein 287 2.06205
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.06165
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.06115
STAMBP STAM binding protein 2.0608
PLPPR4 phospholipid phosphatase related 4 2.0599
PRKN parkin RBR E3 ubiquitin protein ligase 2.05895
ATXN2L ataxin 2-like 2.05845
GREB1 growth regulation by estrogen in breast cancer 1 2.05792
NOL9 nucleolar protein 9 2.053
TAS2R10 taste receptor, type 2, member 10 2.0512
RNF216 ring finger protein 216 2.05088
RPA4 replication protein A4, 30kDa 2.0506
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.05005
PLAGL1 pleiomorphic adenoma gene-like 1 2.04985
MAGEB1 melanoma antigen family B1 2.04973
ZNF493 zinc finger protein 493 2.04965
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.0496
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.0492
BMP2K BMP2 inducible kinase 2.04895
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.0487
GPX7 glutathione peroxidase 7 2.04635
RAB1A RAB1A, member RAS oncogene family 2.04582
BLTP2 bridge-like lipid transfer protein family member 2 2.04478
CATSPERZ catsper channel auxiliary subunit zeta 2.044
WDR5B WD repeat domain 5B 2.0439
SH3BP1 SH3-domain binding protein 1 2.04335
ENDOU endonuclease, polyU-specific 2.0431
PER2 period circadian clock 2 2.04293
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.04055
HROB homologous recombination factor with OB-fold 2.0393
ANKMY1 ankyrin repeat and MYND domain containing 1 2.0388
KMT2B lysine (K)-specific methyltransferase 2B 2.03735
PRM2 protamine 2 2.0365
HSPB1 heat shock 27kDa protein 1 2.03535
FCAR Fc fragment of IgA receptor 2.03534
DISC1 disrupted in schizophrenia 1 2.03527
TRPC3 transient receptor potential cation channel, subfamily C, member 3 2.03513
FOXJ1 forkhead box J1 2.0335
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2.03052
PCSK2 proprotein convertase subtilisin/kexin type 2 2.0289
CEND1 cell cycle exit and neuronal differentiation 1 2.0284
JARID2 jumonji, AT rich interactive domain 2 2.02833
F2R coagulation factor II (thrombin) receptor 2.0283
EML1 echinoderm microtubule associated protein like 1 2.02695
BTC betacellulin 2.02695
COL15A1 collagen, type XV, alpha 1 2.02675
AIG1 androgen-induced 1 2.02585
ALPK1 alpha-kinase 1 2.0254
CPNE7 copine VII 2.0252
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.02455
BRS3 bombesin-like receptor 3 2.02435
ZNF391 zinc finger protein 391 2.0237
SRPX sushi-repeat containing protein, X-linked 2.02175
UNC119 unc-119 homolog (C. elegans) 2.0209
AKIRIN1 akirin 1 2.0209
SSTR2 somatostatin receptor 2 2.02023
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.01995
RPGR retinitis pigmentosa GTPase regulator 2.0198
BBC3 BCL2 binding component 3 2.01735
WDFY3 WD repeat and FYVE domain containing 3 2.0165
RBP1 retinol binding protein 1, cellular 2.0152
GMDS GDP-mannose 4,6-dehydratase 2.01307
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.01155
MTRF1L mitochondrial translational release factor 1-like 2.01055
PLCL1 phospholipase C-like 1 2.00905
UMOD uromodulin 2.00895
KIAA0319 KIAA0319 2.0084
KRTAP9-9 keratin associated protein 9-9 2.00825
KLHL29 kelch-like family member 29 2.0081
DLK1 delta-like 1 homolog (Drosophila) 2.0064
DENND1C DENN/MADD domain containing 1C 2.0061
DEFB126 defensin, beta 126 2.0056
MEIS1 Meis homeobox 1 2.00545
ZNF749 zinc finger protein 749 2.0051
LOC128966570 alpha-amylase 1B 2.0044
COQ8B coenzyme Q8B 2.0039
DPF2 D4, zinc and double PHD fingers family 2 2.00295
NR2C2 nuclear receptor subfamily 2, group C, member 2 2.00285
MMP13 matrix metallopeptidase 13 2.0025
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.0015

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -9.44255
ZW10 zw10 kinetochore protein -7.32775
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -6.6305
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -6.44275
SYNE2 spectrin repeat containing, nuclear envelope 2 -6.39835
HYOU1 hypoxia up-regulated 1 -6.3567
CRYZ crystallin, zeta (quinone reductase) -6.01195
ISOC1 isochorismatase domain containing 1 -5.8411
THAP11 THAP domain containing 11 -5.83865
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -5.78835
ZDHHC6 zinc finger, DHHC-type containing 6 -5.73245
COG4 component of oligomeric golgi complex 4 -5.71055
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.6884
NT5DC2 5'-nucleotidase domain containing 2 -5.5759
ACOT9 acyl-CoA thioesterase 9 -5.55505
BLMH bleomycin hydrolase -5.55425
TOMM34 translocase of outer mitochondrial membrane 34 -5.401
LDHD lactate dehydrogenase D -5.0801
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.0
SPAG4 sperm associated antigen 4 -4.85485
GSTM2 glutathione S-transferase mu 2 (muscle) -4.83362
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.81435
PCNA proliferating cell nuclear antigen -4.75515
KDM3A lysine (K)-specific demethylase 3A -4.73695
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.69505
GOLT1B golgi transport 1B -4.6445
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.60995
NCK1 NCK adaptor protein 1 -4.5181
NUP85 nucleoporin 85kDa -4.50395
GTPBP8 GTP-binding protein 8 (putative) -4.4569
PRKCD protein kinase C, delta -4.40615
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.3027
ARID5B AT rich interactive domain 5B (MRF1-like) -4.07165
RFC2 replication factor C (activator 1) 2, 40kDa -4.04635
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.00895
CHEK1 checkpoint kinase 1 -3.94885
TMEM94 transmembrane protein 94 -3.93375
RPIA ribose 5-phosphate isomerase A -3.8945
YME1L1 YME1-like 1 ATPase -3.86592
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -3.77758
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.77285
TDP2 tyrosyl-DNA phosphodiesterase 2 -3.7524
TM9SF3 transmembrane 9 superfamily member 3 -3.72705
TCTN1 tectonic family member 1 -3.6878
WBP2 WW domain binding protein 2 -3.687
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -3.65715
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.6409
ACAA1 acetyl-CoA acyltransferase 1 -3.62665
DYNLT3 dynein, light chain, Tctex-type 3 -3.6236
RBM34 RNA binding motif protein 34 -3.60723
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -3.60585
DCSTAMP dendrocyte expressed seven transmembrane protein -3.57565
RECQL RecQ helicase-like -3.56756
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.5555
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -3.53618
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -3.5158
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -3.49885
NOL11 nucleolar protein 11 -3.49225
LAP3 leucine aminopeptidase 3 -3.488
SLC35F2 solute carrier family 35, member F2 -3.4669
ECD ecdysoneless homolog (Drosophila) -3.4611
PLEK2 pleckstrin 2 -3.4562
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -3.43305
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -3.422
HMG20B high mobility group 20B -3.41803
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.35515
JUN jun proto-oncogene -3.338
WARS1 tryptophanyl-tRNA synthetase 1 -3.32207
GSTO1 glutathione S-transferase omega 1 -3.3031
BHLHE41 basic helix-loop-helix family, member e41 -3.29235
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -3.27295
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -3.2226
CDC25B cell division cycle 25B -3.2089
NME3 NME/NM23 nucleoside diphosphate kinase 3 -3.1926
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.1842
MRPS16 mitochondrial ribosomal protein S16 -3.1719
KCTD2 potassium channel tetramerization domain containing 2 -3.15905
RBM15B RNA binding motif protein 15B -3.14725
MRPS7 mitochondrial ribosomal protein S7 -3.13755
CHMP4B charged multivesicular body protein 4B -3.1317
HEXB hexosaminidase B (beta polypeptide) -3.1158
CCNB1 cyclin B1 -3.11495
SKIC3 SKI3 subunit of superkiller complex -3.0865
RAP1GAP RAP1 GTPase activating protein -3.0735
RAB13 RAB13, member RAS oncogene family -3.06965
PCID2 PCI domain containing 2 -3.0585
NAE1 NEDD8 activating enzyme E1 subunit 1 -3.04355
CD58 CD58 molecule -3.01588
TMEM214 transmembrane protein 214 -3.0046
GSTM4 glutathione S-transferase mu 4 -2.9866
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.9748
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.9723
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.9646
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.95175
SELENOW selenoprotein W -2.94305
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.93745
RPN1 ribophorin I -2.9368
FABP4 fatty acid binding protein 4, adipocyte -2.92715
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.9231
COMMD8 COMM domain containing 8 -2.9176
EFNB1 ephrin-B1 -2.9042
MRPL58 mitochondrial ribosomal protein L58 -2.90125
SPDEF SAM pointed domain containing ETS transcription factor -2.89062
SERINC3 serine incorporator 3 -2.88395
TMX1 thioredoxin-related transmembrane protein 1 -2.8582
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.8446
CERK ceramide kinase -2.84055
C4A complement component 4A (Rodgers blood group) -2.83825
NCOA6 nuclear receptor coactivator 6 -2.83425
CD3D CD3d molecule, delta (CD3-TCR complex) -2.8245
CHIT1 chitinase 1 (chitotriosidase) -2.8231
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.8153
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) -2.77275
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -2.76985
VTA1 vesicle (multivesicular body) trafficking 1 -2.766
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.75495
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.74605
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.74585
GRN granulin -2.74305
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.7017
MFSD1 major facilitator superfamily domain containing 1 -2.69635
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.69525
FBXO46 F-box protein 46 -2.6769
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -2.67345
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -2.66155
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.661
PPDPF pancreatic progenitor cell differentiation and proliferation factor -2.65825
POGLUT1 protein O-glucosyltransferase 1 -2.64815
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -2.64485
NVL nuclear VCP-like -2.63905
BMAL2 basic helix-loop-helix ARNT like 2 -2.63785
ZZZ3 zinc finger, ZZ-type containing 3 -2.63135
CA9 carbonic anhydrase IX -2.61495
PECR peroxisomal trans-2-enoyl-CoA reductase -2.61375
ZBTB38 zinc finger and BTB domain containing 38 -2.61295
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.61205
GABARAPL2 GABA(A) receptor-associated protein-like 2 -2.60885
MSH2 mutS homolog 2 -2.6065
S100A4 S100 calcium binding protein A4 -2.6012
SLC38A6 solute carrier family 38, member 6 -2.5999
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -2.59885
FGR FGR proto-oncogene, Src family tyrosine kinase -2.5868
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.57632
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.57158
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.57002
MCOLN1 mucolipin 1 -2.5602
TSPAN13 tetraspanin 13 -2.55155
HMGN4 high mobility group nucleosomal binding domain 4 -2.53825
PRDX4 peroxiredoxin 4 -2.53745
ARCN1 archain 1 -2.5327
IL32 interleukin 32 -2.53075
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.52185
KLF4 Kruppel-like factor 4 (gut) -2.51605
CAMLG calcium modulating ligand -2.5126
GLRX2 glutaredoxin 2 -2.49275
NIT1 nitrilase 1 -2.49245
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.48255
FDXR ferredoxin reductase -2.48175
FICD FIC domain containing -2.4734
RPE ribulose-5-phosphate-3-epimerase -2.47057
RNF13 ring finger protein 13 -2.47022
APOL3 apolipoprotein L, 3 -2.4593
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -2.45845
PCDHGB6 protocadherin gamma subfamily B, 6 -2.45627
FANCE Fanconi anemia, complementation group E -2.4434
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.4405
PNKP polynucleotide kinase 3'-phosphatase -2.4251
APOC1 apolipoprotein C-I -2.4162
ANKRD10 ankyrin repeat domain 10 -2.40445
TRAPPC4 trafficking protein particle complex 4 -2.40142
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -2.3994
WDR76 WD repeat domain 76 -2.3969
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -2.37242
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -2.36345
HIKESHI heat shock protein nuclear import factor hikeshi -2.3607
KARS1 lysyl-tRNA synthetase 1 -2.35773
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -2.3576
BORA bora, aurora kinase A activator -2.35545
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.35235
MCM3 minichromosome maintenance complex component 3 -2.35165
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.3435
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.34273
MUTYH mutY homolog -2.33955
SOAT2 sterol O-acyltransferase 2 -2.33857
LMO4 LIM domain only 4 -2.31857
SLAMF8 SLAM family member 8 -2.3139
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.312
USO1 USO1 vesicle transport factor -2.30905
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -2.29815
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.29535
LCK LCK proto-oncogene, Src family tyrosine kinase -2.29137
TRIM23 tripartite motif containing 23 -2.29112
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.2832
SLAMF7 SLAM family member 7 -2.27435
ADSS2 adenylosuccinate synthase 2 -2.26655
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.26345
SUMO4 small ubiquitin-like modifier 4 -2.2618
HOXB13 homeobox B13 -2.25665
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -2.25605
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.25385
CD52 CD52 molecule -2.25292
GBP1 guanylate binding protein 1, interferon-inducible -2.2507
GSAP gamma-secretase activating protein -2.2477
GRB7 growth factor receptor-bound protein 7 -2.2445
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.24443
GPN3 GPN-loop GTPase 3 -2.24415
MRPL48 mitochondrial ribosomal protein L48 -2.2432
GBP2 guanylate binding protein 2, interferon-inducible -2.23655
COMMD10 COMM domain containing 10 -2.2357
BMP2 bone morphogenetic protein 2 -2.22255
PKN1 protein kinase N1 -2.22237
FCHO1 FCH domain only 1 -2.2223
RPAP3 RNA polymerase II associated protein 3 -2.2206
NDC80 NDC80 kinetochore complex component -2.216
OXSR1 oxidative stress responsive 1 -2.2152
AVPI1 arginine vasopressin-induced 1 -2.2151
CORO1B coronin, actin binding protein, 1B -2.21168
TMEM134 transmembrane protein 134 -2.21105
BCAP31 B-cell receptor-associated protein 31 -2.2086
MRPL34 mitochondrial ribosomal protein L34 -2.2041
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.20375
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.2022
SECISBP2 SECIS binding protein 2 -2.2018
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.1904
TMEM50A transmembrane protein 50A -2.18615
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.18275
LZTR1 leucine-zipper-like transcription regulator 1 -2.17985
MED22 mediator complex subunit 22 -2.1784
RAP2A RAP2A, member of RAS oncogene family -2.1753
IRF8 interferon regulatory factor 8 -2.16785
ITGB1BP1 integrin beta 1 binding protein 1 -2.16582
RTCA RNA 3'-terminal phosphate cyclase -2.1658
AIDA axin interactor, dorsalization associated -2.16555
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -2.16364
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.16225
FERMT1 fermitin family member 1 -2.16162
STIMATE STIM activating enhancer -2.15885
INCENP inner centromere protein antigens 135/155kDa -2.1522
MRPL39 mitochondrial ribosomal protein L39 -2.15205
SYNGAP1 synaptic Ras GTPase activating protein 1 -2.15105
KXD1 KxDL motif containing 1 -2.1503
SRPK3 SRSF protein kinase 3 -2.14865
TWF1 twinfilin actin binding protein 1 -2.14818
PA2G4 proliferation-associated 2G4, 38kDa -2.14405
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.14395
MATK megakaryocyte-associated tyrosine kinase -2.1354
CDC123 cell division cycle 123 -2.1344
PALM2AKAP2 PALM2 and AKAP2 fusion -2.1301
CEPT1 choline/ethanolamine phosphotransferase 1 -2.128
PWP1 PWP1 homolog (S. cerevisiae) -2.11647
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.11632
MOSPD2 motile sperm domain containing 2 -2.10888
FAT1 FAT atypical cadherin 1 -2.1072
TRIM37 tripartite motif containing 37 -2.10625
BABAM1 BRISC and BRCA1 A complex member 1 -2.1036
TMEM126B transmembrane protein 126B -2.102
NCKIPSD NCK interacting protein with SH3 domain -2.1005
CTSS cathepsin S -2.08862
IGFLR1 IGF-like family receptor 1 -2.0885
YIPF5 Yip1 domain family, member 5 -2.0882
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.08667
PTS 6-pyruvoyltetrahydropterin synthase -2.08615
NOL8 nucleolar protein 8 -2.08535
NFS1 NFS1 cysteine desulfurase -2.0823
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.078
ACOX1 acyl-CoA oxidase 1, palmitoyl -2.07405
NUCB1 nucleobindin 1 -2.07177
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -2.06915
ACOT8 acyl-CoA thioesterase 8 -2.06795
RPP40 ribonuclease P/MRP 40kDa subunit -2.0669
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.06375
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.0563
RHOC ras homolog family member C -2.0554
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -2.05105
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -2.04482
AADAC arylacetamide deacetylase -2.0446
INTS13 integrator complex subunit 13 -2.0444
ANXA13 annexin A13 -2.0423
SMG8 SMG8 nonsense mediated mRNA decay factor -2.0407
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -2.0383
TXNL4B thioredoxin-like 4B -2.0367
CTSW cathepsin W -2.0354
ZNHIT6 zinc finger, HIT-type containing 6 -2.03455
IFNAR1 interferon (alpha, beta and omega) receptor 1 -2.033
SIRPA signal-regulatory protein alpha -2.03017
GYS1 glycogen synthase 1 (muscle) -2.02795
ATP9A ATPase, class II, type 9A -2.0253
MMP9 matrix metallopeptidase 9 -2.0247
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.02425
ABHD6 abhydrolase domain containing 6 -2.02303
FN3KRP fructosamine 3 kinase related protein -2.0192
GPC4 glypican 4 -2.01815
IL2RG interleukin 2 receptor, gamma -2.01575
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -2.01565
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.01335
ANOS1 anosmin 1 -2.01265
NANS N-acetylneuraminic acid synthase -2.0111
CLEC10A C-type lectin domain family 10, member A -2.0106
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -2.01
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.00335
SCFD1 sec1 family domain containing 1 -2.0026