CRCGN014_HEPG2_24H:I16 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_24H:I16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.2899
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.5227
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.29744
|
|
SATB1
|
SATB homeobox 1
|
3.9581
|
|
MAP7
|
microtubule-associated protein 7
|
3.62873
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.58433
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
3.44359
|
|
CYCS
|
cytochrome c, somatic
|
3.3179
|
|
CHN1
|
chimerin 1
|
3.28884
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.02705
|
|
LCN2
|
lipocalin 2
|
3.01881
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.8636
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.75268
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.72776
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.62562
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.5861
|
|
UBQLN2
|
ubiquilin 2
|
2.43077
|
|
MYLK
|
myosin light chain kinase
|
2.42425
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.34868
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.34732
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.27166
|
|
PCMT1
|
protein-L-isoaspartate (D-aspartate) O-methyltransferase
|
2.23362
|
|
SFTPB
|
surfactant protein B
|
2.22177
|
|
CCNF
|
cyclin F
|
2.21172
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.15308
|
|
CLDN16
|
claudin 16
|
2.14274
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.08768
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-7.31892
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-7.05371
|
|
PCNA
|
proliferating cell nuclear antigen
|
-7.0337
|
|
LDHD
|
lactate dehydrogenase D
|
-6.91564
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.27205
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.10846
|
|
RNF167
|
ring finger protein 167
|
-3.36154
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.31583
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.30281
|
|
DNM1L
|
dynamin 1-like
|
-3.28504
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.80788
|
|
SIAH2
|
siah E3 ubiquitin protein ligase 2
|
-2.50157
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.49432
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.43257
|
|
ZNF586
|
zinc finger protein 586
|
-2.35167
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.27441
|
|
LIN37
|
lin-37 DREAM MuvB core complex component
|
-2.14643
|
|
RBBP7
|
retinoblastoma binding protein 7
|
-2.10282
|
|
CCNB2
|
cyclin B2
|
-2.08358
|
|
AHSP
|
alpha hemoglobin stabilizing protein
|
-2.02787
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.01865
|
