CRCGN014_HEPG2_24H:I22 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.32879
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
5.96271
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.96992
|
|
EPHB2
|
EPH receptor B2
|
4.75895
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.70999
|
|
SMIM40
|
small integral membrane protein 40
|
4.68331
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.60848
|
|
MYLK
|
myosin light chain kinase
|
4.55623
|
|
CBR3
|
carbonyl reductase 3
|
4.50966
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.56699
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.13778
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.09665
|
|
NMU
|
neuromedin U
|
2.75925
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.71021
|
|
JADE2
|
jade family PHD finger 2
|
2.27976
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
2.17168
|
|
CHN1
|
chimerin 1
|
2.12888
|
|
PCCA
|
propionyl CoA carboxylase, alpha polypeptide
|
2.1216
|
|
STXBP2
|
syntaxin binding protein 2
|
2.05199
|
|
HERC5
|
HECT and RLD domain containing E3 ubiquitin protein ligase 5
|
2.02258
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.33345
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.98149
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.20122
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.5705
|
|
GNAS
|
GNAS complex locus
|
-3.37804
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.16016
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.92197
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.91252
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.72785
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.63515
|
|
ZNF586
|
zinc finger protein 586
|
-2.63289
|
|
TLR4
|
toll-like receptor 4
|
-2.33129
|
|
ADGRG6
|
adhesion G protein-coupled receptor G6
|
-2.2271
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.21566
|
|
ILF2
|
interleukin enhancer binding factor 2
|
-2.12511
|
|
ATRN
|
attractin
|
-2.06983
|
|
ZNF219
|
zinc finger protein 219
|
-2.05201
|
