CRCGN014_HEPG2_24H:I23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-diethyl o-(4-nitrophenyl) thiophosphate 21.22 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN014_HEPG2_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 4.82547
CBR3 carbonyl reductase 3 4.81043
E2F2 E2F transcription factor 2 4.59142
CIAO3 cytosolic iron-sulfur assembly component 3 4.45718
C2CD2 C2 calcium-dependent domain containing 2 3.80642
LOC122526780 uncharacterized LOC122526780 3.8019
STK10 serine/threonine kinase 10 3.70394
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.64287
PFKL phosphofructokinase, liver 3.60456
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.59506
CEMIP2 cell migration inducing hyaluronidase 2 2.54463
PCNT pericentrin 2.39705
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.38866
EPHA3 EPH receptor A3 2.29672
SCRN1 secernin 1 2.21741
LOC102724652 alpha-crystallin A chain 2.1643
CCNF cyclin F 2.0264

decreased expression

Symbol Name Standardized Value
MRPS2 mitochondrial ribosomal protein S2 -5.13374
TRIB3 tribbles pseudokinase 3 -4.84533
LDHD lactate dehydrogenase D -4.84315
THAP11 THAP domain containing 11 -4.69452
HAT1 histone acetyltransferase 1 -4.0643
FASTKD5 FAST kinase domains 5 -4.03232
TMEM109 transmembrane protein 109 -3.83473
ILK integrin-linked kinase -3.78164
TLR4 toll-like receptor 4 -3.50794
FGFR4 fibroblast growth factor receptor 4 -2.96173
MAPK13 mitogen-activated protein kinase 13 -2.89214
RGS2 regulator of G-protein signaling 2 -2.7903
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.30292
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.29001
OXA1L oxidase (cytochrome c) assembly 1-like -2.15498
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.15479
ADI1 acireductone dioxygenase 1 -2.13976
RBM34 RNA binding motif protein 34 -2.08711
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.00451