| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triphenylphosphine oxide 20.12 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN014_HEPG2_24H:J02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 7.5237 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.20044 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.05173 |
| E2F2 | E2F transcription factor 2 | 4.54794 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.51129 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.46154 |
| CAPN1 | calpain 1, (mu/I) large subunit | 4.42405 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.42267 |
| STIMATE | STIM activating enhancer | 3.80405 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.69644 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.54991 |
| IDE | insulin-degrading enzyme | 3.48573 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.40969 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 3.36524 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.2582 |
| CCNF | cyclin F | 3.16959 |
| HEBP1 | heme binding protein 1 | 3.10836 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.98201 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.91382 |
| GPATCH8 | G patch domain containing 8 | 2.87715 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.74329 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.57914 |
| HEBP2 | heme binding protein 2 | 2.57503 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 2.46486 |
| SATB1 | SATB homeobox 1 | 2.46317 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.32717 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | 2.24665 |
| JADE2 | jade family PHD finger 2 | 2.1797 |
| MAPK3 | mitogen-activated protein kinase 3 | 2.1481 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.14556 |
| GRAMD1B | GRAM domain containing 1B | 2.00045 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NT5DC2 | 5'-nucleotidase domain containing 2 | -9.57748 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -5.92121 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.6962 |
| LDHD | lactate dehydrogenase D | -4.45517 |
| CHMP4B | charged multivesicular body protein 4B | -4.25347 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -4.23253 |
| CDC20 | cell division cycle 20 | -4.1969 |
| UBE3C | ubiquitin protein ligase E3C | -4.04284 |
| CCNB2 | cyclin B2 | -3.96978 |
| YME1L1 | YME1-like 1 ATPase | -3.59944 |
| NISCH | nischarin | -3.16957 |
| EGF | epidermal growth factor | -3.0134 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.01259 |
| RPS5 | ribosomal protein S5 | -2.9431 |
| RAI14 | retinoic acid induced 14 | -2.42878 |
| TES | testin LIM domain protein | -2.42824 |
| TLR4 | toll-like receptor 4 | -2.41236 |
| MPO | myeloperoxidase | -2.37237 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.31324 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -2.30311 |
| METTL8 | methyltransferase like 8 | -2.26965 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -2.25817 |
| ATF5 | activating transcription factor 5 | -2.2189 |
| OLFML2A | olfactomedin-like 2A | -2.20595 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.18895 |
| SHROOM2 | shroom family member 2 | -2.18068 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.13948 |
| GRN | granulin | -2.10476 |
| CA2 | carbonic anhydrase II | -2.10382 |
| SCG5 | secretogranin V | -2.04665 |
| PCNA | proliferating cell nuclear antigen | -2.0398 |
