| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3,3'-dimethoxybenzidine.2hcl 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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45 genes differentially expressed following the CRCGN014_HEPG2_24H:J04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 4.2283 |
| DDIT4 | DNA-damage-inducible transcript 4 | 4.02425 |
| TRIB3 | tribbles pseudokinase 3 | 3.68679 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.62542 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.26132 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.92261 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.64526 |
| MPC2 | mitochondrial pyruvate carrier 2 | 2.58918 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.55681 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.54661 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.47758 |
| ICAM1 | intercellular adhesion molecule 1 | 2.4412 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.432 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 2.41392 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.3407 |
| PHGDH | phosphoglycerate dehydrogenase | 2.32112 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.30027 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.22151 |
| LCN2 | lipocalin 2 | 2.14575 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.12056 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 2.06669 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.03313 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.01815 |
| KMT5B | lysine methyltransferase 5B | 2.00631 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLT1B | golgi transport 1B | -4.76837 |
| CDC25B | cell division cycle 25B | -4.39168 |
| ADI1 | acireductone dioxygenase 1 | -4.24295 |
| ZNF586 | zinc finger protein 586 | -3.30187 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.11195 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.10911 |
| CD58 | CD58 molecule | -3.06321 |
| CCNB2 | cyclin B2 | -3.01428 |
| HMG20B | high mobility group 20B | -2.95998 |
| LDHD | lactate dehydrogenase D | -2.86117 |
| TCTN1 | tectonic family member 1 | -2.72302 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.62487 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.46076 |
| EDN1 | endothelin 1 | -2.41692 |
| SNX11 | sorting nexin 11 | -2.3717 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.3106 |
| PPOX | protoporphyrinogen oxidase | -2.27856 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.09605 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.08225 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -2.01203 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.01087 |
