CRCGN014_HEPG2_24H:J07 Gene Set
Genes
32 genes differentially expressed following the CRCGN014_HEPG2_24H:J07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.89996
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.06035
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.86384
|
|
EGF
|
epidermal growth factor
|
3.72486
|
|
ANO10
|
anoctamin 10
|
3.43718
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.408
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.39925
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.24256
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.20422
|
|
CHEK2
|
checkpoint kinase 2
|
2.63788
|
|
LCN2
|
lipocalin 2
|
2.54729
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.5316
|
|
GATA2
|
GATA binding protein 2
|
2.31433
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
2.12803
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.10266
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.018
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.00352
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-4.6529
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.81496
|
|
ZNF586
|
zinc finger protein 586
|
-3.75734
|
|
LDHD
|
lactate dehydrogenase D
|
-3.26196
|
|
TSPAN4
|
tetraspanin 4
|
-3.23996
|
|
CDC20
|
cell division cycle 20
|
-3.16557
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.16537
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.07643
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.9579
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.81582
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.71796
|
|
SPAG4
|
sperm associated antigen 4
|
-2.52486
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.38753
|
|
SNX11
|
sorting nexin 11
|
-2.15128
|
|
TMPRSS3
|
transmembrane protease, serine 3
|
-2.08531
|
