| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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48 genes differentially expressed following the CRCGN014_HEPG2_24H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 7.19409 |
| FZD7 | frizzled class receptor 7 | 6.09704 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.96755 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.65756 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.9781 |
| ABHD6 | abhydrolase domain containing 6 | 3.44147 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.42798 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.19971 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.9955 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.98443 |
| EPHA3 | EPH receptor A3 | 2.79877 |
| ZNF589 | zinc finger protein 589 | 2.75456 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.71882 |
| MAMLD1 | mastermind-like domain containing 1 | 2.67896 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.60691 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.60115 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.4755 |
| CEP57 | centrosomal protein 57kDa | 2.4528 |
| EVL | Enah/Vasp-like | 2.37872 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.255 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.21137 |
| NOSIP | nitric oxide synthase interacting protein | 2.09181 |
| RWDD3 | RWD domain containing 3 | 2.0616 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.05217 |
| TOE1 | target of EGR1, member 1 (nuclear) | 2.02477 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.00495 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -6.97635 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -4.72399 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.31249 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.13218 |
| PCNA | proliferating cell nuclear antigen | -3.83764 |
| LDHD | lactate dehydrogenase D | -3.73329 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.45805 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.992 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.98224 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.94367 |
| ZNF586 | zinc finger protein 586 | -2.85324 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.82656 |
| CCNB2 | cyclin B2 | -2.66617 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.65876 |
| PLK1 | polo-like kinase 1 | -2.65658 |
| TLR4 | toll-like receptor 4 | -2.49999 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.47852 |
| RAI14 | retinoic acid induced 14 | -2.16602 |
| YME1L1 | YME1-like 1 ATPase | -2.14576 |
| ADI1 | acireductone dioxygenase 1 | -2.13306 |
| TES | testin LIM domain protein | -2.08669 |
| MTA1 | metastasis associated 1 | -2.07302 |
