CRCGN014_HEPG2_24H:J12 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
3.76432
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
3.56039
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.52768
|
|
NOTCH1
|
notch 1
|
3.24213
|
|
CHN1
|
chimerin 1
|
3.20684
|
|
EGF
|
epidermal growth factor
|
3.17399
|
|
MYLK
|
myosin light chain kinase
|
3.11458
|
|
LCN2
|
lipocalin 2
|
3.0793
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.02162
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.01563
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.99524
|
|
EPN2
|
epsin 2
|
2.47789
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.4532
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.28951
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.25
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.20775
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.15915
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.34448
|
|
DNM1L
|
dynamin 1-like
|
-6.73232
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.04904
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-4.42318
|
|
LDHD
|
lactate dehydrogenase D
|
-3.38103
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.08737
|
|
ZNF586
|
zinc finger protein 586
|
-2.96459
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.96057
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.93464
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.55311
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.54766
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.52373
|
|
SPAG4
|
sperm associated antigen 4
|
-2.33082
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.2809
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.20026
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.17828
|
|
TLR4
|
toll-like receptor 4
|
-2.14924
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.04422
|
