CRCGN014_HEPG2_24H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 20.99 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the CRCGN014_HEPG2_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 9.18819
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.95266
E2F2 E2F transcription factor 2 4.65524
KLHL21 kelch-like family member 21 4.5218
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.17842
PRR15L proline rich 15-like 4.15449
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.97962
LPAR2 lysophosphatidic acid receptor 2 3.95431
NOSIP nitric oxide synthase interacting protein 3.72873
ZFP36 ZFP36 ring finger protein 3.41812
HOXA10 homeobox A10 3.33263
RXYLT1 ribitol xylosyltransferase 1 2.99955
TRAK2 trafficking protein, kinesin binding 2 2.96398
GPATCH8 G patch domain containing 8 2.79784
EVL Enah/Vasp-like 2.59499
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.45647
CCNF cyclin F 2.44588
RAB21 RAB21, member RAS oncogene family 2.44066
LOC122526780 uncharacterized LOC122526780 2.31155
GADD45A growth arrest and DNA-damage-inducible, alpha 2.26618
SATB1 SATB homeobox 1 2.19087
NUCB2 nucleobindin 2 2.18569
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.12365
KIF20A kinesin family member 20A 2.1148
SCGB2A1 secretoglobin, family 2A, member 1 2.05812
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.03222

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -4.89486
SLC35F2 solute carrier family 35, member F2 -4.87923
PCNA proliferating cell nuclear antigen -4.6406
NRIP1 nuclear receptor interacting protein 1 -4.32913
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.92792
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.42971
MAPK13 mitogen-activated protein kinase 13 -3.34496
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.8476
PDZD2 PDZ domain containing 2 -2.82997
TLR4 toll-like receptor 4 -2.77137
PRPF4 pre-mRNA processing factor 4 -2.69041
RNF167 ring finger protein 167 -2.53233
LOC124907782 dual specificity protein phosphatase 22 -2.29467
FASTKD5 FAST kinase domains 5 -2.27146
TCTN1 tectonic family member 1 -2.20019
SEC61B Sec61 beta subunit -2.11365
ITGB1BP1 integrin beta 1 binding protein 1 -2.09962
MCF2L MCF.2 cell line derived transforming sequence-like -2.09223
APOE apolipoprotein E -2.0747
NVL nuclear VCP-like -2.04791
ICAM3 intercellular adhesion molecule 3 -2.0478
ZNF586 zinc finger protein 586 -2.03528