CRCGN014_HEPG2_24H:J16 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.38482
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.75354
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.27903
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
3.13413
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.12362
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.08528
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.06205
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.98463
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.94383
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.92383
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
2.67314
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.45523
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
2.44774
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.42714
|
|
MAP7
|
microtubule-associated protein 7
|
2.42472
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
2.30471
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.29173
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.23722
|
|
PRR15L
|
proline rich 15-like
|
2.17394
|
|
CDC45
|
cell division cycle 45
|
2.118
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.09772
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.0077
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.19414
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.54931
|
|
CCNB2
|
cyclin B2
|
-5.02194
|
|
ZNF586
|
zinc finger protein 586
|
-4.36989
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.59334
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
-3.44499
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.83168
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.75478
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.65672
|
|
CDC25B
|
cell division cycle 25B
|
-2.6092
|
|
DNMT1
|
DNA (cytosine-5-)-methyltransferase 1
|
-2.5095
|
|
LDHD
|
lactate dehydrogenase D
|
-2.45982
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
-2.42796
|
|
FHL2
|
four and a half LIM domains 2
|
-2.4029
|
|
CDK1
|
cyclin-dependent kinase 1
|
-2.38326
|
|
BMP4
|
bone morphogenetic protein 4
|
-2.27504
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.23479
|
|
PLK1
|
polo-like kinase 1
|
-2.22454
|
|
VAT1
|
vesicle amine transport 1
|
-2.15624
|
|
RNF167
|
ring finger protein 167
|
-2.1541
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.08533
|
|
U2AF2
|
U2 small nuclear RNA auxiliary factor 2
|
-2.05244
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
-2.01374
|
|
CDC20
|
cell division cycle 20
|
-2.01162
|
