CRCGN014_HEPG2_24H:J20 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.0895
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
4.08535
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.61018
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.45185
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.2324
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.05503
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.03813
|
|
FZD7
|
frizzled class receptor 7
|
2.98271
|
|
NOTCH1
|
notch 1
|
2.96076
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.88344
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.78533
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.67087
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.53097
|
|
GPATCH8
|
G patch domain containing 8
|
2.34766
|
|
SIRT3
|
sirtuin 3
|
2.31582
|
|
PRR15L
|
proline rich 15-like
|
2.28867
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.2691
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.16383
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.12201
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.02216
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.88003
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.63682
|
|
CCNB2
|
cyclin B2
|
-3.54611
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.53179
|
|
ZNF586
|
zinc finger protein 586
|
-3.31399
|
|
PLK1
|
polo-like kinase 1
|
-3.11878
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.09245
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.76069
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.55395
|
|
GDF15
|
growth differentiation factor 15
|
-2.47102
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.45164
|
|
MTA1
|
metastasis associated 1
|
-2.38484
|
|
LDHD
|
lactate dehydrogenase D
|
-2.36271
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.35204
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.04614
|
|
RNF167
|
ring finger protein 167
|
-2.02185
|
