| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,5-dithiobiurea 39.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
62 genes differentially expressed following the CRCGN014_HEPG2_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAMLD1 | mastermind-like domain containing 1 | 7.9539 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 7.86654 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 5.43448 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 4.93266 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.52209 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.43522 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.27029 |
| UBQLN2 | ubiquilin 2 | 4.08751 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.95469 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.8698 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.82262 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.60562 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.34879 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.15915 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.98071 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.93352 |
| PRKCH | protein kinase C, eta | 2.78889 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.76103 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.74629 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 2.66051 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.45226 |
| ZNF589 | zinc finger protein 589 | 2.44968 |
| FZD7 | frizzled class receptor 7 | 2.4229 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.31566 |
| MAP7 | microtubule-associated protein 7 | 2.31278 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.27903 |
| SQOR | sulfide quinone oxidoreductase | 2.23383 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.18976 |
| NOSIP | nitric oxide synthase interacting protein | 2.18598 |
| DZIP1 | DAZ interacting zinc finger protein 1 | 2.16181 |
| LCN2 | lipocalin 2 | 2.05576 |
| CHN1 | chimerin 1 | 2.05349 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.03887 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -6.39902 |
| MAPK13 | mitogen-activated protein kinase 13 | -6.01459 |
| HMG20B | high mobility group 20B | -5.02395 |
| ADI1 | acireductone dioxygenase 1 | -4.21449 |
| DSG2 | desmoglein 2 | -4.11722 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.0631 |
| CCNB1 | cyclin B1 | -4.00711 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.92833 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.88915 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.87604 |
| THAP11 | THAP domain containing 11 | -3.84809 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.84506 |
| VAT1 | vesicle amine transport 1 | -3.81853 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -3.7424 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.59717 |
| ISOC1 | isochorismatase domain containing 1 | -3.55836 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.47143 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.43035 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.79195 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.56562 |
| SNX11 | sorting nexin 11 | -2.47211 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.4612 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -2.43731 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.33741 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.15012 |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | -2.07331 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.04288 |
| LDHD | lactate dehydrogenase D | -2.02843 |
| EGF | epidermal growth factor | -2.00369 |
