| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 9-ethyl-9h-carbazol-3-amine hydrochloride 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
86 genes differentially expressed following the CRCGN014_HEPG2_24H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC85B | coiled-coil domain containing 85B | 4.91564 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.69428 |
| SQOR | sulfide quinone oxidoreductase | 4.42302 |
| VAT1 | vesicle amine transport 1 | 4.26885 |
| UBQLN2 | ubiquilin 2 | 3.77176 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.68715 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.28864 |
| CYCS | cytochrome c, somatic | 3.17904 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.10974 |
| INPP1 | inositol polyphosphate-1-phosphatase | 3.09232 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.08168 |
| RAP1GAP | RAP1 GTPase activating protein | 2.89999 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.84863 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.72434 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.70292 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.63284 |
| ZFP36 | ZFP36 ring finger protein | 2.61524 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.57952 |
| TXNRD1 | thioredoxin reductase 1 | 2.57282 |
| MYLK | myosin light chain kinase | 2.55414 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.51403 |
| STAP2 | signal transducing adaptor family member 2 | 2.48801 |
| CTSL | cathepsin L | 2.48581 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.47067 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.41023 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.38894 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.38325 |
| PLSCR1 | phospholipid scramblase 1 | 2.37548 |
| PRR15L | proline rich 15-like | 2.34466 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 2.2864 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | 2.27045 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.22275 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.20366 |
| MYO18A | myosin XVIIIA | 2.20291 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.17054 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.15848 |
| CCDC92 | coiled-coil domain containing 92 | 2.13544 |
| APOC1 | apolipoprotein C-I | 2.10973 |
| MVP | major vault protein | 2.08258 |
| NEMF | nuclear export mediator factor | 2.04489 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 2.02906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.5774 |
| LDHD | lactate dehydrogenase D | -6.15486 |
| ZNF586 | zinc finger protein 586 | -4.55404 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.27592 |
| ANKRD10 | ankyrin repeat domain 10 | -4.03435 |
| TMCO1 | transmembrane and coiled-coil domains 1 | -3.87196 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.69171 |
| CCNB2 | cyclin B2 | -3.51636 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.49226 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -3.41407 |
| CDK1 | cyclin-dependent kinase 1 | -3.32995 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.08341 |
| TLR4 | toll-like receptor 4 | -3.07964 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.01821 |
| PLK1 | polo-like kinase 1 | -3.01528 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.97664 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.86939 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.85573 |
| MELK | maternal embryonic leucine zipper kinase | -2.72567 |
| PGAM4 | phosphoglycerate mutase family member 4 | -2.55105 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.5212 |
| HAT1 | histone acetyltransferase 1 | -2.51556 |
| ZNF274 | zinc finger protein 274 | -2.50818 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.48984 |
| NGRN | neugrin, neurite outgrowth associated | -2.476 |
| SLC35B1 | solute carrier family 35, member B1 | -2.421 |
| GNAS | GNAS complex locus | -2.39709 |
| ICAM3 | intercellular adhesion molecule 3 | -2.35789 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.35219 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.34043 |
| RNASE7 | ribonuclease, RNase A family, 7 | -2.32203 |
| AURKB | aurora kinase B | -2.31182 |
| FHL2 | four and a half LIM domains 2 | -2.27049 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.26961 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.25559 |
| VBP1 | von Hippel-Lindau binding protein 1 | -2.23791 |
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | -2.19398 |
| ASTE1 | asteroid homolog 1 (Drosophila) | -2.18131 |
| HYOU1 | hypoxia up-regulated 1 | -2.13611 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -2.10721 |
| PRKD3 | protein kinase D3 | -2.10248 |
| NUP85 | nucleoporin 85kDa | -2.09735 |
| SNX11 | sorting nexin 11 | -2.08967 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.08695 |
| MTNAP1 | mitochondrial nucleoid associated protein 1 | -2.04611 |
