CRCGN014_HEPG2_24H:K03 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
6.88006
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.43919
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.86425
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.9236
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
3.43951
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.1576
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.98088
|
|
EPHB2
|
EPH receptor B2
|
2.93614
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.42036
|
|
UBQLN2
|
ubiquilin 2
|
2.3868
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.32151
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.28063
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.28012
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.06225
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.26458
|
|
ZNF586
|
zinc finger protein 586
|
-4.01072
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.7826
|
|
VAT1
|
vesicle amine transport 1
|
-3.7376
|
|
THAP11
|
THAP domain containing 11
|
-3.71252
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.52308
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.48926
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.45117
|
|
DNM1L
|
dynamin 1-like
|
-3.34857
|
|
PEG10
|
paternally expressed 10
|
-3.30576
|
|
CDC20
|
cell division cycle 20
|
-3.27054
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.0482
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.99684
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.78537
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.57325
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.42156
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.2647
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.17705
|
|
SCGN
|
secretagogin, EF-hand calcium binding protein
|
-2.156
|
|
TLR4
|
toll-like receptor 4
|
-2.145
|
|
SLC17A5
|
solute carrier family 17 (acidic sugar transporter), member 5
|
-2.04739
|
