CRCGN014_HEPG2_24H:K04 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.21006
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.19648
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.89716
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.87884
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.75986
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.26947
|
|
GATA3
|
GATA binding protein 3
|
2.99385
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.94812
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.7654
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.75442
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.67198
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.57885
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.57129
|
|
THAP12
|
THAP domain containing 12
|
2.48259
|
|
CEP57
|
centrosomal protein 57kDa
|
2.31336
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.3031
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.20298
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.20185
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.11852
|
|
UBL5
|
ubiquitin-like 5
|
2.0463
|
|
MAP7
|
microtubule-associated protein 7
|
2.02472
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-7.19319
|
|
LDHD
|
lactate dehydrogenase D
|
-6.8917
|
|
CCNB2
|
cyclin B2
|
-4.71766
|
|
TLR4
|
toll-like receptor 4
|
-4.42726
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.38915
|
|
VAT1
|
vesicle amine transport 1
|
-4.08549
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.97503
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.51908
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.14453
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.05126
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.92985
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.91485
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.80307
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.57374
|
|
DNM1L
|
dynamin 1-like
|
-2.57334
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.41257
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.245
|
|
AZU1
|
azurocidin 1
|
-2.24007
|
|
RAI14
|
retinoic acid induced 14
|
-2.07047
|