CRCGN014_HEPG2_24H:K07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 41.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN014_HEPG2_24H:K07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 5.47955
EPHB2 EPH receptor B2 4.20039
MYLK myosin light chain kinase 4.0148
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.36717
MAP7 microtubule-associated protein 7 3.11315
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.95921
SMIM40 small integral membrane protein 40 2.61545
CHN1 chimerin 1 2.49317
TBXA2R thromboxane A2 receptor 2.38464
ABHD6 abhydrolase domain containing 6 2.25065
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.17811
ADAM10 ADAM metallopeptidase domain 10 2.00348
ZNF83 zinc finger protein 83 2.00113

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -5.66018
CCNB2 cyclin B2 -3.96261
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.94666
KDM3A lysine (K)-specific demethylase 3A -3.92441
PEG10 paternally expressed 10 -3.83381
CCDC86 coiled-coil domain containing 86 -3.2688
TLR4 toll-like receptor 4 -2.88877
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.59815
DERA deoxyribose-phosphate aldolase (putative) -2.42762
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.31075
SCAND1 SCAN domain containing 1 -2.20462
FKBP4 FK506 binding protein 4, 59kDa -2.14217