CRCGN014_HEPG2_24H:K09 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:K09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.33895
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.85198
|
|
CBR3
|
carbonyl reductase 3
|
4.80972
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
4.51875
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.49569
|
|
NOTCH1
|
notch 1
|
3.92749
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.46164
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.38196
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.97823
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.87063
|
|
MAP7
|
microtubule-associated protein 7
|
2.76706
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.58908
|
|
EPHA3
|
EPH receptor A3
|
2.48166
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.45527
|
|
CYCS
|
cytochrome c, somatic
|
2.33751
|
|
CSK
|
c-src tyrosine kinase
|
2.30296
|
|
PPP1R14B
|
protein phosphatase 1, regulatory (inhibitor) subunit 14B
|
2.28465
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.24366
|
|
LCN2
|
lipocalin 2
|
2.16651
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.75647
|
|
DNM1L
|
dynamin 1-like
|
-5.00624
|
|
LDHD
|
lactate dehydrogenase D
|
-4.91258
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.87553
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.50953
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.11927
|
|
C5
|
complement component 5
|
-3.57242
|
|
CCNB2
|
cyclin B2
|
-3.23038
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.20282
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.72187
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.68105
|
|
HSPA4
|
heat shock 70kDa protein 4
|
-2.23776
|
|
BMP4
|
bone morphogenetic protein 4
|
-2.22426
|
|
PGM1
|
phosphoglucomutase 1
|
-2.07552
|
