CRCGN014_HEPG2_24H:K10 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:K10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.76698
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.38541
|
|
CHN1
|
chimerin 1
|
3.08631
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.90118
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.83947
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.83583
|
|
SLC35A3
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
|
2.80271
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.78673
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.77796
|
|
SATB1
|
SATB homeobox 1
|
2.66188
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.63669
|
|
JADE2
|
jade family PHD finger 2
|
2.14113
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.09734
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-9.97423
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.82688
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.45395
|
|
TLR4
|
toll-like receptor 4
|
-3.45006
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.43447
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.29175
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.11142
|
|
CD320
|
CD320 molecule
|
-2.89366
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.7681
|
|
GNAS
|
GNAS complex locus
|
-2.75268
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.72358
|
|
SNX11
|
sorting nexin 11
|
-2.68911
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.66005
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.54607
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.37612
|
|
PRMT3
|
protein arginine methyltransferase 3
|
-2.28314
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1897
|
|
NUP85
|
nucleoporin 85kDa
|
-2.1862
|
|
PWP1
|
PWP1 homolog (S. cerevisiae)
|
-2.14032
|
|
TES
|
testin LIM domain protein
|
-2.04965
|
