CRCGN014_HEPG2_24H:K16 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_24H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
8.00668
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.48045
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.3
|
|
CBR3
|
carbonyl reductase 3
|
4.25917
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.10533
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.01535
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.0049
|
|
LCN2
|
lipocalin 2
|
3.63187
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.58669
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.58546
|
|
MYLK
|
myosin light chain kinase
|
3.29863
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.1043
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.8283
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.65855
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.53703
|
|
CHN1
|
chimerin 1
|
2.49873
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.4064
|
|
ZNF589
|
zinc finger protein 589
|
2.24795
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.22526
|
|
HOXB2
|
homeobox B2
|
2.21211
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.0841
|
|
MEOX1
|
mesenchyme homeobox 1
|
2.01484
|
|
SEM1
|
SEM1 26S proteasome subunit
|
2.00285
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-7.92512
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.86638
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.81413
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.25349
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.20685
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.97
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.76556
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.71814
|
|
DSG2
|
desmoglein 2
|
-3.54802
|
|
RNF167
|
ring finger protein 167
|
-3.2244
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.94961
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.93341
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.6203
|
|
TLR4
|
toll-like receptor 4
|
-2.56695
|
|
CAB39
|
calcium binding protein 39
|
-2.52502
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.51724
|
|
CCNB2
|
cyclin B2
|
-2.37893
|
|
GDAP1L1
|
ganglioside induced differentiation associated protein 1-like 1
|
-2.25397
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.21003
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.12605
|
|
GNAS
|
GNAS complex locus
|
-2.11067
|
|
PNMA3
|
paraneoplastic Ma antigen 3
|
-2.06041
|
|
SSTR3
|
somatostatin receptor 3
|
-2.02417
|
|
RBM34
|
RNA binding motif protein 34
|
-2.01808
|
