| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fenthion 21.56 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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44 genes differentially expressed following the CRCGN014_HEPG2_24H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.56404 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.89422 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.86974 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.79246 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.75298 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.65869 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.49036 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.3886 |
| DIPK1A | divergent protein kinase domain 1A | 3.25892 |
| MEF2C | myocyte enhancer factor 2C | 3.19502 |
| HDGFL3 | HDGF like 3 | 3.17217 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.12225 |
| PLS1 | plastin 1 | 3.117 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.07216 |
| LCN2 | lipocalin 2 | 2.56728 |
| KIF20A | kinesin family member 20A | 2.55167 |
| PFKL | phosphofructokinase, liver | 2.50211 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.46407 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.45649 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.42159 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 2.10932 |
| MOGAT1 | monoacylglycerol O-acyltransferase 1 | 2.09231 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.08202 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 2.05715 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 2.01159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -9.97377 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.5277 |
| TLR4 | toll-like receptor 4 | -5.6599 |
| TRIB3 | tribbles pseudokinase 3 | -4.21678 |
| TSPAN4 | tetraspanin 4 | -3.6951 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.65938 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.48236 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.36695 |
| SNX11 | sorting nexin 11 | -3.30417 |
| ZNF586 | zinc finger protein 586 | -2.99811 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | -2.81922 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.7252 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.69145 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.63819 |
| CCNB1 | cyclin B1 | -2.48292 |
| HYOU1 | hypoxia up-regulated 1 | -2.42754 |
| RNF167 | ring finger protein 167 | -2.28383 |
| YME1L1 | YME1-like 1 ATPase | -2.11364 |
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | -2.02361 |
