CRCGN014_HEPG2_24H:K19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitrosoazocane 21.1 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN014_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 4.99256
ADGRE5 adhesion G protein-coupled receptor E5 4.6437
MYLK myosin light chain kinase 4.25715
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.85485
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.45661
PLSCR3 phospholipid scramblase 3 2.97205
RXYLT1 ribitol xylosyltransferase 1 2.93566
ZNF589 zinc finger protein 589 2.89469
NPDC1 neural proliferation, differentiation and control, 1 2.84927
LPAR2 lysophosphatidic acid receptor 2 2.82825
GPATCH8 G patch domain containing 8 2.69614
AXIN1 axin 1 2.52349
EPHA3 EPH receptor A3 2.37625
NUCB2 nucleobindin 2 2.3154
CCNF cyclin F 2.24511
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.06598
BPHL biphenyl hydrolase-like (serine hydrolase) 2.00904

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -5.67097
DNM1L dynamin 1-like -5.0904
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.8595
KDM3A lysine (K)-specific demethylase 3A -4.77646
ZNF586 zinc finger protein 586 -4.75101
GTPBP8 GTP-binding protein 8 (putative) -4.51512
ZMIZ1 zinc finger, MIZ-type containing 1 -4.43834
GOLT1B golgi transport 1B -4.4328
TLR4 toll-like receptor 4 -4.39699
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.31333
FGFR4 fibroblast growth factor receptor 4 -3.30898
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.00508
ICAM3 intercellular adhesion molecule 3 -2.92572
NRIP1 nuclear receptor interacting protein 1 -2.03831