CRCGN014_HEPG2_24H:K20 Gene Set
Genes
32 genes differentially expressed following the CRCGN014_HEPG2_24H:K20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
4.26231
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.15474
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.94598
|
|
STIMATE
|
STIM activating enhancer
|
3.42984
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.33994
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.24268
|
|
MOK
|
MOK protein kinase
|
3.22492
|
|
RAB21
|
RAB21, member RAS oncogene family
|
3.22281
|
|
SFTPB
|
surfactant protein B
|
3.15303
|
|
CYCS
|
cytochrome c, somatic
|
2.9475
|
|
CHN1
|
chimerin 1
|
2.93587
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.67206
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.66111
|
|
STK10
|
serine/threonine kinase 10
|
2.37413
|
|
LCN2
|
lipocalin 2
|
2.35537
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.32868
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.09036
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.20026
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.12693
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.93835
|
|
CCNB2
|
cyclin B2
|
-4.75855
|
|
THAP11
|
THAP domain containing 11
|
-3.97634
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-3.58026
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.52321
|
|
LDHD
|
lactate dehydrogenase D
|
-2.97094
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.95191
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.93101
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.7983
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.53539
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.28443
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.19565
|
|
TLR4
|
toll-like receptor 4
|
-2.14502
|
