CRCGN014_HEPG2_24H:K24 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.27731
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.29998
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.37212
|
|
CHN1
|
chimerin 1
|
3.83625
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.71392
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.64479
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.48148
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.34937
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.29298
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.99495
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.68594
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.63285
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.62253
|
|
CRTAP
|
cartilage associated protein
|
2.10627
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.09289
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.04758
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.03788
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.24538
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.84654
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.70796
|
|
RNF167
|
ring finger protein 167
|
-3.61308
|
|
TLR4
|
toll-like receptor 4
|
-3.27628
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.19673
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.01509
|
|
LDHD
|
lactate dehydrogenase D
|
-2.68917
|
|
HAT1
|
histone acetyltransferase 1
|
-2.46809
|
|
GNAS
|
GNAS complex locus
|
-2.45388
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.3154
|
|
CD320
|
CD320 molecule
|
-2.26879
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.25473
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.17639
|
|
PEG10
|
paternally expressed 10
|
-2.09395
|
|
WDR5B
|
WD repeat domain 5B
|
-2.00142
|
