CRCGN014_HEPG2_24H:L03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description l-ascorbic acid 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

535 genes differentially expressed following the CRCGN014_HEPG2_24H:L03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 10.0
MYLK myosin light chain kinase 10.0
UBQLN2 ubiquilin 2 10.0
NUP133 nucleoporin 133kDa 8.7074
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 6.4822
GPER1 G protein-coupled estrogen receptor 1 5.80985
JADE2 jade family PHD finger 2 5.5225
HLA-DRA major histocompatibility complex, class II, DR alpha 5.5023
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 4.9486
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.9153
PLSCR3 phospholipid scramblase 3 4.6824
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 4.6606
LOC122526780 uncharacterized LOC122526780 4.4773
CYCS cytochrome c, somatic 4.2922
SMAD3 SMAD family member 3 4.24085
ANO1 anoctamin 1, calcium activated chloride channel 4.1056
NUDCD3 NudC domain containing 3 3.9097
CCNA1 cyclin A1 3.7886
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 3.7115
CSK c-src tyrosine kinase 3.6119
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 3.5192
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 3.4644
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.4178
PODXL podocalyxin-like 3.3123
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.2781
CYBA cytochrome b-245, alpha polypeptide 3.1558
IRS1 insulin receptor substrate 1 3.1001
TACC1 transforming, acidic coiled-coil containing protein 1 3.04675
GPX7 glutathione peroxidase 7 3.0424
DET1 de-etiolated homolog 1 (Arabidopsis) 3.0206
CASP7 caspase 7, apoptosis-related cysteine peptidase 3.012
UQCRC2 ubiquinol-cytochrome c reductase core protein II 2.9985
CDK5 cyclin-dependent kinase 5 2.9942
CXCL2 chemokine (C-X-C motif) ligand 2 2.9866
GDE1 glycerophosphodiester phosphodiesterase 1 2.9861
SPIN2B spindlin family, member 2B 2.9469
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 2.945
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.8795
CEP57 centrosomal protein 57kDa 2.85446
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 2.7616
ZDHHC7 zinc finger, DHHC-type containing 7 2.7454
CAPN9 calpain 9 2.7153
RPIA ribose 5-phosphate isomerase A 2.6709
CHMP6 charged multivesicular body protein 6 2.6254
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.6165
RALGDS ral guanine nucleotide dissociation stimulator 2.5997
CCNG1 cyclin G1 2.5555
GSTK1 glutathione S-transferase kappa 1 2.5402
TRIM8 tripartite motif containing 8 2.5381
EIF4A1 eukaryotic translation initiation factor 4A1 2.5255
GARS1 glycyl-tRNA synthetase 1 2.5031
TFG TRK-fused gene 2.4943
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.4599
SPON2 spondin 2, extracellular matrix protein 2.4506
DOLK dolichol kinase 2.446
MAN2A1 mannosidase, alpha, class 2A, member 1 2.4345
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 2.43015
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.4252
MIDEAS mitotic deacetylase associated SANT domain protein 2.4009
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.3929
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2.3913
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.3912
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.3877
MTDH metadherin 2.3834
ASPHD1 aspartate beta-hydroxylase domain containing 1 2.3764
DAAM1 dishevelled associated activator of morphogenesis 1 2.3745
OXCT1 3-oxoacid CoA transferase 1 2.3633
RAB38 RAB38, member RAS oncogene family 2.3581
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2.3527
ZNF706 zinc finger protein 706 2.3499
TRAPPC6A trafficking protein particle complex 6A 2.3453
FASTK Fas-activated serine/threonine kinase 2.34153
GET1 guided entry of tail-anchored proteins factor 1 2.3396
CHKA choline kinase alpha 2.33795
CASC3 cancer susceptibility candidate 3 2.3248
UBE2O ubiquitin-conjugating enzyme E2O 2.3179
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.3161
SPDL1 spindle apparatus coiled-coil protein 1 2.3138
CCNC cyclin C 2.3098
C2CD2 C2 calcium-dependent domain containing 2 2.2817
DNAAF2 dynein, axonemal, assembly factor 2 2.2803
SAP30L SAP30-like 2.2692
NADSYN1 NAD synthetase 1 2.267
AGO1 argonaute RISC catalytic component 1 2.2668
CCL21 chemokine (C-C motif) ligand 21 2.2649
BACE1 beta-site APP-cleaving enzyme 1 2.2592
ZIC1 Zic family member 1 2.2534
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.2471
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.2435
TESK2 testis-specific kinase 2 2.2428
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.24175
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.2416
PABPC3 poly(A) binding protein, cytoplasmic 3 2.2381
TMEM126B transmembrane protein 126B 2.2377
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 2.2233
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.2224
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 2.2147
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.21465
TRIM44 tripartite motif containing 44 2.21045
UBE2E3 ubiquitin-conjugating enzyme E2E 3 2.2046
IRF1 interferon regulatory factor 1 2.2009
KLC1 kinesin light chain 1 2.19093
PTH1R parathyroid hormone 1 receptor 2.1832
CCT8 chaperonin containing TCP1, subunit 8 (theta) 2.1809
DENND4B DENN/MADD domain containing 4B 2.1754
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.1728
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.1712
CCNE2 cyclin E2 2.16225
PDIA6 protein disulfide isomerase family A, member 6 2.16147
IRAK1 interleukin-1 receptor-associated kinase 1 2.1544
TP53I3 tumor protein p53 inducible protein 3 2.151
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 2.1483
PGR progesterone receptor 2.1458
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.145
EIF2D eukaryotic translation initiation factor 2D 2.1445
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2.1437
GPR88 G protein-coupled receptor 88 2.1437
DNM1 dynamin 1 2.1364
OPRK1 opioid receptor, kappa 1 2.134
TCTA T-cell leukemia translocation altered 2.1292
CDV3 CDV3 homolog (mouse) 2.12433
REPIN1 replication initiator 1 2.123
SNX17 sorting nexin 17 2.1127
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.1096
PDLIM1 PDZ and LIM domain 1 2.1062
PIMREG PICALM interacting mitotic regulator 2.0969
RTL8C retrotransposon Gag like 8C 2.0966
SMC6 structural maintenance of chromosomes 6 2.0939
CHD3 chromodomain helicase DNA binding protein 3 2.08505
PRDX4 peroxiredoxin 4 2.0828
IMMT inner membrane protein, mitochondrial 2.0791
SAP130 Sin3A-associated protein, 130kDa 2.0783
FZD2 frizzled class receptor 2 2.0758
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 2.0707
PTDSS1 phosphatidylserine synthase 1 2.0572
CTSK cathepsin K 2.0562
ANKRD11 ankyrin repeat domain 11 2.0535
MARCKSL1 MARCKS-like 1 2.0508
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.0484
RAP2A RAP2A, member of RAS oncogene family 2.048
KATNIP katanin interacting protein 2.0464
SEC11A SEC11 homolog A (S. cerevisiae) 2.0453
AMPD2 adenosine monophosphate deaminase 2 2.0439
MPDU1 mannose-P-dolichol utilization defect 1 2.0413
PGCKA1 PDCD10 and GCKIII kinases associated 1 2.0384
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 2.0383
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 2.0353
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.0322
CMC2 C-x(9)-C motif containing 2 2.029
QPRT quinolinate phosphoribosyltransferase 2.0196
GTF2A2 general transcription factor IIA, 2, 12kDa 2.0187
XPO7 exportin 7 2.0128
MINDY1 MINDY lysine 48 deubiquitinase 1 2.0125
TERT telomerase reverse transcriptase 2.0069
SLC45A2 solute carrier family 45, member 2 2.0061
FCMR Fc fragment of IgM receptor 2.0004

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -10.0
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -10.0
PCNA proliferating cell nuclear antigen -10.0
CHMP4B charged multivesicular body protein 4B -9.24405
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -6.9159
TLR4 toll-like receptor 4 -6.2751
RFC2 replication factor C (activator 1) 2, 40kDa -4.94415
ZNF146 zinc finger protein 146 -4.3398
KIF16B kinesin family member 16B -4.2775
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -3.9992
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -3.9121
ADGRB2 adhesion G protein-coupled receptor B2 -3.7639
CAB39 calcium binding protein 39 -3.6239
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -3.5064
CDH4 cadherin 4, type 1, R-cadherin (retinal) -3.39385
FN1 fibronectin 1 -3.38603
CAPNS1 calpain, small subunit 1 -3.3585
DCK deoxycytidine kinase -3.3421
ZNF816 zinc finger protein 816 -3.3391
ATG7 autophagy related 7 -3.3083
CLEC5A C-type lectin domain family 5, member A -3.2858
ECI1 enoyl-CoA delta isomerase 1 -3.2841
STEEP1 STING1 ER exit protein 1 -3.2789
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough -3.27375
APOC1 apolipoprotein C-I -3.21135
CCNDBP1 cyclin D-type binding-protein 1 -3.1814
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -3.1486
NUP155 nucleoporin 155kDa -3.1345
ZNF835 zinc finger protein 835 -3.1319
KCTD17 potassium channel tetramerization domain containing 17 -3.1069
S100A9 S100 calcium binding protein A9 -3.09095
OSMR oncostatin M receptor -3.0579
SETD5 SET domain containing 5 -3.0487
NSFL1C NSFL1 (p97) cofactor (p47) -3.04293
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.9899
UNC13B unc-13 homolog B (C. elegans) -2.9874
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 -2.9665
GPC4 glypican 4 -2.94775
UBOX5 U-box domain containing 5 -2.94
GPR18 G protein-coupled receptor 18 -2.9316
HAUS5 HAUS augmin-like complex, subunit 5 -2.92647
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -2.9041
FBLN2 fibulin 2 -2.9028
LIN37 lin-37 DREAM MuvB core complex component -2.8502
TCTN2 tectonic family member 2 -2.8307
GOLPH3L golgi phosphoprotein 3-like -2.8293
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.8269
CORO2A coronin, actin binding protein, 2A -2.8198
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -2.8192
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.8192
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -2.8057
CXCR2 chemokine (C-X-C motif) receptor 2 -2.7831
TBCB tubulin folding cofactor B -2.77437
PEF1 penta-EF-hand domain containing 1 -2.7568
KLF8 Kruppel-like factor 8 -2.7469
GSTCD glutathione S-transferase, C-terminal domain containing -2.733
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.729
HOXC11 homeobox C11 -2.7249
ZFP30 ZFP30 zinc finger protein -2.7227
TSHB thyroid stimulating hormone, beta -2.7223
TMEM147 transmembrane protein 147 -2.7135
TNIK TRAF2 and NCK interacting kinase -2.70323
ALLC allantoicase -2.7029
FBXO22 F-box protein 22 -2.6974
CSTA cystatin A (stefin A) -2.6947
DEFB126 defensin, beta 126 -2.694
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -2.69395
OVOL2 ovo-like zinc finger 2 -2.6727
CDC37L1 cell division cycle 37-like 1 -2.6725
GSAP gamma-secretase activating protein -2.66925
ADGRG3 adhesion G protein-coupled receptor G3 -2.6555
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -2.6481
RYR1 ryanodine receptor 1 (skeletal) -2.6394
MTCL1 microtubule crosslinking factor 1 -2.6387
PLSCR2 phospholipid scramblase 2 -2.6363
IKZF2 IKAROS family zinc finger 2 (Helios) -2.636
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase -2.6222
DDRGK1 DDRGK domain containing 1 -2.6171
CCN6 cellular communication network factor 6 -2.6119
PRDM13 PR domain containing 13 -2.6059
GPRIN2 G protein regulated inducer of neurite outgrowth 2 -2.601
NXT1 nuclear transport factor 2-like export factor 1 -2.5999
ZNF343 zinc finger protein 343 -2.5973
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 -2.5947
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -2.5944
POF1B premature ovarian failure, 1B -2.5889
VPS50 VPS50 subunit of EARP/GARPII complex -2.5753
NME8 NME/NM23 family member 8 -2.5713
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.5712
IL13RA2 interleukin 13 receptor, alpha 2 -2.5684
CCL27 chemokine (C-C motif) ligand 27 -2.5635
ACOX3 acyl-CoA oxidase 3, pristanoyl -2.5605
BHLHE40 basic helix-loop-helix family, member e40 -2.55955
INTS11 integrator complex subunit 11 -2.5489
TM6SF1 transmembrane 6 superfamily member 1 -2.5484
PLA2G3 phospholipase A2, group III -2.548
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.5351
CLEC4E C-type lectin domain family 4, member E -2.5343
MNDA myeloid cell nuclear differentiation antigen -2.5324
GK glycerol kinase -2.53208
TUBB6 tubulin, beta 6 class V -2.5319
ETV7 ets variant 7 -2.531
AIG1 androgen-induced 1 -2.5302
COPZ1 coatomer protein complex, subunit zeta 1 -2.5269
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -2.5214
HELLS helicase, lymphoid-specific -2.5185
OSER1 oxidative stress responsive serine-rich 1 -2.5147
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -2.5036
TFB1M transcription factor B1, mitochondrial -2.5015
KCNK7 potassium channel, two pore domain subfamily K, member 7 -2.4985
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -2.49567
SLC39A2 solute carrier family 39 (zinc transporter), member 2 -2.4956
PRSS53 protease, serine, 53 -2.4932
WDR83OS WD repeat domain 83 opposite strand -2.491
TWIST1 twist family bHLH transcription factor 1 -2.4899
SOX9 SRY (sex determining region Y)-box 9 -2.48795
SERHL2 serine hydrolase-like 2 -2.48503
POU2F3 POU class 2 homeobox 3 -2.47395
LUZP4 leucine zipper protein 4 -2.4659
EDAR ectodysplasin A receptor -2.4626
MCM6 minichromosome maintenance complex component 6 -2.4581
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.4573
TBX4 T-box 4 -2.4461
STEAP4 STEAP family member 4 -2.4458
EFNA3 ephrin-A3 -2.4415
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.438
KIF26B kinesin family member 26B -2.4355
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -2.4352
ATG101 autophagy related 101 -2.4329
INSL4 insulin-like 4 (placenta) -2.4311
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.4251
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -2.4208
BTBD3 BTB (POZ) domain containing 3 -2.4149
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -2.4074
SYTL3 synaptotagmin-like 3 -2.4044
ZNF253 zinc finger protein 253 -2.4024
PGRMC2 progesterone receptor membrane component 2 -2.40145
TMEM8B transmembrane protein 8B -2.399
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 -2.3987
PRDM5 PR domain containing 5 -2.3974
MKS1 Meckel syndrome, type 1 -2.3972
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -2.3913
OTULINL OTU deubiquitinase with linear linkage specificity like -2.38895
RBM42 RNA binding motif protein 42 -2.3844
WDR18 WD repeat domain 18 -2.3796
SCHIP1 schwannomin interacting protein 1 -2.3761
SYNPO2 synaptopodin 2 -2.3698
CRYM crystallin, mu -2.3696
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.3655
DGCR6L DiGeorge syndrome critical region gene 6-like -2.3651
ZNF571 zinc finger protein 571 -2.3647
TCL1B T-cell leukemia/lymphoma 1B -2.3636
KRT33B keratin 33B, type I -2.3622
CYB5A cytochrome b5 type A (microsomal) -2.35963
USF2 upstream transcription factor 2, c-fos interacting -2.35927
PSORS1C1 psoriasis susceptibility 1 candidate 1 -2.3528
CA9 carbonic anhydrase IX -2.3521
PXDC1 PX domain containing 1 -2.3518
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -2.3488
BMX BMX non-receptor tyrosine kinase -2.3477
SNX15 sorting nexin 15 -2.3446
FAM50B family with sequence similarity 50, member B -2.3431
HMGXB4 HMG box domain containing 4 -2.3395
MEFV Mediterranean fever -2.3342
HHEX hematopoietically expressed homeobox -2.3295
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.3267
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.3254
ATP13A3 ATPase type 13A3 -2.3247
CHIA chitinase, acidic -2.3236
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -2.3224
BRIX1 BRX1, biogenesis of ribosomes -2.3152
OR2B6 olfactory receptor, family 2, subfamily B, member 6 -2.313
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -2.3121
GBE1 glucan (1,4-alpha-), branching enzyme 1 -2.312
TMEM265 transmembrane protein 265 -2.30845
PRKG1 protein kinase, cGMP-dependent, type I -2.30455
MAPK9 mitogen-activated protein kinase 9 -2.3036
SFTPD surfactant protein D -2.3008
FAM204A family with sequence similarity 204, member A -2.2999
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.2996
WDR41 WD repeat domain 41 -2.2996
ELANE elastase, neutrophil expressed -2.2988
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.2943
DYNLT1 dynein, light chain, Tctex-type 1 -2.292
FZD1 frizzled class receptor 1 -2.2884
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.2864
GGTLC1 gamma-glutamyltransferase light chain 1 -2.2802
SLC16A4 solute carrier family 16, member 4 -2.2757
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 -2.2744
MAP3K19 mitogen-activated protein kinase kinase kinase 19 -2.2743
SFTPC surfactant protein C -2.27214
ALPK1 alpha-kinase 1 -2.2714
CETN1 centrin, EF-hand protein, 1 -2.2704
ATP9B ATPase, class II, type 9B -2.2699
BUD31 BUD31 homolog (S. cerevisiae) -2.2675
RPGRIP1L RPGRIP1-like -2.2672
PON3 paraoxonase 3 -2.2663
CARD14 caspase recruitment domain family, member 14 -2.2651
TLX1 T-cell leukemia homeobox 1 -2.2648
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.2643
STRA6 stimulated by retinoic acid 6 -2.2642
DUOX1 dual oxidase 1 -2.2639
C4A complement component 4A (Rodgers blood group) -2.26315
PRR14L proline rich 14-like -2.2609
PSORS1C2 psoriasis susceptibility 1 candidate 2 -2.2607
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -2.2564
FAM174C family with sequence similarity 174 member C -2.2491
LTA lymphotoxin alpha -2.2478
DDR1 discoidin domain receptor tyrosine kinase 1 -2.24677
ITPKC inositol-trisphosphate 3-kinase C -2.2463
TGFBR1 transforming growth factor, beta receptor 1 -2.2457
SEC24C SEC24 family member C -2.2454
CPA4 carboxypeptidase A4 -2.2431
TRIM22 tripartite motif containing 22 -2.2375
PRODH proline dehydrogenase (oxidase) 1 -2.2366
SCARB2 scavenger receptor class B, member 2 -2.23597
TMEM267 transmembrane protein 267 -2.2356
LMO7 LIM domain 7 -2.2334
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.23
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 -2.2293
HRH4 histamine receptor H4 -2.22665
SPRING1 SREBF pathway regulator in golgi 1 -2.2263
DSG3 desmoglein 3 -2.2202
LIM2 lens intrinsic membrane protein 2, 19kDa -2.22
CINP cyclin-dependent kinase 2 interacting protein -2.2165
PHEX phosphate regulating endopeptidase homolog, X-linked -2.2162
MED31 mediator complex subunit 31 -2.2157
FBN1 fibrillin 1 -2.21415
FRAS1 Fraser extracellular matrix complex subunit 1 -2.2118
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.2113
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.2083
INSIG2 insulin induced gene 2 -2.2049
ST7L suppression of tumorigenicity 7 like -2.2048
POPDC2 popeye domain containing 2 -2.2038
SCD5 stearoyl-CoA desaturase 5 -2.2012
CD207 CD207 molecule, langerin -2.2006
OAZ3 ornithine decarboxylase antizyme 3 -2.1993
FPR3 formyl peptide receptor 3 -2.1961
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 -2.1919
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.1915
CRELD1 cysteine-rich with EGF-like domains 1 -2.1874
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.1848
RRH retinal pigment epithelium-derived rhodopsin homolog -2.1848
MAGEA4 melanoma antigen family A4 -2.1845
MIMS2 mitochondrial inner membrane scaffold 2 -2.1835
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -2.18335
VASH1 vasohibin 1 -2.183
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -2.1806
PDCD5 programmed cell death 5 -2.1775
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -2.1771
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.17685
PIBF1 progesterone immunomodulatory binding factor 1 -2.1768
UBA2 ubiquitin-like modifier activating enzyme 2 -2.1762
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.1733
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -2.1697
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 -2.1681
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -2.1675
TGM5 transglutaminase 5 -2.1618
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -2.158
TTC33 tetratricopeptide repeat domain 33 -2.1577
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.1553
NCKIPSD NCK interacting protein with SH3 domain -2.1542
SCN9A sodium channel, voltage gated, type IX alpha subunit -2.1539
PAQR4 progestin and adipoQ receptor family member IV -2.1517
MCC mutated in colorectal cancers -2.1503
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.1498
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.1498
CLDN1 claudin 1 -2.1498
RRM1 ribonucleotide reductase M1 -2.1485
MGAM maltase-glucoamylase -2.148
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 -2.1468
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.14465
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -2.1412
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -2.1387
OR1E1 olfactory receptor, family 1, subfamily E, member 1 -2.1384
SIPA1L3 signal-induced proliferation-associated 1 like 3 -2.1378
FOXC2 forkhead box C2 -2.1372
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.1366
NYX nyctalopin -2.1355
MANSC1 MANSC domain containing 1 -2.1343
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.1315
PSG4 pregnancy specific beta-1-glycoprotein 4 -2.13147
PCDHB8 protocadherin beta 8 -2.1296
MAGEC3 melanoma antigen family C3 -2.127
OR7E24 olfactory receptor, family 7, subfamily E, member 24 -2.124
SNX5 sorting nexin 5 -2.1225
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.1173
DAPK2 death-associated protein kinase 2 -2.11565
ANOS1 anosmin 1 -2.1156
PTK6 protein tyrosine kinase 6 -2.1152
STK32B serine/threonine kinase 32B -2.1146
NMBR neuromedin B receptor -2.1135
RUBCNL rubicon like autophagy enhancer -2.11295
INSL3 insulin-like 3 (Leydig cell) -2.1103
MMP7 matrix metallopeptidase 7 -2.1083
KRTAP2-3 keratin associated protein 2-3 -2.1061
TMEM59L transmembrane protein 59-like -2.1036
COQ4 coenzyme Q4 -2.1
WASHC5 WASH complex subunit 5 -2.0956
ANKH ANKH inorganic pyrophosphate transport regulator -2.0938
CIRBP cold inducible RNA binding protein -2.09305
ZNF430 zinc finger protein 430 -2.0917
CLBA1 clathrin binding box of aftiphilin containing 1 -2.0912
COL1A2 collagen, type I, alpha 2 -2.08965
BMP2K BMP2 inducible kinase -2.08925
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -2.0887
TRIM16 tripartite motif containing 16 -2.0885
TXNDC9 thioredoxin domain containing 9 -2.0848
NCK2 NCK adaptor protein 2 -2.0844
RBM48 RNA binding motif protein 48 -2.0811
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -2.0784
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -2.0773
DYNLRB1 dynein, light chain, roadblock-type 1 -2.0748
KIAA0319 KIAA0319 -2.073
ANKRD6 ankyrin repeat domain 6 -2.07215
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -2.0715
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 -2.06745
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -2.0669
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -2.06587
MMP27 matrix metallopeptidase 27 -2.0636
GAL3ST4 galactose-3-O-sulfotransferase 4 -2.0634
RALY RALY heterogeneous nuclear ribonucleoprotein -2.0622
MARCHF1 membrane associated ring-CH-type finger 1 -2.0622
RUVBL2 RuvB-like AAA ATPase 2 -2.061
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A -2.0605
ATF7 activating transcription factor 7 -2.058
ACTL6A actin-like 6A -2.0576
CHIT1 chitinase 1 (chitotriosidase) -2.0569
SYN1 synapsin I -2.0551
PLCD1 phospholipase C, delta 1 -2.0536
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -2.051
FCHO1 FCH domain only 1 -2.0507
ENG endoglin -2.05055
P4HB prolyl 4-hydroxylase, beta polypeptide -2.04885
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.0473
HESX1 HESX homeobox 1 -2.0464
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.0459
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.0457
LRRC31 leucine rich repeat containing 31 -2.0425
CLDN18 claudin 18 -2.034
TLCD3A TLC domain containing 3A -2.0338
GALP galanin-like peptide -2.033
SCN4A sodium channel, voltage gated, type IV alpha subunit -2.0327
IL18R1 interleukin 18 receptor 1 -2.0322
CCDC6 coiled-coil domain containing 6 -2.0309
GPATCH1 G patch domain containing 1 -2.0305
SPOUT1 SPOUT domain containing methyltransferase 1 -2.03
FAM246A family with sequence similarity 246 member A -2.0288
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -2.0282
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -2.0265
DSG1 desmoglein 1 -2.0262
ZFR2 zinc finger RNA binding protein 2 -2.0262
ZNF557 zinc finger protein 557 -2.0249
ETV4 ets variant 4 -2.0235
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.023
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -2.0194
BCL10 B-cell CLL/lymphoma 10 -2.0174
CXCR1 chemokine (C-X-C motif) receptor 1 -2.0164
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.0152
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) -2.0152
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.0151
IMPACT impact RWD domain protein -2.0149
DOCK5 dedicator of cytokinesis 5 -2.0144
LHCGR luteinizing hormone/choriogonadotropin receptor -2.0142
ITGAV integrin, alpha V -2.0141
IL36A interleukin 36, alpha -2.0127
RPAIN RPA interacting protein -2.0116
KRT1 keratin 1, type II -2.0102
BMAL1 basic helix-loop-helix ARNT like 1 -2.00895
CCDC57 coiled-coil domain containing 57 -2.0079
CNKSR1 connector enhancer of kinase suppressor of Ras 1 -2.0075
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -2.0072
TAS2R13 taste receptor, type 2, member 13 -2.0066
TRAPPC13 trafficking protein particle complex 13 -2.0031
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -2.0019
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -2.0009
KPLCE KPRP N-terminal and LCE C-terminal like protein -2.0007
CD19 CD19 molecule -2.0001
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.00005