CRCGN014_HEPG2_24H:L04 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_24H:L04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
7.86216
|
|
E2F2
|
E2F transcription factor 2
|
4.31088
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.9756
|
|
STK10
|
serine/threonine kinase 10
|
3.73715
|
|
NOTCH1
|
notch 1
|
3.68318
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.56184
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.10907
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.99724
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.96257
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.89261
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.7508
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.61222
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.38031
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.35697
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.35004
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.34406
|
|
MOK
|
MOK protein kinase
|
2.34041
|
|
LASP1
|
LIM and SH3 protein 1
|
2.20967
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.19043
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.04335
|
|
B4GALT4
|
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
|
2.04145
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.7366
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.953
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.97773
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.80297
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.75434
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-3.74336
|
|
GNAS
|
GNAS complex locus
|
-3.66196
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.52891
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.50766
|
|
RPS5
|
ribosomal protein S5
|
-3.33422
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.00924
|
|
THAP11
|
THAP domain containing 11
|
-2.91551
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.59087
|
|
TES
|
testin LIM domain protein
|
-2.58228
|
|
EGF
|
epidermal growth factor
|
-2.57522
|
|
RAI14
|
retinoic acid induced 14
|
-2.51928
|
|
NVL
|
nuclear VCP-like
|
-2.43151
|
|
DNM1L
|
dynamin 1-like
|
-2.36088
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.28633
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.16918
|
|
PIGT
|
phosphatidylinositol glycan anchor biosynthesis, class T
|
-2.14796
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.11667
|
