CRCGN014_HEPG2_24H:L07 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
7.10142
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.2197
|
|
UBQLN2
|
ubiquilin 2
|
3.30102
|
|
NOTCH1
|
notch 1
|
3.19937
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.16082
|
|
MAP7
|
microtubule-associated protein 7
|
3.13608
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.13257
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.95527
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.88418
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.83513
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.671
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.63941
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.52927
|
|
CRYZ
|
crystallin, zeta (quinone reductase)
|
2.51763
|
|
VAT1
|
vesicle amine transport 1
|
2.32308
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.27034
|
|
EPN2
|
epsin 2
|
2.19361
|
|
LCN2
|
lipocalin 2
|
2.16266
|
|
EVL
|
Enah/Vasp-like
|
2.14686
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.06942
|
|
PMM2
|
phosphomannomutase 2
|
2.06455
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.15324
|
|
ZNF586
|
zinc finger protein 586
|
-5.88171
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.37707
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.29714
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.08994
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.82976
|
|
PEG10
|
paternally expressed 10
|
-3.61977
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.31438
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.02903
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.91491
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.91312
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.55772
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.37051
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.28753
|
|
ZNF134
|
zinc finger protein 134
|
-2.14004
|
|
EGF
|
epidermal growth factor
|
-2.12995
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.12315
|
|
LYPLA1
|
lysophospholipase I
|
-2.08263
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.00929
|
