| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-chloro-4'-aminodiphenylether 39.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN014_HEPG2_24H:L08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 6.79889 |
| STK10 | serine/threonine kinase 10 | 6.75846 |
| LCN2 | lipocalin 2 | 5.52586 |
| DDIT4 | DNA-damage-inducible transcript 4 | 3.98838 |
| NUCB2 | nucleobindin 2 | 3.79708 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.49831 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 3.29868 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 3.21751 |
| CDC45 | cell division cycle 45 | 3.12824 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.10303 |
| ABHD6 | abhydrolase domain containing 6 | 3.07541 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 3.06114 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.98482 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 2.97821 |
| TRIB3 | tribbles pseudokinase 3 | 2.86334 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.86332 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.70386 |
| ABHD4 | abhydrolase domain containing 4 | 2.49426 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.45653 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 2.34316 |
| MCM3 | minichromosome maintenance complex component 3 | 2.29125 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.15775 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.14293 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.13115 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.11975 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.07777 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.01661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.69126 |
| TLR4 | toll-like receptor 4 | -4.18634 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.01963 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.45643 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.37977 |
| ZNF586 | zinc finger protein 586 | -3.2008 |
| TCERG1 | transcription elongation regulator 1 | -3.1919 |
| ISOC1 | isochorismatase domain containing 1 | -3.03861 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.93274 |
| GNAS | GNAS complex locus | -2.90082 |
| CDK1 | cyclin-dependent kinase 1 | -2.81099 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.68983 |
| GOLT1B | golgi transport 1B | -2.64974 |
| CCNB2 | cyclin B2 | -2.61299 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -2.54715 |
| CDC20 | cell division cycle 20 | -2.54224 |
| TUBB6 | tubulin, beta 6 class V | -2.54011 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -2.44715 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -2.44146 |
| MELK | maternal embryonic leucine zipper kinase | -2.32014 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.22998 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.22588 |
| IER3 | immediate early response 3 | -2.14418 |
| PLK1 | polo-like kinase 1 | -2.06899 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -2.06652 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | -2.04985 |
| AURKB | aurora kinase B | -2.04799 |
