CRCGN014_HEPG2_24H:L09 Gene Set
Genes
29 genes differentially expressed following the CRCGN014_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.60253
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.78878
|
|
EPHB2
|
EPH receptor B2
|
4.22097
|
|
CHN1
|
chimerin 1
|
3.27316
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.96571
|
|
STK10
|
serine/threonine kinase 10
|
2.89209
|
|
GPATCH8
|
G patch domain containing 8
|
2.68311
|
|
MOK
|
MOK protein kinase
|
2.58594
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.52472
|
|
CHEK2
|
checkpoint kinase 2
|
2.36415
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.34612
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.26498
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.26423
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.30684
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.09941
|
|
LDHD
|
lactate dehydrogenase D
|
-4.69324
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.38217
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.17158
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.68998
|
|
ZNF586
|
zinc finger protein 586
|
-2.40115
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.38567
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.38236
|
|
TEX10
|
testis expressed 10
|
-2.36168
|
|
PLK1
|
polo-like kinase 1
|
-2.32001
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.25772
|
|
SPAG4
|
sperm associated antigen 4
|
-2.25198
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.1201
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.03352
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.0101
|