CRCGN014_HEPG2_24H:L14 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.79902
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.53017
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.00836
|
|
EGF
|
epidermal growth factor
|
3.71584
|
|
CYCS
|
cytochrome c, somatic
|
3.67679
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.47162
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.44564
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.4074
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.27896
|
|
NOTCH1
|
notch 1
|
3.24231
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.93944
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.90364
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.78676
|
|
LCN2
|
lipocalin 2
|
2.55842
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.48686
|
|
STK10
|
serine/threonine kinase 10
|
2.4346
|
|
SLC38A6
|
solute carrier family 38, member 6
|
2.40332
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.33715
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.30576
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.24157
|
|
SIRT2
|
sirtuin 2
|
2.1862
|
|
GNB1L
|
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
|
2.17876
|
|
PRR15L
|
proline rich 15-like
|
2.07429
|
|
SIX1
|
SIX homeobox 1
|
2.05015
|
|
LDHC
|
lactate dehydrogenase C
|
2.0407
|
|
CYB5R1
|
cytochrome b5 reductase 1
|
2.01726
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.04824
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-6.99281
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-6.91837
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.24745
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.13819
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.68647
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.58009
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.57707
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.38437
|
|
SNX11
|
sorting nexin 11
|
-3.19498
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.876
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.75652
|
|
HEG1
|
heart development protein with EGF-like domains 1
|
-2.5674
|
|
GJD3
|
gap junction protein, delta 3, 31.9kDa
|
-2.53846
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.53232
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.26341
|
|
POLD3
|
polymerase (DNA-directed), delta 3, accessory subunit
|
-2.09361
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.08598
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.06306
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.05869
|
