| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | urea 42.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN014_HEPG2_24H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 6.41457 |
| NOTCH1 | notch 1 | 5.73992 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.38482 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.55634 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.15245 |
| MAP7 | microtubule-associated protein 7 | 4.00096 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.86579 |
| MYLK | myosin light chain kinase | 3.80455 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.72045 |
| NOSIP | nitric oxide synthase interacting protein | 3.63522 |
| ATP11B | ATPase, class VI, type 11B | 3.42136 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.36056 |
| CHN1 | chimerin 1 | 2.95077 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.93135 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.81177 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.80912 |
| ADRB2 | adrenoceptor beta 2, surface | 2.68653 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.42139 |
| E2F2 | E2F transcription factor 2 | 2.38099 |
| PRR15L | proline rich 15-like | 2.34471 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.33198 |
| RAB21 | RAB21, member RAS oncogene family | 2.27722 |
| JADE2 | jade family PHD finger 2 | 2.27058 |
| PMM2 | phosphomannomutase 2 | 2.24413 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 2.22911 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.19089 |
| BRCA1 | breast cancer 1, early onset | 2.16304 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | 2.16199 |
| CCNF | cyclin F | 2.07096 |
| GATA2 | GATA binding protein 2 | 2.04662 |
| HDAC5 | histone deacetylase 5 | 2.01283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -5.63203 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.60355 |
| TRIB3 | tribbles pseudokinase 3 | -5.41783 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.99125 |
| TLR4 | toll-like receptor 4 | -3.6218 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.61703 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.57079 |
| LDHD | lactate dehydrogenase D | -3.52701 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.33478 |
| CCDC86 | coiled-coil domain containing 86 | -2.93491 |
| FAIM | Fas apoptotic inhibitory molecule | -2.87978 |
| TES | testin LIM domain protein | -2.87271 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.64419 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.63838 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.59189 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.50051 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.47824 |
| FASTKD5 | FAST kinase domains 5 | -2.47255 |
| EGF | epidermal growth factor | -2.37037 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.33514 |
| NUP85 | nucleoporin 85kDa | -2.1522 |
| TCTN1 | tectonic family member 1 | -2.1108 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.05579 |
| ZNF586 | zinc finger protein 586 | -2.02775 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.00713 |
