| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tetrakis(hydroxymethyl)phos-phonium chloride 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN014_HEPG2_24H:L19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF589 | zinc finger protein 589 | 3.99539 |
| ABHD4 | abhydrolase domain containing 4 | 3.55309 |
| TXNRD1 | thioredoxin reductase 1 | 3.53737 |
| NUCB2 | nucleobindin 2 | 3.39858 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.39765 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.33518 |
| UBQLN2 | ubiquilin 2 | 3.29816 |
| CYCS | cytochrome c, somatic | 3.25763 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.18074 |
| SKIC8 | SKI8 subunit of superkiller complex | 3.13133 |
| E2F2 | E2F transcription factor 2 | 2.97288 |
| STK10 | serine/threonine kinase 10 | 2.83198 |
| VGLL4 | vestigial-like family member 4 | 2.82283 |
| NOSIP | nitric oxide synthase interacting protein | 2.74089 |
| GATA3 | GATA binding protein 3 | 2.58181 |
| PLSCR1 | phospholipid scramblase 1 | 2.57634 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.56536 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.50977 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.4888 |
| DIPK1A | divergent protein kinase domain 1A | 2.47333 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.42058 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.39922 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.36191 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.33033 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 2.24479 |
| CDC45 | cell division cycle 45 | 2.23958 |
| TRIB3 | tribbles pseudokinase 3 | 2.22061 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.2042 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.19211 |
| MVP | major vault protein | 2.13638 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.02283 |
| GLRX | glutaredoxin (thioltransferase) | 2.00368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSRC1 | proline/serine-rich coiled-coil 1 | -4.37021 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -4.16461 |
| GNAS | GNAS complex locus | -4.06801 |
| NUP93 | nucleoporin 93kDa | -4.06362 |
| PUF60 | poly-U binding splicing factor 60KDa | -4.03921 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -3.86885 |
| CCNA2 | cyclin A2 | -3.7032 |
| CDC20 | cell division cycle 20 | -3.6535 |
| SNX11 | sorting nexin 11 | -3.47826 |
| PLK1 | polo-like kinase 1 | -3.39982 |
| AURKB | aurora kinase B | -3.35485 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.26357 |
| MELK | maternal embryonic leucine zipper kinase | -3.19407 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -3.12209 |
| LDHD | lactate dehydrogenase D | -3.00836 |
| CCNB2 | cyclin B2 | -2.95867 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.85645 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -2.83881 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -2.76249 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.6 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.46997 |
| CTSL | cathepsin L | -2.41831 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.40085 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.30215 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.26003 |
| TMEM109 | transmembrane protein 109 | -2.24571 |
| CDK1 | cyclin-dependent kinase 1 | -2.08559 |
| CCNB1 | cyclin B1 | -2.07267 |
| HOXB13 | homeobox B13 | -2.03181 |
