CRCGN014_HEPG2_24H:L20 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:L20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABHD4
|
abhydrolase domain containing 4
|
4.37973
|
|
LCN2
|
lipocalin 2
|
3.93593
|
|
EVL
|
Enah/Vasp-like
|
3.87559
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.63076
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.59293
|
|
TXNRD1
|
thioredoxin reductase 1
|
3.51994
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
3.30407
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.11254
|
|
CBR3
|
carbonyl reductase 3
|
3.09605
|
|
CHN1
|
chimerin 1
|
3.03079
|
|
UBQLN2
|
ubiquilin 2
|
3.02646
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
2.83662
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.8039
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.78527
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.75399
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.63006
|
|
CYCS
|
cytochrome c, somatic
|
2.60863
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
2.58732
|
|
PMM2
|
phosphomannomutase 2
|
2.44926
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.38586
|
|
AXIN1
|
axin 1
|
2.38404
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.29253
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.24154
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.19379
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
2.08465
|
|
CBR1
|
carbonyl reductase 1
|
2.0169
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.45605
|
|
ZNF586
|
zinc finger protein 586
|
-4.19716
|
|
CDC20
|
cell division cycle 20
|
-3.38909
|
|
CD320
|
CD320 molecule
|
-3.31699
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.15716
|
|
VAT1
|
vesicle amine transport 1
|
-3.03645
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.92649
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.90577
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.78665
|
|
GOLT1B
|
golgi transport 1B
|
-2.75658
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.72862
|
|
PEG10
|
paternally expressed 10
|
-2.61412
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.44273
|
|
RNF167
|
ring finger protein 167
|
-2.32173
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
-2.31928
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.24492
|
|
EGF
|
epidermal growth factor
|
-2.20604
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.13999
|
